Results 61 to 70 of about 41,205 (261)

FTO alleviated the diabetic nephropathy progression by regulating the N6-methyladenosine levels of DACT1

open access: yesOpen Life Sciences
FTO-medicated m6A modification of DACT1 was dependent on IGF2BP1 in DN progression.
Li Xuanwen   +3 more
doaj   +1 more source

Impacto do gene FTO na prevalência de excesso de peso: existe uma relação causal?

open access: yesRevista Brasileira de Obesidade, Nutrição e Emagrecimento, 2022
Introdução: Estudos relatam a associação entre excesso de peso e a presença de polimorfismo do gene FTO em adolescentes. Objetivo:  Desta forma, realizou-se uma revisão de literatura na tentativa de esclarecer essa relação, ainda conflitante, entre o ...
Anne Caroline Silva e Silva   +3 more
doaj  

FTO influences adipogenesis by regulating mitotic clonal expansion [PDF]

open access: yes, 2015
The fat mass and obesity-associated (FTO) gene plays a pivotal role in regulating body weight and fat mass; however, the underlying mechanisms are poorly understood. Here we show that primary adipocytes and mouse embryonic fibroblasts (MEFs) derived from
Andrew, Daniel   +10 more
core   +1 more source

Post‐Deposition Photonic Curing Treatment for Improved Sb2Se3 Photovoltaic Performance

open access: yesAdvanced Optical Materials, EarlyView.
Millisecond‐scale photonic curing overcomes the open‐circuit voltage deficit in Sb2Se3 solar cells by transforming the rear interface. This ultrafast treatment enhances crystallographic texture and smooths the absorber surface, suppressing interfacial recombination and boosting power conversion efficiency to 8.2%.
Udari Wijesinghe   +5 more
wiley   +1 more source

Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy

open access: yesNeural Regeneration Research
Salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, Sal) is a catechol isoquinoline that causes neurotoxicity and shares structural similarity with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, an environmental toxin that causes Parkinson ...
Jianan Wang   +7 more
doaj   +1 more source

Pharmacological inhibition of FTO.

open access: yes, 2015
In 2007, a genome wide association study identified a SNP in intron one of the gene encoding human FTO that was associated with increased body mass index.
Sara Wells (106305)   +25 more
core   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

open access: yesAdvanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen   +9 more
wiley   +1 more source

FTO is ubiquitously expressed.

open access: yes, 2017
(A) Western blot analysis of the indicated mouse tissues probing for Fto using antibody from Epitomics (see Table 1). BAT; brown adipose tissue, WAT; white adipose tissue.
Pauline Isakson (3833122)   +5 more
core   +1 more source

FTO and Obesity: The Missing Link [PDF]

open access: yes, 2011
Genome-wide association studies revealed that variants within FTO (fat-mass- and obesity-associated) are strongly associated with obesity susceptibility.
Farooqi, I. Sadaf, I. Sadaf Farooqi
core   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

open access: yesAdvanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

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