Results 1 to 10 of about 2,549,001 (246)

Understanding the Fat Gene Obesity Common Variant FTO rs9939609

Pakistan Journal of Medicine and Dentistry
Obesity, attributable to the interaction of genetic makeup, lifestyle and environment Factors are a multifactorial disease. However, not all people with similar genetics or same environmental setup become obese.
Muhammad Haris Lucky, Saeeda Baig, Zil-e-Rubab   +2 more
doaj   +1 more source

Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

BMC Neuroscience, 2009
Background Polymorphism in the FTO gene is strongly associated with obesity, but little is known about the molecular bases of this relationship. We investigated whether hypothalamic FTO is involved in energy-dependent overconsumption of food.
Radomska Katarzyna J, Alsiö Johan, Stephansson Olga, Olszewska Agnieszka M, Fredriksson Robert, Olszewski Pawel K, Levine Allen S, Schiöth Helgi B   +7 more
doaj   +1 more source

Association of fatty acid-binding protein 2 and fat mass and obesity-associated gene polymorphism with primary open-angle glaucoma

Taiwan Journal of Ophthalmology, 2017
Purpose: The present study was carried out to investigate the association of fatty acid-binding protein 2 (FABP2) and fat mass and obesity-associated (FTO) gene polymorphism with primary open-angle glaucoma (POAG) cases and controls.
Shania Abbas, Syed Tasleem Raza, Anu Chandra, Luxmi Singh, Farzana Mahdi   +4 more
doaj   +1 more source

Protective Association of Single Nucleotide Polymorphisms rs1861868-FTO and rs7975232-VDR and Obesity in Saudi Females

International Journal of General Medicine, 2020
Lubna Ibrahim Al Asoom,1 Dina Tariq Al Afandi,2 Aseel Salah Al Abdulhadi,3 Nazish Rafique,1 Shahanas Chathoth,4 Ahmad A Al Sunni1 1Physiology Department, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Pediatrics ...
Al Asoom LI, Al Afandi DT, Al Abdulhadi AS, Rafique N, Chathoth S, Al Sunni AA   +5 more
doaj  

The relationship between fat mass and obesity-associated gene polymorphism and obesity among children in China: A systematic review and meta-analysis

International Journal of Noncommunicable Diseases, 2019
The fat mass and obesity-associated (FTO) gene has been shown to be associated with obesity in different populations. However, this association in the Chinese population has been controversial.
Zhiyong Dong, Sheikh Mohammed Shariful Islam, Ashley M Yu, Faraz Razi, Ramit Kumar Gupta, Mohammad Ali Moni, Cunchuan Wang   +6 more
doaj   +1 more source

Oxidative stress-mediated activation of FTO exacerbates impairment of the epithelial barrier by up-regulating IKBKB via N6-methyladenosine-dependent mRNA stability in asthmatic mice exposed to PM2.5

Ecotoxicology and Environmental Safety
In order to comprehend the underlying mechanisms contributing to the development and exacerbation of asthma resulting from exposure to fine particulate matter (PM2.5), we established an asthmatic model in fat mass and obesity-associated gene knockdown ...
Anying Xiong, Xiang He, Shengbin Liu, Qin Ran, Lei Zhang, Junyi Wang, Manling Jiang, Bin Niu, Ying Xiong, Guoping Li   +9 more
doaj   +1 more source

Association between Fat Mass and Obesity Associated (FTO) gene polymorphism (rs9939609) and lipid profile in type 2 diabetic obese Iraqi male

Iraq Medical Journal, 2018
Objective Investigation the risk of allele frequency of FTO gene polymorphism rs9939609 in obese male with type 2 diabetes mellitus (T2DM) and to examine the association of this polymorphism of FTO gene with BMI and lipid profile in obese Iraqi male ...
Fadhil Jawad Al-Tu’ma, Khamail Hassan Obed   +1 more
doaj  

FTO Gene Associates and Interacts with Obesity Risk, Physical Activity, Energy Intake, and Time Spent Sitting: Pilot Study in a Nigerian Population

Journal of Obesity, 2017
Fat mass and obesity-associated (FTO) gene influences obesity but studies have shown that environmental/lifestyle variables like physical activity (PA), time spent sitting (TSS), and energy intake might mediate the effect.
Bolaji Fatai Oyeyemi, Charles Ayorinde Ologunde, Ayonposi Bukola Olaoye, Nanfizat Abiket Alamukii   +3 more
doaj   +1 more source

Association of rs9939609 FTO Gene Polymorphism as a Risk Factor of Obesity in Adults

GHMJ (Global Health Management Journal)
Background: The cause of obesity is an imbalance between the number of calories taken and the amount burned. Obesity is a complex disease. The FTO rs9939609 gene polymorphism is one of the genetic factors that contribute to obesity in addition to ...
Tiar Masykuroh Pratamawati, Angel Angriani Elma Budai Sadji, Gara Samara Brajadenta, Donny Nauphar   +3 more
doaj   +1 more source

Association of FTO gene variant rs9939609 with polycystic ovary syndrome from Gujarat, India. [PDF]

BMC Med Genomics, 2023
Chaudhary H, Patel J, Jain NK, Panchal S, Laddha N, Joshi R.   +5 more
europepmc   +1 more source