Results 31 to 40 of about 26,295 (268)

FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner

open access: yesEpigenetics, 2023
N6-Methyladenosine (m6A) plays a key role in the occurrence and development of various cancers. Fat mass and obesity‐associated protein (FTO) was is involved in multiple cancers owing to its demethylase activity, and the molecular mechanism underlying ...
Zhuang Sun   +5 more
doaj   +1 more source

A loop matters for FTO substrate selection [PDF]

open access: yesProtein & Cell, 2010
Recent studies have unequivocally established the link between FTO and obesity. FTO was biochemically shown to belong to the AlkB-like family DNA/RNA demethylase. However, FTO differs from other AlkB members in that it has unique substrate specificity and contains an extended C-terminus with unknown functions.
Zhifu, Han   +3 more
openaire   +2 more sources

NFDI MatWerk Ontology (MWO): A BFO‐Compliant Ontology for Research Data Management in Materials Science and Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi   +4 more
wiley   +1 more source

Impacto do gene FTO na prevalência de excesso de peso: existe uma relação causal?

open access: yesRevista Brasileira de Obesidade, Nutrição e Emagrecimento, 2022
Introdução: Estudos relatam a associação entre excesso de peso e a presença de polimorfismo do gene FTO em adolescentes. Objetivo:  Desta forma, realizou-se uma revisão de literatura na tentativa de esclarecer essa relação, ainda conflitante, entre o ...
Anne Caroline Silva e Silva   +3 more
doaj  

Transparent Deformable Thin Film Electric Heater for Stable and Accurate Control of High Temperatures

open access: yesAdvanced Functional Materials, EarlyView.
Au/GaOx‐based transparent heaters combine high optical transmittance and low sheet resistance with exceptional thermal stability up to 521°C for over 6 h. The interfacial GaOx layer suppresses dewetting of Au and enhances adhesion, ensuring mechanical robustness during deformation and reliability for real‐world applications including grilling ...
Younghyun Lee   +8 more
wiley   +1 more source

Extremely Long Electron Lifetime in Spontaneously Passivated Polycrystalline Perovskite Layers via Illumination‐Assisted Trap Filling

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Perovskite solar cells (PSCs) are promising next‐generation photovoltaics. The high performance of PSCs is attributed to the long carrier lifetimes of perovskite photoabsorbers. However, the carrier lifetimes of polycrystalline perovskite layers, which serve as the photoabsorbers in practical PSCs, have remained limited to several tens of ...
Naoyuki Nishimura   +2 more
wiley   +1 more source

FTO: linking m6A demethylation to adipogenesis [PDF]

open access: yesCell Research, 2014
Polymorphism of the FTO gene encoding an N(6)-methyladenosine (m(6)A) RNA demethylase was robustly associated with human obesity; however, the mechanism by which FTO affects metabolism, considering its emerging role in RNA modification, is still poorly understood.
Moshe Shay, Ben-Haim   +2 more
openaire   +2 more sources

Water Adsorption‐Induced Color Sensor: Insight Into the Sensing Mechanism and Interfacial Engineering for Improved Responsiveness

open access: yesAdvanced Functional Materials, EarlyView.
We report a unique color‐sensing phenomenon of a TiO2/SbSI:Sb2S3 device utilizing X‐ray absorption. Based on the revealed penetration and adsorption of water onto TiO2, we successfully improved the color response speed and sensitivity by incorporating a hydrophilic polymer interlayer, thereby opening up opportunities for photodetection applications ...
Tai Kobayashi   +9 more
wiley   +1 more source

Correlated Metal LaNiO3 as a p‐Type Transparent Conductor

open access: yesAdvanced Functional Materials, EarlyView.
p‐type transparent conducting oxides are needed to enable superstrate solar cell geometries with n‐type absorbers. The p‐type correlated metal LaNiO3 combines high optical transmission with low electrical resistivity and is compatible with a range of scalable deposition processes.
Shivang Beniwal   +8 more
wiley   +1 more source

The effect of rs9930506 FTO gene polymorphism on obesity risk: a meta-analysis

open access: yesBiomolecular Concepts, 2019
Obesity is associated with polymorphisms of the fat mass and obesity associated gene (FTO). This meta-analysis aimed to investigate the association of the rs9930506 FTO gene polymorphism and obesity.
Doaei S   +11 more
doaj   +1 more source

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