Results 51 to 60 of about 114,221 (304)

m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade [PDF]

, 2019
Melanoma is one of the most deadly and therapy-resistant cancers. Here we show that N6-methyladenosine (m6A) mRNA demethylation by fat mass and obesity-associated protein (FTO) increases melanoma growth and decreases response to anti-PD-1 blockade ...
Aplin, Andrew E., Cui, Yan-Hong, Deng, Yu, He, Chuan, He, Yu-Ying, Hwang, Seungmin, Lu, Zhike, Park, Gayoung, Shah, Palak, Wei, Jiangbo, Yang, Seungwon   +10 more
core   +1 more source

FTO: linking m6A demethylation to adipogenesis [PDF]

Cell Research, 2014
Polymorphism of the FTO gene encoding an N(6)-methyladenosine (m(6)A) RNA demethylase was robustly associated with human obesity; however, the mechanism by which FTO affects metabolism, considering its emerging role in RNA modification, is still poorly understood.
Moshe Shay, Ben-Haim, Sharon, Moshitch-Moshkovitz, Gideon, Rechavi   +2 more
openaire   +2 more sources

Electroactive Metal–Organic Frameworks for Electrocatalysis

Advanced Functional Materials, EarlyView.
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska, Yutong Luo, Ruyan Zhao, Jianjun Zhang, Mingchao Wang, Xinliang Feng, Eike Brunner, Stefan Kaskel   +7 more
wiley   +1 more source

Electrochemical Investigation of High-Performance Dye-Sensitized Solar Cells Based on Molybdenum for Preparation of Counter Electrode [PDF]

, 2013
In order to improve the photocurrent conversion efficiency of dye-sensitized solar cells (DSSCs), we studied an alternative conductor for the counter electrode and focused on molybdenum (Mo) instead of conventional fluorine-doped tin oxide (FTO). Because
Jeon, Dong-Hwan, Jo, Hyo Jeong, Kang, Jin-Kyu, Kim, Dae-Hwan, Sim, Kyoseung, Sung, Shi-Joon   +5 more
core  

Fat Mass and Obesity-Associated Gene (FTO) in Eating Disorders: Evidence for Association of the rs9939609 Obesity Risk Allele with Bulimia nervosa and Anorexia nervosa [PDF]

, 2012
Objective: The common single nucleotide polymorphism (SNP) rs9939609 in the fat mass and obesity-associated gene (FTO) is associated with obesity. As genetic variants associated with weight regulation might also be implicated in the etiology of eating ...
André Scherag, Anke Hinney, Beate Herpertz-Dahlmann, Benedetta Nacmias, Brandon H. Greene, Brandys MK, Cecil JE, Cellini E, Chang YC, Christian Fleischhaker, Coners H, Daniela Di Bella, Day J, Dina C, Elena Cellini, Fairburn CG, Fernando Fernández-Aranda, Frayling TM, Gorwood P, Harald Grallert, Hebebrand J, Heinz-Erich Wichmann, Helmut Schäfer, Herder C, Herpertz-Dahlmann B, Herpertz-Dahlmann BM, Hinney A, Hinney A, Hinney A, Holtkamp K, Hotta K, Hunt SC, Johannes Hebebrand, Jonassaint CR, Kring SI, Kromeyer-Hauschild K, Labayen I, Laura Bellodi, López-Bermejo A, Manfred Fichter, Maria C. Cavallini, Marta Ribasés, Milos G, Monica Gratacòs, Müller TD, Nishimura H, Peng S, Pinheiro AP, Ribasés M, Ruiz JR, Sandro Sorbi, Scuteri A, Slager SL, Stefan Ehrlich, Stefano Erzegovesi, Susann Scherag, Thomas Illig, Timo D. Müller, Tozzi F, Ulrike Lehmkuhl, Valdo Ricca, Wardle J, Wardle J, Wichmann HE, Wigginton E, Wolfgang Herzog, Xavier Estivill   +66 more
core   +4 more sources

Homogenous FACsPbI3 Perovskite Solar Cells Enabled by a Seed‐Facilitated Cation Exchange Strategy

Advanced Functional Materials, EarlyView.
A novel seed‐facilitated cation exchange strategy is designed for homogenous FACsPbI3 perovskites using the biomass‐derived solvent γ‐valerolactone. Pre‐deposited 0D Cs4PbI6 seeds induce rapid nucleation and efficient cation exchange, producing a uniform FA–Cs distribution and significantly reducing defect density, enabling high‐performance and stable ...
Meng Ren, Guodong Chen, Haifei Wang, Bowei Li, Yuetian Chen, Jiahao Guo, Yingping Fan, Shaowei Wang, Yanfeng Miao, Feng Gao, Yixin Zhao   +10 more
wiley   +1 more source

Emerging Roles of N6-Methyladenosine Demethylases and Its Interaction with Environmental Toxicants in Digestive System Cancers

Cancer Management and Research, 2021
Caiping Liu,1 Sheng Yang,1 Yanqiu Zhang,2 Chuntao Wang,3 Dandan Du,1 Xian Wang,1 Tong Liu,1 Geyu Liang1 1School of Public Health, Key Laboratory of Environmental Medicine Engineering, Ministry of Education, Southeast University, Nanjing, 210009, Jiangsu,
Liu C, Yang S, Zhang Y, Wang C, Du D, Wang X, Liu T, Liang G   +7 more
doaj  

Investigating the influence of precursor temperature on the bandgap energy, structural, and morphological features of Ti-doped barium sulphide material for photovoltaic application [PDF]

Physics Access
In this study, we use electrochemical deposition on FTO to grow BaTiS thin films. By varying the temperature of the precursors, we conducted thorough growth studies to understand how these process parameters affected the structure of BaTiS films.
Emmanuel O Okechukwua, Imosobomeh L Ikhioya, Azubuike J Ekpunobi   +2 more
doaj   +1 more source

Exploring Pb‐Chelation Chemistry in the Crystallization Dynamics of Halide Perovskites

Advanced Functional Materials, EarlyView.
A mechanism of how Pb‐chelation chemistry governs coordination geometry and initial nucleation behavior at the precursor level of halide perovskite, by regulating the deprotonation state of a chelating additive, is elucidated. This allows for innovative reaction‐system design principles that promote coherent growth while suppressing defect formation in
Byeong Jun Kim, Inseo Cho, Jung Geon Son, Yifan Yu, Gunhee Kim, Eunseo Shin, Seyeon Eom, Minsub Um, Subeom Shin, Hyungju Ahn, Dong Suk Kim, Hochan Song, Hyosung Choi, Jonghee Yang   +13 more
wiley   +1 more source

The role of genes and myokines of developing sarcopenia: A review [PDF]

Consilium Medicum
Sarcopenia is associated with progressive generalized skeletal muscle weakness, persistent decline in muscle strength, function, and quality of life in the elderly population. The presence of sarcopenia worsens the prognosis of older patients.
Farida V. Valeeva, Zhanna A. Rodygina, Tatyana S. Yilmaz   +2 more
doaj   +1 more source