Results 31 to 40 of about 7,322,114 (249)
Association of FTO gene variants rs9939609 and rs1421085 with polycystic ovary syndrome
Egyptian Journal of Medical Human Genetics, 2022 Background Polycystic ovary syndrome (PCOS) is among the most common complex genetic endocrinopathy, and its etiology and pathophysiology remain controversial.
Alaa A. Alnafjan +4 more
doaj +1 more source
Ginekologia Polska, 2021 OBJECTIVES Polycystic ovary syndrome (PCOS) is a complex reproductive endocrinopathy among reproductive-aged women and related with body mass and insulin resistance.
Fatma Beyazıt +3 more
semanticscholar +1 more source
The obesity-associated Fto gene is a transcriptional coactivator [PDF]
Biochemical and Biophysical Research Communications, 2010 The fat mass and obesity associated, FTO, gene has been shown to be associated with obesity in human in several genome-wide association scans. In vitro studies suggest that Fto may function as a single-stranded DNA demethylase. In addition, homologous recombination-targeted knockout of Fto in mice resulted in growth retardation, loss of white adipose ...
Qiong, Wu +4 more
openaire +2 more sources
The role of the FTO gene in the relationship between depression and obesity. A systematic review.
Neuroscience and Biobehavioral Reviews, 2021 Depression and obesity are major global health problems that frequently co-occur. The FTO gene has one of the strongest links with obesity and high body mass index (BMI) in humans.
J. A. Zarza-Rebollo +2 more
semanticscholar +1 more source
Association between FTO gene polymorphism and obesity in down syndrome children. [PDF]
Eur J PediatrAbstract Children with Down syndrome (DS) have a higher incidence of overweight and obesity compared to typically developing peers. The fat mass and obesity-associated gene (FTO) is one of the early identified genes linked to obesity in various populations.
Mourad SA +6 more
europepmc +3 more sources
The association between FTO rs9939609 polymorphism and serum lipid profile in adult women
Diabetology & Metabolic Syndrome, 2021 Background FTO gene is considered to play an important role in many metabolic diseases. Evidence from studies indicated the possible association between the FTO rs9939609 polymorphisms with serum lipid profile.
Vahideh Jalili +10 more
doaj +1 more source
Detection of Rs9939609 Polymorphism of Fto Gene and Rs324011 Polymorphism of Stat6 Gene and Severity Degree of Bronchial Asthma Associated with Obesity [PDF]
, 2017 The aim of this research was to analyze the distribution of FTO and STAT6 genes polymorphism in patients with bronchial asthma (BA), associated with obesity (Ob) depending on the main disease severity degree.Materials and methods.
Fediv, A. (Alexander) +1 more
core +2 more sources
Eating behaviours and food cravings; influence of age, sex, BMI and FTO genotype [PDF]
, 2019 Previous studies indicate that eating behaviours and food cravings are associated with increased BMI and obesity. However, the interaction between these behaviours and other variables such as age, sex, BMI and genetics is complex.
Caroline Dalton +5 more
core +1 more source
PLoS Genetics, 2007 The obesity epidemic is responsible for a substantial economic burden in developed countries and is a major risk factor for type 2 diabetes and cardiovascular disease.
A. Scuteri +24 more
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 ObjectiveThe m6A methylation was involved in the pathogenesis of pulmonary tuberculosis (PTB), and our study aimed to reveal the potential association of m6A demethylase (ALKBH5, FTO) genes variation, expression levels and PTB.MethodsEight SNPs (ALKBH5 ...
Tian-Ping Zhang +3 more
doaj +1 more source