Results 41 to 50 of about 2,549,001 (246)
Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies [PDF]
, 2014 Common intronic variants in the Human fat mass and obesity-associated gene (FTO) are found to be associated with an
increased risk of obesity. Overexpression of FTO correlates with increased food intake and obesity, whilst loss-of-function results in ...Rosa Maria Roccasecca (519728), Osborn Daniel P. S., Beales, PL, Daniel P. S. Osborn (519727), Fiona McMurray, Derek Stemple (183414), McMurray, F, Stemple Derek, Roccasecca, RM, Barroso, I, Philip L. Beales (492737), Osborn, DP, Inês Barroso (2144), Hernandez-Hernandez, V, Mukherjee, S, Derek Stemple, Cox, R, Philip L Beales, Victor Hernandez-Hernandez, Stemple, D, Sonia Christou-Savina (519731), Christou-Savina, S, Barroso Inês, Sriparna Mukherjee, Mukherjee Sriparna, Roccasecca Rosa Maria, Cox Roger, Sonia Christou-Savina, Hernandez-Hernandez Victor, Victor Hernandez-Hernandez (519729), Fiona McMurray (106290), Rosa Maria Roccasecca, Sriparna Mukherjee (519730), Beales Philip L., Daniel P S Osborn, Inês Barroso, McMurray Fiona, Osborn, DPS, Roger Cox, Christou-Savina Sonia, Roger Cox (73899) +40 morecore +1 more sourceInteraction between FTO rs9939609 and the Native American-origin ABCA1 rs9282541 affects BMI in the admixed Mexican population
BMC Medical Genetics, 2017 Background The aim of this study was to explore whether interactions between FTO rs9939609 and ABCA1 rs9282541 affect BMI and waist circumference (WC), and could explain previously reported population differences in FTO-obesity and FTO-BMI associations ...Marisela Villalobos-Comparán, Bárbara Antuna-Puente, María Teresa Villarreal-Molina, Samuel Canizales-Quinteros, Rafael Velázquez-Cruz, Paola León-Mimila, Hugo Villamil-Ramírez, Juan Antonio González-Barrios, José Luis Merino-García, María Rocío Thompson-Bonilla, Diego Jarquin, Osvaldo Erik Sánchez-Hernández, Martha Eunice Rodríguez-Arellano, Carlos Posadas-Romero, Gilberto Vargas-Alarcón, Francisco Campos-Pérez, Manuel Quiterio, Jorge Salmerón-Castro, Alessandra Carnevale, Sandra Romero-Hidalgo +19 moredoaj +1 more sourceAssociation between Common Variation at the FTO Locus and Changes in Body Mass Index from Infancy to Late Childhood: The Complex Nature of Genetic Association through Growth and Development [PDF]
, 2011 An age-dependent association between variation at the FTO locus and BMI in children has been suggested. We meta-analyzed associations between the FTO locus (rs9939609) and BMI in samples, aged from early infancy to 13 years, from 8 cohorts of European ...McCarthy, Mark I, Palmer, Colin N.A., Anneli Pouta, Yoav Ben-Shlomo, Warrington, N., Ann-Christine Syvänen, Cole, Tim, Mook-Kanamori, D.O. (Dennis), Lawrence Robert, Palmer, C., Vincent W V Jaddoe, Kaakinen, M, Palmer Lyle J., Palmer, Colin N. A., null null, Millwood, Iona Y., Laurent Briollais, Kaakinen, Marika, Tim J Cole, Johanna K Sandling, Palmer, Lyle, Palmer, CN, Davey Smith George, Craig E Pennell, Mook-Kanamori Dennis O., Briollais, L, Lawrence, R., Davey Smith, George, Palmer, Colin NA, Bennett, Amanda J, Palmer, Lyle J., Johanna K. Sandling, Timpson, Nicholas J, Nicole M. Warrington, Vincent W. V. Jaddoe, Sovio, U, Marika Kaakinen, Cole, Tim J, Palmer, C.N.A. (Colin), Jaddoe, Vincent W. V., Briollais, L., Amanda J. Bennett, Iona Y Millwood, Early Growth Genetics Consortium, Lawrence, R, Joanne Cecil, Cecil, J, Pouta, Anneli, Sandling, Johanna K., Smith, GD, Sovio, U. (Ulla), Lawrence, R.W. (Robert), Millwood, IY, Syvänen, Ann-Christine, Warrington, Nicole M., Timpson, Nicholas, Lawrie J. Beilin, Smith, G., Jaddoe, V., Cecil Joanne, Beilin, Lawrie J., Jarvelin, M-R, Craig E. Pennell, Laitinen Jaana, Nicole M Warrington, Mook-Kanamori, DO, Cole, T.J. (Tim), Mook-Kanamori, Dennis O., Järvelin Marjo-Riitta, et al., Pouta, A., Beilin, Lawrie J, McCarthy, MI, Lyle J Palmer, McCarthy Mark I., Pennell, Craig E., Mook-Kanamori, D., Warrington, N.M. (Nicole), Mark I. McCarthy, Davey Smith, G, Palmer Colin N. A., Cole, TJ, Warrington, Nicole M, Briollais Laurent, Molitor John, Jaddoe Vincent W. V., Pennell, C.E. (Craig), Briollais, Laurent, Dennis O. Mook-Kanamori, McCarthy, Mark I., John Molitor, for the EGG, Consortium, Palmer C N, A, Briollais, L. (Laurent), George Davey Smith, Jaddoe, VW, Jaddoe, VWV, Warrington Nicole M., Timpson, NJ, Molitor, J. (John), Nicholas J Timpson, Pennell, CE, Nicholas J. Timpson, Pennell, Craig E, Bennett, A.J. (Amanda), Dennis O Mook-Kanamori, Laitneen, J., Pouta, A, Sandling, JK, Molitor, J., Järvelin, Marjo-Riitta, Syvänen Ann-Christine, Cecil, Joanne Elizabeth, Millwood, Iona, Cole, Tim J., Smith, George Davey, McCarthy, Mark, Laitinen, J, Colin N. A. Palmer, Colin N A Palmer, Ben-Shlomo, Yoav, Jaana Laitinen, Kaakinen Marika, Sovio, U., Palmer, Lyle J, Robert Lawrence, Pennell Craig E., Kaakinen, M., Lawrence, Robert, Bennett, Amanda, Amanda J Bennett, Palmer, L., Jaddoe, Vincent WV, Sandling, J.K. (Johanna), Iona Y. Millwood, Beilin, Lawrie, Syvänen, Ann-Christine,, Mook-Kanamori, Dennis O, Pouta Anneli, Syvänen, A.-C., Bennett Amanda J., Sandling, J., Jaddoe, V.W.V. (Vincent), Sandling, Johanna K, Sovio Ulla, Beilin, LJ, Cecil, J., Bennett, Amanda J., Molitor, J, Palmer, LJ, Ben-Shlomo, Y., Lyle J. Palmer, Jaddoe, Vincent, Millwood, I., Beilin, L., Syvanen, A-C, Timpson Nicholas J., Jarvelin, MR, Bennett A, J, Järvelin, M.R., Sandling, Johanna, Lawrie J Beilin, Ben-Shlomo, Y, Beilin, L.J. (Lawrence), Syvanen, Ann-Christin, Bennett, AJ, Millwood, Iona Y, Laitinen, Jaana, Ulla Sovio, Bennett, A., Sovio, Ulla, Laitinen, J. (Jaana), Tim J. Cole, Millwood Iona Y., Timpson, Nicholas J., Smith, A.V. (Davey), Palmer, CNA, Cole Tim J., Mark I McCarthy, Mook, Dennis, McCarthy M, I, Cecil, Joanne, Pouta, A. (Anneli), Timpson, N.J. (Nicholas), Millwood, I.Y. (Iona), Beilin Lawrie J., Syvanen, A., Molitor, John, Pennell, Craig, Sandling Johanna K., Cecil, J. (Joanne), Sandling, Johanna K.,, Kaakinen, M. (Marika), Marjo-Riitta Järvelin, Warrington, NM, Ben-Shlomo Yoav, McCarthy, M.I. (Mark), Syvanen, AC, Palmer, Colin N. A.; id_orcid +198 morecore +2 more sourcesNovel AlkB Dioxygenases – Alternative Models for In Silico and In Vivo Studies [PDF]
, 2012 Background: ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly ...Mielecki, Marcin, Marcin Grynberg, Zugaj, Dorota Łucja, Anna Muszewska, Jadwiga Nieminuszczy, Mielecki Marcin, Marcin Grynberg (183714), Marcin Mielecki (186643), Mielecki, Damian, Jan Piwowarski (186640), Dorota Ł. Zugaj (186635), Mielecki Damian, Piwowarski Jan, Grzesiuk Elżbieta, Grzesiuk, Elzbieta, Marcin Mielecki, Nieminuszczy, Jadwiga, Zugaj Dorota Ł., Damian Mielecki (186634), Chojnacka, Aleksandra, Grynberg Marcin, Dorota Ł Zugaj, Grynberg, Marcin, Nieminuszczy Jadwiga, Jan Piwowarski, Muszewska Anna, Jadwiga Nieminuszczy (186644), Muszewska, Anna, Aleksandra Chojnacka (186642), Piwowarski, Jan, Chojnacka Aleksandra, Damian Mielecki, Aleksandra Chojnacka, Elżbieta Grzesiuk (186645), Elżbieta Grzesiuk, Anna Muszewska (186638) +35 morecore +2 more sourcesAssociations between BMI and the FTO Gene Are Age Dependent: Results from the GINI and LISA Birth Cohort Studies up to Age 6 Years [PDF]
, 2010 Objective: The association between polymorphisms in intron 1 of the fat mass and obesity associated gene (FTO) and obesity-related traits is one of the most robust associations reported for complex traits and is established both in adults and children ...Wichmann, Heinz-Erich, Schaaf, Beate, Ursula Krämer, Rzehak, P., André Scherag, Stefanie Sausenthaler, Olf Herbarth, Hebebrand, J., Carl Peter Bauer, Illig, Thomas, Sausenthaler, S., Peter Rzehak, Borte, Michael, Joachim Heinrich, Andrea von Berg, Heinrich, Joachim, Bauer, Carl Peter, Harald Grallert, Thomas Illig, Herbarth, O., von Berg, A., Berdel, D., Schaaf, B., Heinrich, J., Sausenthaler, Stefanie, Hebebrand, Johannes, Koletzko, Sibylle, Michael Borte, H.-Erich Wichmann, Rzehak, Peter, Scherag, Andre, Grallert, Harald, Wichmann, H.-E., Krämer, Ursula, Bauer, C.P., Illig, T., Berg, Andrea von, Dietrich Berdel, Grallert, H., Borte, M., Berdel, Dietrich, Johannes Hebebrand, Koletzko, S., Krämer, U., Scherag, A., Herbarth, Olf, Beate Schaaf, Sibylle Koletzko, Rzehak, P;Scherag, A;Grallert, H;Sausenthaler, S;Koletzko, S;Bauer, CP;Schaaf, B;von Berg, A;Berdel, D;Borte, M;Herbarth, O;Kramer, U;Illig, T;Wichmann, HE;Hebebrand, J;Heinrich, J, Rzehak, Peter;Scherag, Andr'e;Grallert, Harald;Sausenthaler, Stefanie;Koletzko, Sibylle;Bauer, Carl Peter;Schaaf, Beate;Berg, Andrea von;Berdel, Dietrich;Borte, Michael;Herbarth, Olf;Krämer, Ursula;Illig, Thomas;Wichmann, H.-Erich;Hebebrand, Johannes;Heinrich, Joachim +49 morecore +1 more sourceAssessment of the FTO gene polymorphisms inmale patients with metabolic syndrome [PDF]
Advances in Clinical and Experimental Medicine, 2018 Accumulating evidence indicates the potential involvement of the FTO gene polymorphisms in the etiology of metabolic syndrome (MetS) and related disorders.In this study, we aimed to investigate whether the FTO gene polymorphisms are associated with the risk of MetS and its simple components in a homogeneous sample of males.Anthropometric and ...Ryszard, Ślęzak, Przemysław, Leszczyński, Magdalena, Warzecha, Łukasz, Łaczmański, Błażej, Misiak +4 moreopenaire +3 more sourcesAssociation of the FTO gene with obesity and cancer in dogs
Journal of Istanbul Veterinary Sciences, 2023 Nowadays, obesity is one of the most serious problems that significantly affect health in both human and animal populations. Fat mass and obesity-associated gene (FTO), increases the risk of obesity and other metabolic diseases such as cancer, with taking part in many complex molecular pathways.Dina BEDİK, Gizem KIRMIZIOĞLU, Iraz AKIŞ +2 moreopenaire +2 more sourcesTwo New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups [PDF]
, 2010 Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents.Marjo-Riitta Jarvelin, Martin Klingenspor, Heude, Barbara, Lévy-Marchal, C., Wichmann HE, Balkau, B, Hebebrand, J., Schürmann, A., Kiess, W., Fromme Tobias, Hartikainen, A.L., Rosskopf D, Erbel, R., Schulz N, Klingenspor Martin, Wichmann, H.-E., Schäfer H, Illig Thomas, Joeckel, Karl-Heinz, Fisher E, Johannes Hebebrand, Vogel, Carla I. G., Schulz, N, Jacques Weill, Hartikainen Anna-Liisa, Körner, A, Nöthen, MM, Krude Heiko, Borte, M, Scherag André, Froguel Philippe, Winfried Rief, Hinney A, Nöthen, M.M., Klingenspor, Martin, Hartikainen AL, Boeing Heiner, Schaefer, Helmut, Schulz, N., Rayner, Nigel W., Borte, Michael, Balkau, B., Rosskopf Dieter, Moebus, Susanne, Heinrich, Joachim, Harald Grallert, Hebebrand J, Heinrich, J., Thomas W Mühleisen, Rzehak, Peter, Klingenspor, M, Scherag S, Grallert, H., Hinney, A., Fromme, T., Vogel CI, Moebus, S, Rayner NW, Erbel, R, Dieter Rosskopf, Reinehr, T., Hartikainen, Anna-Liisa, Scherag A, Vogel, CIG, Eva Fisher, Jarvelin, Marjo-Riitta, Hartikainen, AL, Biebermann, Heike, Mühleisen TW, Vatin, V, Noethen, Markus M., Nigel W Rayner, Wichmann, H-E, Grallert H, Inga Prokopenko, Dina, C., Jarick Ivonne, Rief W, Vogel, CI, Mueller, Timo D., Prokopenko I, Berdel Dietrich, David Meyre, Berdel, D., Jarvelin, M.R., Hebebrand, Johannes, Borte Michael, Reinehr, T, Schulz Nadja, Grallert, Harald, Jarvelin, M-R, Vatin, Vincent, Joeckel, K-H, Schaefer, H, Meyre D, Jarvelin MR, Fisher Eva, Boes Tanja, Heude, B, Fisher, E, Levy-Marchal, Claire, Heiko Krude, Vogel, C.I.G., Borte M, McCarthy, MI, Koerner, Antje, Karl-Heinz Jöckel, McCarthy Mark I., Boeing H, Noethen, MM, Erbel, Raimund, Wichmann, HE, Heinrich, J, Illig T, Peter Rzehak, Jarvelin Marjo-Riitta, Mýhleisen TW, Grallert Harald, Thomas Illig, Weill, J, Levy-Marchal, C, Heude Barbara, Kovacs Peter, Jöckel, KH, Kovacs, P, Heude B, Prokopenko, Inga, Meyre, David, Rzehak Peter, Fromme, Tobias, Vogel Carla I. G., McCarthy, Mark I., Krude, H, Berdel, D, Kiess, W, Mühleisen Thomas W., Rief, W., Froguel P, Boeing, Heiner, Claire Levy-Marchal, McCarthy MI, Biebermann H, Illig, T, Mueller, TD, Christian Rimmbach, Scherag Susann, Tanja Boes, Carla I G Vogel, Vatin, V., Fisher, Eva, Heude, B., Prokopenko, I, Heike Biebermann, Reinehr Thomas, Hinney, A, Ivonne Jarick, Heiner Boeing, Christian Dina, Moebus, S., Delplanque J, Kovacs, P., Dina Christian, Fromme T, Illig, T., Weill, Jacques, Rosskopf, Dieter, Fisher, E., Reinehr, Thomas, Jöckel KH, Boes, T, Nadja Schulz, Kovacs, Peter, Moebus S, Schýrmann A, Muehleisen, TW, Heinrich Joachim, Raimund Erbel, Rosskopf, D., Prokopenko, I., Körner Antje, Scherag, Susann, Rimmbach, Christian, Dina C, Antje Körner, Koerner, A, Hebebrand, J, Scherag, S., Scherag, A, Rzehak, P., Thomas Reinehr, Rief, Winfried, Boeing, H, Reinehr T, Klingenspor M, Helmut Schäfer, Scherag, S, Schäfer, H, H-Erich Wichmann, Schäfer, H., Hebebrand Johannes, Meyre David, Rayner, N.W., Kiess, Wieland, Anke Hinney, Hinney Anke, Scherag, Andre, Meyre, D, Rosskopf, D, Hinney, Anke, Biebermann, H., Susanne Moebus, Körner A, Scherag, A., Levy-Marchal C, Müller, T.D., Delplanque, Jerome, Rief Winfried, Muehleisen, Thomas W., Müller TD, Krude, H., Rimmbach, C, Jöckel, K.-H., Rzehak P, Berdel D, Philippe Froguel, Biebermann, H, Wichmann, Heinz-Erich, Rief, W, Anna-Liisa Hartikainen, Barbara Heude, McCarthy, M.I., Jarvelin, MR, André Scherag, Jérôme Delplanque, Rayner, NW, Boes, T., Jarick I, Beverley Balkau, Rimmbach, C., Mühleisen, T.W., Mühleisen, TW, Vatin Vincent, Vincent Vatin, Hartikainen, A-L, Moebus Susanne, Schürmann, A, Delplanque, J, Michael Borte, Balkau, Beverley, Susann Scherag, Boes T, Balkau Beverley, Jarick, Ivonne, Boes, Tanja, Müller, TD, Prokopenko Inga, Borte, M., Annette Schürmann, Krude H, Berdel, Dietrich, Nöthen Markus M., Jarick, I, Müller Timo D., Schulz, Nadja, Wichmann H.-Erich, Dina, Christian, Dina, C, Mýller TD, Froguel, Philippe, Weill Jacques, Fromme, T, Rimmbach C, Grallert, H, Schuermann, Annette, Mark I McCarthy, Schäfer Helmut, Weill, J., Delplanque Jérôme, Rayner Nigel W., Kiess Wieland, Illig, Thomas, Timo D Müller, Joachim Heinrich, Balkau B, Vatin V, Tobias Fromme, Rzehak, P, Schürmann Annette, Kiess W, Körner, A., Nöthen MM, Levy-Marchal Claire, Kovacs P, Markus M Nöthen, Erbel Raimund, Wieland Kiess, Erbel R, Heinrich J, Dietrich Berdel, Klingenspor, M., Jarick, I., Schürmann A, Rimmbach Christian, Boeing, H., Froguel, P., Peter Kovacs, Krude, Heiko, Weill J, Schuermann, A, Delplanque, J., Jöckel Karl-Heinz, Biebermann Heike, Meyre, D., Froguel, P, Scherag, A., Dina, C., Hinney, A., Vatin, V., Scherag, S., Vogel, C.I.G., Müller, T.D., Grallert, H., Wichmann, H.-E., Balkau, B., Heude, B., Jarvelin, M.-R., Hartikainen, A.-L., Levy-Marchal, C., Weill, J., Delplanque, J., Körner, A., Kiess, W., Kovacs, P., Rayner, N.W., Prokopenko, I., McCarthy, M.I., Schäfer, H., Jarick, I., Boeing, H., Fisher, E., Reinehr, T., Heinrich, J., Rzehak, P., Berdel, D., Borte, M., Biebermann, H., Krude, H., Rosskopf, D., Rimmbach, C., Rief, W., Fromme, T., Klingenspor, M., Schürmann, A., Schulz, N., Nöthen, M.M., Mühleisen, T.W., Erbel, R., Jöckel, K.-H., Moebus, S., Boes, T., Illig, T., Froguel, P., Hebebrand, J., Meyre, D. +314 morecore +1 more source
