Results 21 to 30 of about 3,330 (137)

Inverse association between obesity predisposing FTO genotype and completed suicide. [PDF]

open access: yesPLoS ONE, 2014
The A allele of rs9939609 in the FTO gene predisposes to increased body mass index (BMI) and obesity. Recently we showed an inverse association between the obesity related A allele of rs9939609 and alcohol dependence which was replicated by others. Since
Izabela Chojnicka   +10 more
doaj   +1 more source

Association of FTO gene variants rs9939609 and rs1421085 with polycystic ovary syndrome

open access: yesEgyptian Journal of Medical Human Genetics, 2022
Background Polycystic ovary syndrome (PCOS) is among the most common complex genetic endocrinopathy, and its etiology and pathophysiology remain controversial.
Alaa A. Alnafjan   +4 more
doaj   +1 more source

Polimorfisme Gen FTO Rs9939609 Terhadap Konsentrasi Trigliserida Pada Subyek Obesitas Sentral [PDF]

open access: yes, 2023
Obesitas sentral merupakan keadaan bagian perut bagian tengah terdapat lemak yang berlebih. Penumpukan lemak berlebihan mengakibatkan peningkatan jumlah asam lemak bebas yang dihidrolisis LPL endotel.
Nurmaliana, Tati   +1 more
core   +1 more source

rs9939609 on Obesity

open access: yes, 2023
OBJECTIVE: The association between FTO rs9939609 and obesity is modified by physical activity (PA) and/or insulin sensitivity (IS). We aimed to assess whether these modifications are independent, whether PA and/or IS modify the association between ...
Malte Thodberg   +45 more
core   +1 more source

Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome : a systematic review and meta-analysis [PDF]

open access: yes, 2012
Aims/hypothesis FTO gene single nucleotide polymorphisms (SNPs) have been shown to be associated with obesity-related traits and type 2 diabetes. Several small studies have suggested a greater than expected effect of the FTO rs9939609 SNP on weight in ...
Lerchbaum, E.   +74 more
core   +1 more source

The contribution of FTO rs9939609 and RETN rs1862513 polymorphisms in predisposing resettled indigenous (Orang Asli) Temiar to metabolic syndrome

open access: yesEgyptian Journal of Medical Human Genetics, 2023
Purpose Metabolic syndrome (MetS) is characterized by visceral obesity, elevated blood pressure and fasting blood glucose, increased triglycerides, and lower high-density lipoprotein cholesterol. MetS related with intricate gene-environment interactions.
Nur Sakinah Harun   +5 more
doaj   +1 more source

Association between Common Variation at the FTO Locus and Changes in Body Mass Index from Infancy to Late Childhood: The Complex Nature of Genetic Association through Growth and Development [PDF]

open access: yes, 2011
An age-dependent association between variation at the FTO locus and BMI in children has been suggested. We meta-analyzed associations between the FTO locus (rs9939609) and BMI in samples, aged from early infancy to 13 years, from 8 cohorts of European ...
McCarthy, Mark I   +198 more
core   +2 more sources

ANALYSIS OF SINGLE NUCLEOTIDE POLYMORPHISM RS9939609 IN FTO GENE OF OBESE MALES IN IRAQI POPULATION

open access: yesThe Iraqi Journal of Medical Sciences, 2017
Background: Obesity is a serious on public health. It contributes in many serious health conditions including high cholesterol, type 2 diabetes, osteoarthritis, high blood pressure, gallbladder disease, coronary heart disease, stroke, respiratory ...
Mustafa N. Jumaa   +4 more
doaj   +4 more sources

Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample [PDF]

open access: yes, 2008
"Background: The rs9939609 T>A single-nucleotide polymorphism (SNP) in the FTO gene has previously been found to be associated with obesity in European Caucasian samples.
Harris, Stewart B.   +12 more
core   +1 more source

Association analysis of FTO gene polymorphisms and obesity risk among Egyptian children and adolescents

open access: yesGenes and Diseases, 2017
Obesity is a common disorder that has a significant impact on human health as it may lead to many serious diseases and sometimes morbidity. Previous genome-wide association studies (GWAS) confirmed that there is a relationship between some variants in ...
Samar Samir Abdelmajed   +4 more
doaj   +1 more source

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