N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential
iNew Medicine, EarlyView.ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen +6 more
wiley +1 more source
The Study on the Capacitive Properties of Tungsten Oxide/Graphene Composites Prepared by Ultrasonic Spray Deposition. [PDF]
ACS OmegaLi CP, Su CC.
europepmc +1 more source
Do Linking‐Expression Substitutions Mitigate Deterministic Interpretations of Genetic Information?
Journal of Applied Philosophy, EarlyView.ABSTRACT It is a common concern that broader audiences interpret scientific information about the genetic correlates and causes of complex human traits in an overly deterministic manner. A frequently proposed way to address this issue is to carefully select the linking expressions used to describe gene–trait relationships when communicating genetic ...
Riin Kõiv
wiley +1 more source
Impact of variations in ALD procedure on nanomorphology, protecting properties and chemical stability of thin TiO<sub>2</sub> films. [PDF]
RSC AdvKrýsová H +4 more
europepmc +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang +4 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu +5 more
wiley +1 more source
Dysregulation of ERAD and Stress Response Proteins by V493F FTO Over-expression: A Proteomic Perspective. [PDF]
In VivoKanli A.
europepmc +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song +7 more
wiley +1 more source
RNA m<sup>6</sup>A modification is a driver and therapeutic target in gastric cancer. [PDF]
Cell Biol ToxicolChen Q, Lu H, Li D, Liu T.
europepmc +1 more source
Exploring the Impedance Spectroscopy in Hole‐Conductor‐Free Mesoscopic Perovskite Solar Cells
Progress in Photovoltaics: Research and Applications, EarlyView.This study employs impedance spectroscopy (IS) to investigate the carrier dynamics of printable perovskite solar cells (p‐MPSCs). The exceptional stability of p‐MPSCs enables reliable IS measurements under various conditions. We develop an equivalent circuit model to analyze the IS data, linking each circuit element to specific dynamic processes.
Cheng Qiu +5 more
wiley +1 more source