Results 81 to 90 of about 1,388,477 (251)

Genetic Etiologies of Dystonia with Anarthria/Aphonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dystonia with anarthria and/or aphonia (DAnAp) represents a distinctive phenotype manifesting across lifespan. Frequently associated with genetic disorders, early recognition is critical for diagnosis and management. Objectives To provide practical recommendations for the clinical evaluation of patients with DAnAp, enhancing ...
Anika Ménétrey, Eriberto Rayco, Maziar Emamikhah Abarghouei, Susan H. Fox, Anthony E. Lang, George M. Ibrahim, Carolina Gorodetsky, Christos Ganos   +7 more
wiley   +1 more source

CARTPT and FSH Signaling in Ovarian Follicle Development as an Emerging Link to Oocyte Quality and Female Infertility

Current Issues in Molecular Biology
Not all ovarian follicles respond to follicle-stimulating hormone (FSH) in the same way. This difference is usually attributed to FSH receptor expression and local ovarian factors, but the role of CARTPT has received far less attention.
Charalampos Voros, Fotios Chatzinikolaou, Georgios Papadimas, Diamantis Athanasiou, Antonia Athanasiou, Aikaterini Athanasiou, Nikolaos Thomakos, Panagiotis Antsaklis, Dimitrios Loutradis, Georgios Daskalakis   +9 more
doaj   +1 more source

From Long‐Term to Trial‐Ready: 1.5‐Year Follow‐Up in an Established FSHD Cohort Highlights Limitations of Current Outcome Measures

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Identifying endpoints that are sensitive to change is crucial for clinical trial design in facioscapulohumeral muscular dystrophy (FSHD). This study adds follow‐up data to a previously published 5‐year natural history study in the same cohort, aiming to correlate short‐term disease progression to longer term follow‐up ...
Sjan Teeselink, Sanne C. C. Vincenten, Amir Chaman Baz, Nicol C. Voermans, Nens van Alfen, Baziel G. M. van Engelen, Karlien Mul   +6 more
wiley   +1 more source

CD28 co-stimulatory domain enhances efficacy of CER T cell therapy compared to 4-1BB in an ovarian cancer mouse model

Scientific Reports
Ovarian cancer remains a significant cause of cancer-related mortality, with epithelial ovarian cancer (EOC) being the most common subtype. Despite advances in treatment, the 5-year survival rate for late-stage EOC remains low due to factors such as ...
Nolan J. Beatty, Min Ma, Payal Goala, Shannon McSain, Sae Bom Lee, Justin C. Boucher, Meredith L. Stone, Yun Pyo Kang, Eduardo Cortes-Gomez, Jianmin Wang, Jun Qu, Marco L. Davila   +11 more
doaj   +1 more source

From Isolated to Complex: Diagnostic Yield of Chromosomal Microarray and Exome Sequencing in Fetal Growth Restriction

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To characterize the overall diagnostic yield of sequential chromosomal microarray (CMA) and exome sequencing (ES) across the phenotypic spectrum of fetal growth restriction (FGR). Methods A retrospective cohort of 320 consecutive FGR pregnancies presenting at ≥ 20 weeks to a tertiary fetal medicine unit (2020–2025).
Hadas Miremberg, May Shabat, Maya Stok, Vered Offer Glasner, Adi Botvinik, Mordechai Shohat, Michal Levy, Yuval Yaron, Roee Birnbaum, Sharon Perlman, Gustavo Malinger, Karina Krajden Haratz   +11 more
wiley   +1 more source

Mechanism of Action of Fsh in the Induction of Lh Receptor.

, 1981
This thesis examines the mechanisms by which follicle stimulating hormone (FSH) induces luteinizing hormone (LH)/human chorionic gonadotropin (hCG) receptor. A primary granulosa cell culture system was developed to allow the examination of the effects of
Sanders, Michel Mane
core   +2 more sources

Research progress on FSH-FSHR signaling in the pathogenesis of non-reproductive diseases

Frontiers in Cell and Developmental Biology
Follicle-stimulating hormone (FSH), a glycoprotein hormone synthesized and secreted by the anterior pituitary gland, plays a critical role in reproductive development and regulation by binding to FSH receptor (FSHR).
Chenhe Li, Chenhe Li, Yan Ling, Haibin Kuang   +3 more
doaj   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

Identification of the FSH-RH as the other gonadotropin-releasing hormone

Nature Communications
In vertebrates, folliculogenesis and ovulation are regulated by two distinct pituitary gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Shun Kenny Uehara, Yuji Nishiike, Kazuki Maeda, Tomomi Karigo, Shigehiro Kuraku, Kataaki Okubo, Shinji Kanda   +6 more
doaj   +1 more source

Follicle-stimulating hormone glycoform interactions with the FSH receptor

, 2015
Thesis (M.S.)--Wichita State University, Fairmount College of Liberal Arts and Sciences, Dept. of Biological SciencesFollicle-stimulating hormone (FSH) is a gonadotropic hormone produced by the ante-rior pituitary, which plays a major role in follicular ...
Elsaid, Ramy E.
core