Results 91 to 100 of about 26,295 (268)

GENETIC ASPECTS OF ADULT OBESITY FORMATION

Медицина в Кузбассе, 2023
Obesity is a multifactorial disease, and the genetic component occupies an important place in its pathogenesis. One of the most studied and closely associated with monogenic obesity is the FTO (fat mass and obesity associated) gene.
Варвара Ивановна Минина, Анастасия Александровна Яковлева, Анастасия Валерьевна Понасенко, Ольга Александровна Соболева, Анастасия Владимировна Торгунакова, Елена Александровна Киселева, Лидия Александровна Варич, Татьяна Андреевна Толочко, Анна Дмитриевна Веснина, Игорь Анатольевич Те, Яна Александровна Захарова   +10 more
doaj  

Advancing the Design of High‐Efficiency Printable Hole‐Conductor‐Free Mesoscopic Perovskite Solar Cells Through Machine Learning

Advanced Science, EarlyView.
Based on the largest printable mesoscopic perovskite solar cells database we established, stacking model achieved precise PCE prediction (R2 = 0.73, MAE = 2.18%). Multiple experiments verified the accuracy of the model, which guided the fabrication of high‐PCE devices with an efficiency of 19.36%.
Hao Meng, Jingzi Zhang, Xu Zhu, Yuelin Wang, Antai Yang, Kailong Hu, Chengquan Zhong, Jiakai Liu, Menghan Dun, Xi Lin   +9 more
wiley   +1 more source

Active Fraction of Polyrhachis Vicina Roger (AFPR) Ameliorate Depression Induced Inflammation Response by FTO/miR-221-3p/SOCS1 Axis

Journal of Inflammation Research, 2023
Junhui He,1,* Jiaxiu Xie,1,* Guili Zhou,2,* Chunlian Jia,2 Dongbo Han,2 Dongmei Li,1 Jie Wei,1 Yi Li,1 Renshan Huang,1 Chunlian Li,1 Bo Wang,3 Chao Wei,3 Qibiao Su,4 Kedao Lai,1 Guining Wei1 1Department of Pharmacology, Key Laboratory of ...
He J, Xie J, Zhou G, Jia C, Han D, Li D, Wei J, Li Y, Huang R, Li C, Wang B, Wei C, Su Q, Lai K, Wei G   +14 more
doaj  

FTO Table S6

, 2019
Supplemental Table S6 for manuscript "Functional Genomic Characterization of the Fat Mass and Obesity-Associated (FTO) Locus in African Americans"
openaire   +1 more source

Molecularly Engineered Wing‐Shaped Azobenzene Memristors for Logic‐in‐Memory and Edge Visual Intelligence

Advanced Science, EarlyView.
Rational engineering of terminal substituents in symmetric azobenzene‐based molecules enables precise control over conformationally coupled charge‐transfer processes. This design yields tunable nonvolatile resistive memory behaviors, ranging from write‐once‐read‐many‐times (WORM) to rewritable switching.
Yanze Liu, Tao Han, Jiahui Ding, Hong Lian, Lingling Yao, Zhaoxin Xu, Xingyu Zhang, Shuanglong Wang, Jiangnan Xia, Tianchi Zhang, Weiwei Kang, Qingchen Dong   +11 more
wiley   +1 more source

High‐Performance Transparent Solid Polymer Electrolyte Based on Copolymer of Deep Eutectic Electrolyte and Methyl Methacrylate for Electrochemical Devices

Advanced Science, EarlyView.
A copolymerization strategy using a polymerizable deep eutectic electrolyte with MMA forms efficient ion‐transport pathways while maintaining excellent transparency. The solid polymer electrolyte simultaneously achieves 17.8 MPa mechanical strength and 1.43 mS cm−1 ionic conductivity, enhancing long‐term cycling stability in Li|LFP batteries and ...
Tingting Chen, Sijia Han, Likun Wang, Sainan Ma, Liping Zhang, Yong Liu, Gaorong Han   +6 more
wiley   +1 more source

Pan-Cancer Analysis of the N6-Methyladenosine Eraser FTO as a Potential Prognostic and Immunological Biomarker

International Journal of General Medicine, 2021
Chengwen Zhao,1,* Yonghui Liu,1,* Shaoqing Ju,1,2 Xudong Wang1,2 1Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People’s Republic of China; 2Department of Public Health, Nantong University ...
Zhao C, Liu Y, Ju S, Wang X
doaj  

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

No Association Between FTO Gene Polymorphisms and Central Nervous System Tumor Susceptibility in Chinese Children

Pharmacogenomics and Personalized Medicine, 2021
Yuxiang Liao,1 Li Yuan,2 Zhiping Zhang,1 Ao Lin,3 Jingying Zhou,4 Zhenjian Zhuo,3 Jie Zhao1 1Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, Changsha, People’s Republic of China; 2Department of Pathology ...
Liao Y, Yuan L, Zhang Z, Lin A, Zhou J, Zhuo Z, Zhao J   +6 more
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Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source