Results 41 to 50 of about 1,150,643 (361)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Effect of Chitosan Coating and Storage Temperature on Shelf-Life and Fruit Quality of Ziziphus Mauritiana

International Journal of Fruit Science, 2021
Due to short shelf-life of ber fruits, developing postharvest protocols incorporating nonchemical compounds with the aim of extending its shelf life and maintaining quality is one of the major issues regarding ber fruit industry.
A. Hesami, Setareh Kavoosi, Rahim Khademi, S. Sarikhani   +3 more
semanticscholar   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

Alteration of TAC1 expression in Prunus species leads to pleiotropic shoot phenotypes

Horticulture Research, 2018
Fruit trees: Slimmer trees for denser planting Peach and plum trees grow tall and slim when the TAC1 gene is mutated, permitting higher-density planting in orchards. Branches of peach trees with the “pillar” trait grow more “up” than “out”, reducing each
Courtney A. Hollender, Jessica M. Waite, Amy Tabb, Doug Raines, Srinivasan Chinnithambi, Chris Dardick   +5 more
doaj   +1 more source

RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

Genome Biology, 2019
Methylation of nucleotides, notably in the forms of 5-methylcytosine (5mC) in DNA and N6-methyladenosine (m6A) in mRNA, carries important information for gene regulation. 5mC has been elucidated to participate in the regulation of fruit ripening, whereas
Leilei Zhou, S. Tian, G. Qin
semanticscholar   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Full-length transcriptome profiling reveals insight into the cold response of two kiwifruit genotypes (A. arguta) with contrasting freezing tolerances

BMC Plant Biology, 2021
Background Kiwifruit (Actinidia Lindl.) is considered an important fruit species worldwide. Due to its temperate origin, this species is highly vulnerable to freezing injury while under low-temperature stress. To obtain further knowledge of the mechanism
Shihang Sun, Miaomiao Lin, Xiujuan Qi, Jinyong Chen, Hong Gu, Yunpeng Zhong, Leiming Sun, Abid Muhammad, Danfeng Bai, Chungen Hu, Jinbao Fang   +10 more
doaj   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

Advanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

Results of some apple hybrids populations to the attack of scab and powdery mildew under natural conditions

Romanian Journal of Horticulture
Apple scab, caused by the fungus Venturia inaequalis, and powdery mildew, caused by the fungus Podosphaera leucotricha, are two of the most significant diseases affecting apple production worldwide.
G. M. Guzu, S.D. Roșu Mareș, C. Moldovan, I. Zagrai, L. A. Zagrai, M. I. Cordea   +5 more
doaj   +1 more source

Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: systematic review and dose-response meta-analysis of prospective cohort studies

British medical journal, 2014
Objective To examine and quantify the potential dose-response relation between fruit and vegetable consumption and risk of all cause, cardiovascular, and cancer mortality.
Xia Wang, Yingying Ouyang, Jun Liu, Minmin Zhu, Gang Zhao, W. Bao, F. Hu   +6 more
semanticscholar   +1 more source