Diagnostic accuracy of Loopamp Trypanosoma brucei detection kit for diagnosis of human African trypanosomiasis in clinical samples [PDF]
Background: Molecular methods have great potential for sensitive parasite detection in the diagnosis of human African trypanosomiasis (HAT), but the requirements in terms of laboratory infrastructure limit their use to reference centres.
Dieudonné Mumba Ngoyi +9 more
core +21 more sources
How to Start a Food Business: Writing a Business Plan
Before starting a new food business, you should set a goal and have detailed plans to accomplish that goal. But writing a good business plan is often a challenge and it requires a great amount of effort.
Soohyoun Ahn +2 more
doaj +5 more sources
The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question [PDF]
Human African trypanosomiasis (HAT), also known as sleeping sickness, puts millions of people at risk in sub-Saharan Africa and is a neglected parasitic disease that is almost always fatal if untreated or inadequately treated. HAT manifests itself in two
Gettinby, George +2 more
core +1 more source
Integrated cost-benefit analysis of tsetse control and herd productivity to inform control programs for animal African trypanosomiasis [PDF]
Animal African trypanosomiasis (AAT) and its tsetse vector are responsible for annual losses estimated in billions of US dollars ($). Recent years have seen the implementation of a series of multinational interventions.
Chilongo, K +7 more
core +1 more source
In vitro activity of salinomycin and monensin derivatives against Trypanosoma brucei [PDF]
Background: African trypanosomes are the causative agents of sleeping sickness in humans and nagana disease in livestock animals. As the few drugs available for treatment of the diseases have limited efficacy and produce adverse reactions, new and better
A Huczyński +24 more
core +1 more source
Nanobodies as tools to understand, diagnose, and treat African trypanosomiasis [PDF]
African trypanosomes are strictly extracellular protozoan parasites that cause diseases in humans and livestock and significantly affect the economic development of sub-Saharan Africa.
Caljon, Guy +5 more
core +1 more source
African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar +160 more
core +1 more source
Whole-genome sequencing of trypanosoma brucei reveals introgression between subspecies that is associated with virulence [PDF]
Human African trypanosomiasis is caused by two subspecies of Trypanosoma brucei. Trypanosoma brucei rhodesiense is found in East Africa and frequently causes acute disease, while Trypanosoma brucei gambiense is found in West Africa and is associated with
Apted +35 more
core +5 more sources
: The impact of war on the evolution of sleeping sickness in west-central Cote d'Ivoire [PDF]
International audienceTo evaluate the situation of sleeping sickness in west-central Cote d'Ivoire from 2000 to 2003, in view of the war which broke out in September 2002. Active surveys by medical teams and passive case detection. Between 2000 and 2003,
Courtin, Fabrice +7 more
core +3 more sources
Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine [PDF]
Sleeping sickness is an infectious disease that is caused by the protozoan parasite Trypanosoma brucei. The second stage of the disease is characterised by the parasites entering the brain.
Rushworth, Stuart A. +1 more
core +1 more source

