Results 31 to 40 of about 15,826 (205)
Assessment of the FTO gene polymorphisms inmale patients with metabolic syndrome [PDF]
Advances in Clinical and Experimental Medicine, 2018 Accumulating evidence indicates the potential involvement of the FTO gene polymorphisms in the etiology of metabolic syndrome (MetS) and related disorders.In this study, we aimed to investigate whether the FTO gene polymorphisms are associated with the risk of MetS and its simple components in a homogeneous sample of males.Anthropometric and ...
Ryszard, Ślęzak +4 more
openaire +3 more sources
Effect of FTO Expression and Polymorphism on Fat Deposition in Suzhong Pigs [PDF]
Asian-Australasian Journal of Animal Sciences, 2013 Fat mass and obesity associated gene (FTO) plays an important role in appetite control and energy consumption in human and mice. In order to examine FTO expression influence on fat deposition in Suzhong pigs, FTO mRNA expression was detected in 16 ...
Yanfeng Fu, Lan Li, Shouwen Ren
doaj +1 more source
Association of the FTO gene with obesity and cancer in dogs
Journal of Istanbul Veterinary Sciences, 2023 Nowadays, obesity is one of the most serious problems that significantly affect health in both human and animal populations. Fat mass and obesity-associated gene (FTO), increases the risk of obesity and other metabolic diseases such as cancer, with taking part in many complex molecular pathways.
Dina BEDİK +2 more
openaire +2 more sources
The IRX3 gene; the missing link between the FTO gene and obesity
Asian Pacific Journal of Cancer Biology, 2017 Aims: The aim of this study was investigation of the mediator role of the IRX3 gene in the relationship between the FTO gene and obesity. Materials and Methods: All related articles published in English from June 1990 to February 2017 were studied ...
maryam gholamalizadeh +4 more
doaj +1 more source
Association of FTO gene with obesity in Polish schoolchildren [PDF]
Anthropological Review, 2014 The goal of the study was verification of fat mass and obesity-associated (FTO) gene polymorphisms as significant risk factors of obesity in the population of Polish children. Body mass index (BMI) and DNA were evaluated, where DNA was extracted from saliva, collected from 213 children at the age of 6–13 years. DNA was genotyped by PCR ...
Sitek, A. +5 more
openaire +3 more sources
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.
PLoS Genetics, 2009 Human FTO gene variants are associated with body mass index and type 2 diabetes. Because the obesity-associated SNPs are intronic, it is unclear whether changes in FTO expression or splicing are the cause of obesity or if regulatory elements within ...
Chris Church +12 more
doaj +1 more source
Impact of variation at the FTO locus on milk fat yield in Holstein dairy cattle. [PDF]
PLoS ONE, 2013 This study explores the biological role of the Fat Mass and Obesity associated (FTO) gene locus on milk composition in German Holstein cattle. Since FTO controls energy homeostasis and expenditure and the FTO locus has repeatedly shown association with ...
Lea G Zielke +5 more
doaj +1 more source
Relationship between the hsa miR 150-5p and FTO gene expression in white subcutaneous adipose tissue with overweight/obesity, lipid profile and glycemia [PDF]
Anais da Academia Brasileira de Ciências, 2020 The overweight population is growing in the world, and the search for obesity-associated mechanisms is important for a better understanding of this disease. Few studies with the FTO gene and miRs show how they associate to obesity and how they can impact
VITOR N. MORAES +6 more
doaj +1 more source
PLoS ONE, 2010 Sequence variants in the first intron of FTO are strongly associated with human obesity and human carriers of the risk alleles show evidence for increased appetite and food intake. Mice globally lacking Fto display a complex phenotype characterised by both increased energy expenditure and increased food intake.
Tung, Yi-Chun Loraine +6 more
openaire +6 more sources
PLoS ONE, 2018 BackgroundSingle-nucleotide polymorphisms (SNPs), which are located in the first intron of the FTO gene, are reported to be associated with body weight and the body mass index (BMI).
Naser Kalantari +10 more
doaj +1 more source