Fat Mass and Obesity-Associated Gene (FTO) in Eating Disorders: Evidence for Association of the rs9939609 Obesity Risk Allele with Bulimia nervosa and Anorexia nervosa [PDF]
Objective: The common single nucleotide polymorphism (SNP) rs9939609 in the fat mass and obesity-associated gene (FTO) is associated with obesity. As genetic variants associated with weight regulation might also be implicated in the etiology of eating ...
André Scherag +66 more
core +4 more sources
FTO gene polymorphisms and hepatoblastoma susceptibility among Chinese children
Current knowledge on the etiology of hepatoblastoma remains limited. FTO gene has been documented as a susceptibility gene for several types of cancer. However, its role has not been characterized in hepatoblastoma. Herein, we intended to explore whether FTO gene single nucleotide polymorphisms (SNPs) contribute to the risk of hepatoblastoma.
Junzhen Fan +11 more
openaire +2 more sources
Background The aim of this study was to explore whether interactions between FTO rs9939609 and ABCA1 rs9282541 affect BMI and waist circumference (WC), and could explain previously reported population differences in FTO-obesity and FTO-BMI associations ...
Marisela Villalobos-Comparán +19 more
doaj +1 more source
Freedom-to-Operate in the Crop Sciences: Procedure [PDF]
Freedom to operate (FTO) is the ability to proceed with research, development and commercialization of a crop science product, while fully accounting for any potential risks of infringing activity, that is, whether a product can be made, used, sold ...
Kowalski, Stanley P.
core +2 more sources
The role of FTO genotype in the effect of FTO gene expression level on change in body mass index and body composition has not been studied. This study aimed to investigate the role of FTO genotype in the association between change in the expression level
Saeid Doaei +12 more
doaj +1 more source
Associations between BMI and the FTO Gene Are Age Dependent: Results from the GINI and LISA Birth Cohort Studies up to Age 6 Years [PDF]
Objective: The association between polymorphisms in intron 1 of the fat mass and obesity associated gene (FTO) and obesity-related traits is one of the most robust associations reported for complex traits and is established both in adults and children ...
Bauer, Carl Peter +15 more
core +1 more source
Effect of FTO Expression and Polymorphism on Fat Deposition in Suzhong Pigs [PDF]
Fat mass and obesity associated gene (FTO) plays an important role in appetite control and energy consumption in human and mice. In order to examine FTO expression influence on fat deposition in Suzhong pigs, FTO mRNA expression was detected in 16 ...
Yanfeng Fu, Lan Li, Shouwen Ren
doaj +1 more source
m6a RNA methylation: the implications for health and disease [PDF]
The recent resurgence of interest in m6a has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification.
McGuinness, D., Mcguinness, D.H.
core +1 more source
A Systematic Mapping Approach of 16q12.2/FTO and BMI in More Than 20,000 African Americans Narrows in on the Underlying Functional Variation: Results from the Population Architecture using Genomics and Epidemiology (PAGE) Study [PDF]
Genetic variants in intron 1 of the fat mass- and obesity-associated (FTO) gene have been consistently associated with body mass index (BMI) in Europeans.
A Adeyemo +88 more
core +8 more sources
The IRX3 gene; the missing link between the FTO gene and obesity
Aims: The aim of this study was investigation of the mediator role of the IRX3 gene in the relationship between the FTO gene and obesity. Materials and Methods: All related articles published in English from June 1990 to February 2017 were studied ...
maryam gholamalizadeh +4 more
doaj +1 more source

