Results 31 to 40 of about 2,096 (161)

The effect of FTO rs9939609 polymorphism on the association between colorectal cancer and dietary fiber

open access: yesFrontiers in Nutrition, 2022
BackgroundGene polymorphisms may explain the controversy on the association between colorectal cancer (CRC) and dietary fibers. The purpose of this study was to investigate the effect of fat mass and obesity-associated (FTO) rs9939609 polymorphism on the
Soroor Fathi   +12 more
doaj   +1 more source

The contribution of FTO rs9939609 and RETN rs1862513 polymorphisms in predisposing resettled indigenous (Orang Asli) Temiar to metabolic syndrome

open access: yesEgyptian Journal of Medical Human Genetics, 2023
Purpose Metabolic syndrome (MetS) is characterized by visceral obesity, elevated blood pressure and fasting blood glucose, increased triglycerides, and lower high-density lipoprotein cholesterol. MetS related with intricate gene-environment interactions.
Nur Sakinah Harun   +5 more
doaj   +1 more source

The age of developing diabetes and FTO polymorphisms (rs9939609, rs1421085, and rs9930506)

open access: yesEndokrynologia Polska, 2017
Type 2 diabetes (T2DM) is a common complex metabolic disorder that has a strong genetic predisposition. Fat mass and obesity-associated protein (FTO) is one of the genes of interest to us. Hypomethylation of a CpG site in the FTO gene was significantly associated with the risk of T2DM.
Władysław Grzeszczak   +8 more
openaire   +4 more sources

Common FTO rs9939609 variant and risk of type 2 diabetes in Palestine [PDF]

open access: yesBMC Medical Genetics, 2018
Genetic and environmental factors play a crucial role in the development of type 2 diabetes mellitus (T2DM) and obesity. This study aimed to investigate the association of the fat-mass and obesity-associated gene (FTO) rs9939609 variant with T2DM and body mass index (BMI) among Palestinian population.A total of 399 subjects were recruited, of whom 281 ...
Anas Sabarneh   +6 more
openaire   +4 more sources

ANALYSIS OF SINGLE NUCLEOTIDE POLYMORPHISM RS9939609 IN FTO GENE OF OBESE MALES IN IRAQI POPULATION

open access: yesThe Iraqi Journal of Medical Sciences, 2017
Background: Obesity is a serious on public health. It contributes in many serious health conditions including high cholesterol, type 2 diabetes, osteoarthritis, high blood pressure, gallbladder disease, coronary heart disease, stroke, respiratory ...
Mustafa N. Jumaa   +4 more
doaj   +4 more sources

Association analysis of FTO gene polymorphisms and obesity risk among Egyptian children and adolescents

open access: yesGenes and Diseases, 2017
Obesity is a common disorder that has a significant impact on human health as it may lead to many serious diseases and sometimes morbidity. Previous genome-wide association studies (GWAS) confirmed that there is a relationship between some variants in ...
Samar Samir Abdelmajed   +4 more
doaj   +1 more source

Association of FTO rs9939609 and CD36 rs1761667 with Visceral Obesity.

open access: yesJournal of nutritional science and vitaminology, 2020
In 2016, more than 1.9 billion adults were overweight; of which, over 650 million of adults were obese. Genetics and lifestyle play important roles in the development of obesity. Studies have shown that genetic variants contribute in developing obesity; such as FTO and CD36, which regulate metabolism and food preferences.
SALIM, Stephen   +2 more
openaire   +2 more sources

Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis [PDF]

open access: yesBMC Infectious Diseases, 2014
Obesity is known to affect cell-mediated immune responses. Recent studies have revealed that genetic polymorphisms in the fat mass and obesity associated (FTO) gene are related to human obesity. We hypothesize that this gene may also play a role in the risk of immune-related infectious diseases such as tuberculosis.This case-control study included 1625
Feng, Yan   +7 more
openaire   +2 more sources

The association between FTO rs9939609 gene polymorphism and anthropometric indices in adults [PDF]

open access: yesJournal of Physiological Anthropology, 2020
Abstract Background Fat mass and obesity-associated gene (FTO) is the most studied obesity-related gene up to date. We aimed to assess anthropometric indices in carriers of FTO rs9939609 polymorphism with overweight across Iranian population (Shiraz) to find out the associations of this polymorphism with obesity indices.
Mahsa Mehrdad   +3 more
openaire   +3 more sources

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