Results 21 to 30 of about 439 (154)

Environmental Sources, Chemistry, Fate, and Transport of Per‐ and Polyfluoroalkyl Substances: State of the Science, Key Knowledge Gaps, and Recommendations Presented at the August 2019 SETAC Focus Topic Meeting

Environmental Toxicology and Chemistry, Volume 40, Issue 12, Page 3234-3260, December 2021., 2021
Abstract A Society of Environmental Toxicology and Chemistry (SETAC) Focused Topic Meeting (FTM) on the environmental management of per‐ and polyfluoroalkyl substances (PFAS) convened during August 2019 in Durham, North Carolina (USA). Experts from around the globe were brought together to critically evaluate new and emerging information on PFAS ...
Jennifer L. Guelfo, Stephen Korzeniowski, Marc A. Mills, Janet Anderson, Richard H. Anderson, Jennifer A. Arblaster, Jason M. Conder, Ian T. Cousins, Kavitha Dasu, Barbara J. Henry, Linda S. Lee, Jinxia Liu, Erica R. McKenzie, Janice Willey   +13 more
wiley   +1 more source

Refining the amyloid β peptide and oligomer fingerprint ambiguities in Alzheimer’s disease: Mass spectrometric molecular characterization in brain, cerebrospinal fluid, blood, and plasma

Journal of Neurochemistry, Volume 159, Issue 2, Page 234-257, October 2021., 2021
Amyloid‐β is the principal target of investigation in Alzheimer's disease. In this review, we are revisiting the history of Amyloid‐β's discovery and its initial characterization, including the crucial role mass spectrometry has played in this process. We then move on to discuss how mass spectrometry can aid in the characterization of toxic oligomeric ...
Wojciech Michno, Kaj Blennow, Henrik Zetterberg, Gunnar Brinkmalm   +3 more
wiley   +1 more source

The Fluorescent Amyloid Ligand X34 Binding to Transthyretin (TTR) Tetramer and Fibrils: FRET and Binding Constants of a Sequential Two‐step Process

ChemPhotoChem, Volume 9, Issue 2, February 2025.
A secret of life is molecular recognition; the ability of one molecule to recognize another through weak bonding interactions. Here we investigate a fluorescent amyloid ligand X34 and its binding propensity to two apparently asymmetric binding sites of the amyloidogenic plasma protein transthyretin (TTR), both in its native tetrameric form and as an ...
Marikken Sundnes, Priyanka Swaminathan, Mikael Lindgren, Ganesh Mohite, Ebba Hellstrand, Sofie Nyström, Per Hammarström   +6 more
wiley   +1 more source

Beyond simplistic narratives: Dynamic farmers, precarity and the politics of agribusiness expansion

Journal of Agrarian Change, Volume 24, Issue 4, October 2024.
Abstract Agribusiness expansion is usually framed around two competing narratives. On the one hand, advocates present it as a promising vehicle to modernise agriculture and integrate small farmers into global value chains. On the other hand, critics denounce it as a top‐down corporate assault to monopolise agriculture and dispossess peasants of land ...
Enrique Castañón Ballivián
wiley   +1 more source

Amyloid beta 1‐40 and 1‐42 fibril ratios and maturation level cause conformational differences with minimal impact on autophagy and cytotoxicity

Journal of Neurochemistry, Volume 168, Issue 9, Page 3308-3322, September 2024.
The amyloid β (Aβ) peptide varies in length between 37 and 49 amino acids, with Aβ1‐42 being the most disease‐related and forms plaques in Alzheimer's disease. Aβ1‐40 also forms plaques and intertwines with Aβ1‐42, but their combined effect is still not clearly understood. Here, we fibrillized different Aβ1‐40:42 ratios and characterized both early and
Lovisa Johansson, Alexander Sandberg, Sofie Nyström, Per Hammarström, Martin Hallbeck   +4 more
wiley   +1 more source

Amino‐Acid Side‐Chain Nanoarchitectonics for Tuning the Chiroptical Properties and Supramolecular Structure of Pentameric Oligothiophenes

ChemPhotoChem, Volume 8, Issue 7, July 2024.
Self‐assembled Proteophenes. Oligothiophenes with distinct amino acid side‐chain functionalities along the conjugated backbone displayed distinct chiroptical and structural properties in acidic or alkaline solutions. The distinct photophysical characteristics, as well as the supramolecular structures of the assemblies were highly influenced by the ...
Linnea Björk, Robert Selegård, Marcus Bäck, Per Hammarström, Mikael Lindgren, K. Peter R. Nilsson   +5 more
wiley   +1 more source

Limitations of the knee society score in kinematically aligned total knee arthroplasty

Journal of Experimental Orthopaedics, Volume 11, Issue 3, July 2024.
Abstract Purpose The Knee Society Scoring System (KSS) is a frequently used outcome score which quantifies functional patients' outcomes before and after total knee arthroplasty (TKA). Several problems arise when trying to implement KSS for obtaining postoperative outcomes after more personalised aligned TKAs. Scoring for valgus femorotibial angle (FTA)
Alexandra Leica, Manuel‐Paul Sava, Zainab‐Aqeel Khan, Rolf W. Hügli, Michael T. Hirschmann   +4 more
wiley   +1 more source

TRIPS‐PLUS provisions in the economic partnership agreements with the EU: The CARIFORUM's experience and lessons for West Africa

The Journal of World Intellectual Property, Volume 27, Issue 2, Page 257-277, July 2024.
Abstract Negotiation for the Economic Partnership Agreement (EPA) between the European Union (EU) and six African, Caribbean and Pacific (APC) regions has been ongoing for over a decade. These negotiations are at different phases in the seven APC regions and have faced significant challenges, hindering ratification in most of them.
Juliet A. Ogbodo
wiley   +1 more source

Exploring Mercosur‐EU interregionalism: A multifaceted analysis of its past, present and future functions and dynamics

Contemporary European Politics, Volume 2, Issue 2, June 2024.
Abstract This article provides an analysis of the relationship between the Southern Common Market (Mercosur) and the European Union (EU) focusing on its purposes and functions, by exploring the literature on interregionalism through the perspectives of three distinct schools of thought: neorealism, neoliberal institutionalism and constructivism ...
María V. Alvarez
wiley   +1 more source

A América do Sul em movimento

Brazilian Journal of Political Economy, 2008
South America in movement. This paper discusses the prospects for the integration of South America, stressing that there are two competing projects.
Paulo Nogueira Batista Jr.
doaj   +1 more source