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From Metabolic Syndrome to Neurological Diseases: Role of Autophagy

open access: yesFrontiers in Cell and Developmental Biology, 2021
Metabolic syndrome is not a single pathology, but a constellation of cardiovascular disease risk factors including: central and abdominal obesity, systemic hypertension, insulin resistance (or type 2 diabetes mellitus), and atherogenic dyslipidemia.
Jessica Maiuolo   +15 more
doaj   +1 more source

The Contribution of Gut Microbiota–Brain Axis in the Development of Brain Disorders

open access: yesFrontiers in Neuroscience, 2021
Different bacterial families colonize most mucosal tissues in the human organism such as the skin, mouth, vagina, respiratory, and gastrointestinal districts.
Jessica Maiuolo   +16 more
doaj   +1 more source

The Phytochemical Synergistic Properties of Combination of Bergamot Polyphenolic Fraction and Cynara cardunculus Extract in Non-Alcoholic Fatty Liver Disease

open access: yesAgriculture, 2023
Non-alcoholic fatty liver disease (NAFLD) is considered one of the leading causes of liver-related morbidity and mortality. NAFLD is a cluster of liver disorders that includes the accumulation of fat in the liver, insulin resistance, diffuse steatosis ...
Jessica Maiuolo   +19 more
doaj   +1 more source

Potential Properties of Natural Nutraceuticals and Antioxidants in Age-Related Eye Disorders

open access: yesLife, 2022
Eye health is crucial, and the onset of diseases can reduce vision and affect the quality of life of patients. The main causes of progressive and irreversible vision loss include various pathologies, such as cataracts, ocular atrophy, corneal opacity ...
Jessica Maiuolo   +18 more
doaj   +1 more source

Oxidative Stress Triggers Defective Autophagy in Endothelial Cells: Role in Atherothrombosis Development

open access: yesAntioxidants, 2021
Atherothrombosis, a multifactorial and multistep artery disorder, represents one of the main causes of morbidity and mortality worldwide. The development and progression of atherothrombosis is closely associated with age, gender and a complex ...
Cristina Carresi   +15 more
doaj   +1 more source

Ferula communis L. (Apiaceae) Root Acetone-Water Extract: Phytochemical Analysis, Cytotoxicity and In Vitro Evaluation of Estrogenic Properties

open access: yesPlants, 2022
Ferula communis L. (F. communis) belongs to the Apiaceae family and is a herbaceous plant with various pharmaceutical properties, due to the different contents of bioactive compounds extracted mainly from its roots, as well as its leaves and rhizome.
Jessica Maiuolo   +12 more
doaj   +1 more source

Protective Role of an Extract Waste Product from Citrus bergamia in an In Vitro Model of Neurodegeneration

open access: yesPlants, 2023
A balanced diet, rich in fruits and vegetables and ensuring the intake of natural products, has been shown to reduce or prevent the occurrence of many chronic diseases.
Jessica Maiuolo   +10 more
doaj   +1 more source

Ferula L. Plant Extracts and Dose-Dependent Activity of Natural Sesquiterpene Ferutinin: From Antioxidant Potential to Cytotoxic Effects

open access: yesMolecules, 2020
The employment studies of natural extracts in the prevention and treatment of several diseases highlighted the role of different species of genus Ferula L., belonging to the Apiaceae family, dicotyledonous plants present in many temperate zones of our ...
Roberta Macrì   +13 more
doaj   +1 more source

MAFLD progression contributes to altered thalamus metabolism and brain structure

open access: yesScientific Reports, 2022
Metabolic associated fatty liver disease (MAFLD), commonly known as non-alcoholic fatty liver disease, represents a continuum of events characterized by excessive hepatic fat accumulation which can progress to nonalcoholic steatohepatitis (NASH ...
Saverio Nucera   +19 more
doaj   +1 more source

Endothelial Dysfunction and Extra-Articular Neurological Manifestations in Rheumatoid Arthritis

open access: yesBiomolecules, 2021
Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory autoimmune disease that affects about 1% of the global population, with a female–male ratio of 3:1.
Jessica Maiuolo   +9 more
doaj   +1 more source

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