Results 81 to 90 of about 26,295 (268)
Open Life SciencesFTO-medicated m6A modification of DACT1 was dependent on IGF2BP1 in DN progression.
Li Xuanwen +3 more
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Advanced Science, EarlyView.A BCP‐derived buried‐interface strategy establishes Na‐BCS as a chemically bonded molecular bridge. By combining sulfonate anchoring to SnO2 with preserved BCP–Pb2+ coordination, Na‐BCS simultaneously passivates oxide‐ and perovskite‐side defects, suppresses non‐radiative recombination, and delivers a surface recombination velocity of 8.6 cm s−1, a ...
Dong Hyun Kim +9 more
wiley +1 more source
Neural Regeneration ResearchSalsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, Sal) is a catechol isoquinoline that causes neurotoxicity and shares structural similarity with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, an environmental toxin that causes Parkinson ...
Jianan Wang +7 more
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Gene Polymorphisms of m6A Erasers FTO and ALKBH1 Associated with Susceptibility to Gastric Cancer
Pharmacogenomics and Personalized Medicine, 2022 Yue Li,* Dalei Zhou,* Qing Liu, Weijie Zhu, Zulu Ye, Caiyun He Department of Molecular Diagnostics, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine ...
Li Y, Zhou D, Liu Q, Zhu W, Ye Z, He C
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PLoS ONE, 2010 Sequence variants in the first intron of FTO are strongly associated with human obesity and human carriers of the risk alleles show evidence for increased appetite and food intake. Mice globally lacking Fto display a complex phenotype characterised by both increased energy expenditure and increased food intake.
Tung, Yi-Chun Loraine +6 more
openaire +6 more sources
Advanced Science, EarlyView.Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du +9 more
wiley +1 more source
Pharmacogenomics and Personalized Medicine, 2021 Feng Xiao, Jianrong Zhou School of Nursing, Chongqing Medical University, Chongqing, 400016, People’s Republic of ChinaCorrespondence: Jianrong ZhouSchool of Nursing, Chongqing Medical University, No. 1 Changda Road, Jiulongpo District, Chongqing, 400016,
Xiao F, Zhou J
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Advanced Science, EarlyView.Surface‐charged N‐CQDs serve as both electrolyte additives and photocathode modifiers. Electrodeposited N‐CQDs on Cu2O form a stable composite, steering 4e− ORR toward water. A quasi‐solid electrolyte with N‐CQDs aids charge migration, electrode‐electrolyte interfacial compatibility and replenishes active sites.
Yang Wu +12 more
wiley +1 more source
Adipocyte, 2019 This study is the first to identify the effects of FTO genotype on the interactions between the level of macro-nutrients intake and the expression level of fat mass and obesity associated (FTO) and homeobox transcription factor iriquois-3 (IRX3) genes ...
Saeid Doaei +9 more
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Advanced Science, EarlyView.This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei +18 more
wiley +1 more source