Results 61 to 70 of about 65,143 (262)

SIRT1: A likely key for future therapeutic strategies for pain management

Pharmacological Research
Sirtuin 1 (SIRT1), a NAD+ -dependent histone deacetylase, plays a crucial role in mitigating oxidative stress, regulating inflammation, and maintaining mitochondrial function. Reduced SIRT1 activity has been linked to elevated pro-inflammatory cytokines,
Sara Ilari, Saverio Nucera, Lucia Carmela Passacatini, Rosamaria Caminiti, Valeria Mazza, Roberta Macrì, Maria Serra, Federica Scarano, Valentina Malafoglia, Ernesto Palma, Francesca Oppedisano, Jessica Maiuolo, Carlo Tomino, Vincenzo Mollace, Carolina Muscoli   +14 more
doaj   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source

The potential effect of natural antioxidants on endothelial dysfunction associated with arterial hypertension

Frontiers in Cardiovascular Medicine
Arterial hypertension represents a leading cause of cardiovascular morbidity and mortality worldwide, and the identification of effective solutions for treating the early stages of elevated blood pressure (BP) is still a relevant issue for cardiovascular
Rosamaria Caminiti, Cristina Carresi, Rocco Mollace, Rocco Mollace, Roberta Macrì, Federica Scarano, Francesca Oppedisano, Jessica Maiuolo, Maria Serra, Stefano Ruga, Saverio Nucera, Annamaria Tavernese, Micaela Gliozzi, Vincenzo Musolino, Ernesto Palma, Carolina Muscoli, Carolina Muscoli, Speranza Rubattu, Speranza Rubattu, Maurizio Volterrani, Massimo Federici, Massimo Volpe, Vincenzo Mollace, Vincenzo Mollace   +23 more
doaj   +1 more source

Luteal phase stimulation versus follicular phase stimulation in poor ovarian responders: A systematic review and a meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Poor ovarian response (POR) complicates a substantial proportion of in vitro fertilization (IVF) cycles, frequently causing cycle cancellation and suboptimal reproductive outcomes. Conventional follicular‐phase ovarian stimulation (FPOS) protocols often yield limited results, prompting the evaluation of alternative strategies such ...
Vittorio Agrifoglio, Antonio D'Amato, Mariano Catello Di Donna, Marika Marino, Antonio Simone Laganà, Renato Venezia, Davide Vinci, Gaetano Riemma, Andrea Etrusco   +8 more
wiley   +1 more source

Targeting leptin/CCL3-CCL4 axes in NAFLD/MAFLD: A novel role for BPF in counteracting thalamic inflammation and white matter degeneration

Pharmacological Research
Non-alcoholic fatty liver disease (NAFLD), redefined as Metabolic Associated Fatty Liver Disease (MAFLD), is characterized by an extensive multi-organ involvement.
Antonio Cardamone, Anna Rita Coppoletta, Roberta Macrì, Saverio Nucera, Stefano Ruga, Federica Scarano, Rocco Mollace, Annachiara Mollace, Samantha Maurotti, Edoardo Micotti, Cristina Carresi, Vincenzo Musolino, Micaela Gliozzi, Vincenzo Mollace   +13 more
doaj   +1 more source

Enhancement of some sex hormones concentrations by consumption of leaves extract of Viscum album (mistletoe) in rats

Asian Journal of Medical Sciences, 2014
Objective: This present study was conducted with the aim to investigate the effect of consumption of leaves extract of mistletoe on the concentration of some serum sex hormones (follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone ...
Ofem Effiong Ofem
doaj   +1 more source

Subclinical cardiac alterations and cardiometabolic profile in adolescents with newly diagnosed polycystic ovary syndrome: A cross‐sectional comparative echocardiographic study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective While cardiometabolic comorbidities have been well established in adults with polycystic ovary syndrome (PCOS), it remains unclear whether the early signs of cardiovascular morbidity emerge during adolescence. This study aimed to investigate whether metabolic and cardiovascular alterations begin in adolescents with PCOS.
Demet Aygün Ari, Melis Pehlivantürk Kizilkan, Musa Öztürk, İlker Ertuğrul, Hayrettin Hakan Aykan, Tevfik Karagöz, Nuray Kanbur, Orhan Derman, Sinem Akgül   +8 more
wiley   +1 more source

Young bodies, aging ovaries: A systematic review and meta‐synthesis of women's perspectives on spontaneous premature ovarian insufficiency

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives Spontaneous premature ovarian insufficiency (POI) is a condition characterized by the cessation of ovarian function before age 40, unrelated to medical interventions. It affects approximately 3.5% of women worldwide and can result in significant emotional, physical, and social consequences.
Maria Patricia Roman, Shaurya Aggarwal, Stergios K. Doumouchtsis   +2 more
wiley   +1 more source

Alterations in Pituitary Follicle-Stimulating Hormone (FSH) and Hypothalamic FSH-Releasing Factor (FSH-RF) during Puberty

Experimental Biology and Medicine, 1969
SummaryA decline in pituitary FSH concentration and content was associated with prepubertal development of female rats. A further decline in pituitary FSH concentration occurred at the time of vaginal opening, but pituitary FSH content fell only slightly at this time because of a concurrent increase in anterior pituitary weight.
S, Watanabe, S M, McCann
openaire   +2 more sources

Surgically confirmed severe endometriosis is associated with lower risk of steatotic liver disease: Evidence of estrogen‐linked hepatic–reproductive crosstalk

International Journal of Gynecology &Obstetrics, EarlyView.
Severe surgically confirmed endometriosis was associated with a lower prevalence of steatotic liver disease than non‐severe disease. Higher estradiol levels may partly explain this inverse hepatic–reproductive association, supporting integrated gynecologic and hepatologic risk assessment.
Jung Hyun Park, Keungmo Yang, Hyun Yang, Si Hyun Bae, Mee‐Ran Kim, Jaejun Lee   +5 more
wiley   +1 more source