Results 1 to 10 of about 2,074 (109)

The association between variant rs9939609 in the FTO gene with free leptin index and the risk of obesity in the Indonesian children population

Egyptian Journal of Medical Human Genetics, 2022
Background Several studies have reported that fat mass and obesity-associated gene (FTO), especially the rs9939609 polymorphism, are associated with obesity and high leptin levels.
Miswar Fattah, Siska Mayasari Lubis
exaly   +2 more sources

FTO rs9939609 and rs17817449 polymorphisms contribute to metabolic syndrome risk by increasing triglyceride and glucose levels [PDF]

Frontiers in Genetics
Background and AimsThe polymorphisms in fat mass and obesity-associated gene (FTO) have been implicated in metabolic dysregulation. This study aimed to investigate the associations between the FTO rs9939609 and rs17817449 polymorphisms and MetS risk, and
Yongyan Song, Ting Wang, Mi Su, Xue Wang, Youjin Zhang, Jia Pan, Yunhan Wang, Jin Yang   +7 more
doaj   +2 more sources

Exploring the Association of FTO rs9939609 with Type 2 Diabetes, Fasting Glucose and HbA1c in a Southeastern Mexican Region of Predominant Mayan Genetic Background [PDF]

Biomolecules
Type 2 diabetes (T2D) is a multifactorial disease characterized by chronic hyperglycemia. The FTO variant rs9939609 has been widely associated with obesity, but emerging evidence suggests a broader role for T2D risk across diverse populations.
Nicolas Fragoso-Bargas, Litzy Naomi Toloza-Couoh, Irma Quintal-Ortiz, Guillermo Valencia-Pacheco, Nina Valadez-Gonzalez   +4 more
doaj   +2 more sources

Association of FTO rs9939609 polymorphism with serum leptin, insulin, adiponectin, and lipid profile in overweight adults

Adipocyte, 2020
FTO gene polymorphisms are associated with obesity and food intake. This study aimed to investigate the association of FTO rs9939609 polymorphism genotypes with serum glucose, lipid profile and serum hormones level. This cross-sectional study was carried
Mohammad Hassan Eftekhari, Maryam Gholamalizadeh, Mohammad Fararouei   +2 more
exaly   +2 more sources

A Cross‐Sectional Study Investigating the Relationship Between the FTO Gene Polymorphism in Relation to Obesity Traits and Vitamin D Status in Adolescence [PDF]

Obesity Science & Practice
Background and Objective Obesity affects 18%–25% of adolescents globally and represents a major public health challenge. Genetic factors contribute to obesity susceptibility, with the FTO gene variant rs9939609 consistently associated with obesity in ...
Ahmad Al‐Serri, Rabeah A. Al‐Temaimi, Abdullah Al‐Taiar, Lemia Shaban, Reem Al‐Sabah, Abdur Rahman, Ali H. Ziyab   +6 more
doaj   +2 more sources

Association of the FTO rs9939609 variant with glycemic control based on fasting glucose [PDF]

BMC Research Notes
Background Type 2 diabetes (T2D) affects 11.1% of the global population, underscoring the need for biomarkers that help characterize glycemic control status among treated individuals.
Nicolas Fragoso-Bargas, Rocio Vanessa Escarcega-Castro, Irma Quintal-Ortiz, Ligia Vera-Gamboa, Guillermo Valencia-Pacheco, Nina Valadez-Gonzalez   +5 more
doaj   +2 more sources

Breastfeeding moderates the relationship between fat mass and obesity-associated gene rs9939609 and body mass index among adolescents

Obesity Science and Practice, 2022
Objective Breastfeeding, which is important for early growth, is a possible moderator of genetic influence, such as the effect of the fat mass and obesity‐associated gene (FTO) on body mass index (BMI).
Cecilia Aslund, Sofia H Kanders, Kent W. Nilsson   +2 more
exaly   +2 more sources

Effects of FTO Gene rs9939609 and rs17817449 Polymorphisms on Insulin Resistance in Turkish Children With Obesity [PDF]

Journal of Diabetes
Backgrounds Fat mass and obesity‐related gene (FTO) has been associated with glucose homeostasis and insulin sensitivity in some populations. The aim of this study was to evaluate the association of FTO gene rs9939609 and rs17817449 polymorphisms with ...
Merve Köksal, Mehtap Ünlü Söğüt, Sevtap Kabalı   +2 more
doaj   +2 more sources

Hubungan antara polimorfisme gen Fat Mass Obesity Associated (FTO) rs9939609 dengan persentase lemak tubuh pada dewasa muda dengan obesitas sentral

JKS (Jurnal Kedokteran Syiah Kuala), 2023
Penelitian ini bertujuan untuk menganalisis hubungan polimorfisme gen FTO rs9939609 dengan persentase lemak tubuh pada dewasa muda dengan obesitas sentral pada mahasiswa kedokteran UNRI.
Nurhasanah Nurhasanah, Ulfah Ulfah
doaj   +1 more source

Association of FTO gene variant rs9939609 with hyperandrogenemia and fasting glucose levels in South Indian women with polycystic ovarian syndrome

Egyptian Journal of Medical Human Genetics, 2022
Background Polycystic ovary syndrome (PCOS) is a common endocrine–metabolic disorder due to genetic and environmental factors. Genetic variants located in intron 1 of Fat mass and obesity-associated (FTO) gene are associated with increased risk of ...
Zeinab Naghshband, Suttur S. Malini
doaj   +1 more source