Results 121 to 130 of about 574,813 (298)

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim   +7 more
wiley   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

open access: yesAdvanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei   +10 more
wiley   +1 more source

Cellulosic Functional Bioplastic with Tunable Strength and Toughness Through Heat‐Treatment of Dynamic Covalent Networks

open access: yesAdvanced Science, EarlyView.
A fully bio‐based dynamic covalent network is constructed via Diels‐Alder chemistry between furan‐modified cellulose derivatives and bismaleimide‐functionalized lignin. This system enables tunable strength‐ductility balance through heat‐treatment and exhibits excellent recyclability.
Xiangyu Tang   +9 more
wiley   +1 more source

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