Results 1 to 10 of about 114,072 (158)
Dificuldades e desafios para a educação sexual em uma escola técnica do Tocantins
Revista Sítio Novo, 2023 No âmbito da educação sexual, a escola e os educadores têm papel fundamental, podendo contribuir positivamente para uma educação integral, social e culturalmente libertadora, em que o conhecimento ultrapasse a técnica e o conteúdo dos currículos das ...
ALINE DE SOUSA SILVA +3 more
doaj +1 more source
FTO promotes liver inflammation by suppressing m6A mRNA methylation of IL-17RA
Frontiers in Oncology, 2022 BackgroundPrevious studies have demonstrated that inflammation-related interleukin-17 (IL-17) signaling plays a pivotal role in the pathogenesis of non-alcoholic steatohepatitis (NASH)- and alcoholic liver disease (ALD)-induced hepatocellular carcinoma ...
Xiaojie Gan +10 more
doaj +1 more source
Lifestyle Genomics, 2023 Introduction: Single-nucleotide polymorphism (SNP) rs9939609 in the FTO gene has been associated with dietary intake and appetite traits, mainly in participants with obesity; however, it remains widely unexplored in normal weight participants.
Andrea Madrigal-Juarez +7 more
doaj +1 more source
Epigenetics, 2022 Pancreatic cancer (PC) is one of the most fatal cancers with a very poor prognosis. Here, we found that N6-methyladenosine (m6A) RNA demethylase fat mass and obesity-related protein (FTO) promote the growth, migration and invasion of PC.
Wei Wang +7 more
doaj +1 more source
Archives of Medical Science, 2020 Introduction Type 2 diabetes mellitus (T2DM) is known as one of the most common metabolic diseases and FTO polymorphism has been implicated in the susceptibility to this disease.
Seyedahmad Hosseini +4 more
doaj +1 more source
Атеросклероз, 2022 Aim of the study was to investigate the associations of polymorphisms of some genes with overweight and some anthropometric and biochemical indicators in a population sample of the young population of Novosibirsk. Material and methods.
Diana V. Denisova +2 more
doaj +1 more source
Freedom-to-Operate in the Crop Sciences: Procedure [PDF]
, 2004 Freedom to operate (FTO) is the ability to proceed with research, development and commercialization of a crop science product, while fully accounting for any potential risks of infringing activity, that is, whether a product can be made, used, sold ...
Kowalski, Stanley P.
core +2 more sources
Genes and molecules related to obesity and lifestyle-related disease and exercise
Journal of Physical Fitness and Sports Medicine, 2013 In 2006, Rankinen et al. reported 127 candidate obesity-related genes, and since then more have been identified (http://www.genome.gov/gwastudies/). A lot of mutations in more than 7 genes, especially in the MC4-R gene, were reported as monogenic obesity
Masaki Kimura
doaj +1 more source
Associations between BMI and the FTO Gene Are Age Dependent: Results from the GINI and LISA Birth Cohort Studies up to Age 6 Years [PDF]
, 2010 Objective: The association between polymorphisms in intron 1 of the fat mass and obesity associated gene (FTO) and obesity-related traits is one of the most robust associations reported for complex traits and is established both in adults and children ...
Bauer, Carl Peter +15 more
core +1 more source
Epigenetics, 2023 N6-Methyladenosine (m6A) plays a key role in the occurrence and development of various cancers. Fat mass and obesity‐associated protein (FTO) was is involved in multiple cancers owing to its demethylase activity, and the molecular mechanism underlying ...
Zhuang Sun +5 more
doaj +1 more source