Results 21 to 30 of about 7,322,114 (249)
Understanding the Fat Gene Obesity Common Variant FTO rs9939609
Pakistan Journal of Medicine and DentistryObesity, attributable to the interaction of genetic makeup, lifestyle and environment Factors are a multifactorial disease. However, not all people with similar genetics or same environmental setup become obese.
Muhammad Haris Lucky +2 more
doaj +1 more source
FTO gene and its impact upon obesity
Dietetician.ro, 2023 Roxana Ciocâltea
semanticscholar +2 more sources
FTO gene variants and consumption of alcoholic beverages [PDF]
Alcoholism and Drug Addiction, 2020 The aim of this review is to present the role of FTO gene sequence variation in determining predisposition to specific forms of alcohol consumption. This systematic review includes studies published in 2011-2013 and 2019 from the PubMed, Science Direct and Wiley Online Library databasis.
Anna Karolina Flaga +2 more
openaire +3 more sources
Association of the FTO Gene With BMI [PDF]
Obesity, 2008 Variants in the FTO gene have been strongly associated with obesity in a very large sample (38,759) of diabetic and control subjects. To replicate these findings, the previously reported SNP in the FTO gene (rs9939609, T/A) was genotyped in 5,607 subjects from five different Utah studies.
Steven C, Hunt +7 more
openaire +2 more sources
Journal of Translational Medicine, 2021 Background The roles of FTO gene and the level of serum 25-OH-vitamin D in obesity are frequently reported. This study aimed to investigate the interactions of serum 25-OH-vitamin D level, FTO and IRX3 genes expression, and FTO genotype in obese and ...
Maryam Gholamalizadeh +12 more
doaj +1 more source
Fat mass and obesity associated gene (FTO) expression is regulated negatively by the transcription factor Foxa2. [PDF]
PLoS ONE, 2012 Fat mass and obesity associated gene (FTO) is the first gene associated with body mass index (BMI) and risk for diabetes. FTO is highly expressed in the brain and pancreas, and is involved in regulating dietary intake and energy expenditure.
Jianjin Guo +8 more
doaj +1 more source
Acta Diabetologica, 2021 Gestational diabetes mellitus (GDM) can lead to short- and long-term complications for the child. Epigenetic alterations could contribute to explaining the metabolic disturbances associated with foetal programming.
M. Franzago +7 more
semanticscholar +1 more source
FTO Suppresses STAT3 Activation and Modulates Proinflammatory Interferon-Stimulated Gene Expression [PDF]
Journal of Molecular Biology, 2021 AbstractSignaling initiated by type I interferon (IFN) results in the induction of hundreds of IFN-stimulated genes (ISGs). The type I IFN response is important for antiviral restriction, but aberrant activation of this response can lead to inflammation and autoimmunity. Regulation of this response is incompletely understood.
Michael J. McFadden +6 more
openaire +2 more sources
The FTO gene and measured food intake in children [PDF]
International Journal of Obesity, 2008 Polymorphisms in the obesity-associated gene, FTO, have been linked with sensitivity to satiety in children, indicating FTO may be influencing one of the regulatory drivers underlying food intake. In this study, we tested the hypothesis that food intake in a standard eating behaviour paradigm in which palatable food is offered under conditions of ...
Wardle, J. +3 more
openaire +3 more sources
FTO gene polymorphisms and obesity risk: a meta-analysis [PDF]
BMC Medicine, 2011 Abstract Background The pathogenesis of obesity is reportedly related to variations in the fat mass and an obesity-associated gene (FTO); however, as the number of reports increases, particularly with respect to varying ethnicities, there is a need to determine more precisely the effect sizes in each ethnic group.
Li Xiaobo +5 more
openaire +3 more sources