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Iron overload modulates follicular microenvironment via ROS/HIF-1α/FSHR signaling
Free Radical Biology and Medicine, 2023Iron is essential for the health of reproductive system, and women with iron overload suffer from ovarian dysfunction and lack effective treatment in fertility preservation. However, the underlying mechanism of the detrimental effects of iron overload on ovarian function remains ambiguous. Here, we confirmed the excess iron in the circumjacent follicle
Yaoqiu, Wu +11 more
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2014
Innate immunity is critical for all organisms against microbial pathogens. It is the first line of defense that organisms possess and is used in the activation of adaptive immune response in mammalian vertebrates. Many pathways have been identified as being key to innate immunity regulation. Recently a G protein coupled receptor, FSHR-1, was identified
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Innate immunity is critical for all organisms against microbial pathogens. It is the first line of defense that organisms possess and is used in the activation of adaptive immune response in mammalian vertebrates. Many pathways have been identified as being key to innate immunity regulation. Recently a G protein coupled receptor, FSHR-1, was identified
openaire +1 more source
FSH glycosylation variants differentially modulate FSHR trafficking
Endocrine Abstracts, 2022Uche Agwuegbo +4 more
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