Emerging Role and Mechanism of the FTO Gene in Cardiovascular Diseases. [PDF]
Biomolecules, 2023 The fat mass and obesity-associated (FTO) gene was the first obesity-susceptibility gene identified through a genome-wide association study (GWAS). A growing number of studies have suggested that genetic variants of FTO are strongly associated with the risk of cardiovascular diseases, including hypertension and acute coronary syndrome. In addition, FTO
Xu ZY, Jing X, Xiong XD.
europepmc +4 more sources
Association of FTO gene variants rs9939609 and rs1421085 with polycystic ovary syndrome
Egyptian Journal of Medical Human Genetics, 2022 Background Polycystic ovary syndrome (PCOS) is among the most common complex genetic endocrinopathy, and its etiology and pathophysiology remain controversial.
Alaa A. Alnafjan +4 more
doaj +2 more sources
FTO gene variants and consumption of alcoholic beverages [PDF]
Alcoholism and Drug Addiction, 2021 The aim of this review is to present the role of FTO gene sequence variation in determining predisposition to specific forms of alcohol consumption. This systematic review includes studies published in 2011-2013 and 2019 from the PubMed, Science Direct ...
Anna Karolina Flaga +2 more
doaj +3 more sources
Role of rs9939506 polymorphism of FTO gene in resistance to eating in male adolescents [PDF]
BMC Pediatrics, 2023 Background Single Nucleotide Polymorphisms (SNPs) of the Fat mass and obesity-associated (FTO) gene may be associated with obesity by regulating appetite.
Ali Shaker +14 more
doaj +2 more sources
Indian Heart Journal, 2017 The various studies have examined the relationship between FTO gene expression and macronutrients levels. In order to obtain better viewpoint from this interactions, all of existing studies were reviewed systematically.
Saeid Doaei +4 more
doaj +3 more sources
FTO gene expression in diet-induced obesity is downregulated by Solanum fruit supplementation [PDF]
Open Life Sciences, 2022 The Fat Mass and Obesity-associated (FTO) gene has been shown to play an important role in developing obesity, manifesting in traits such as increased body mass index, increased waist-to-hip ratio, and the distribution of adipose tissues, which increases
Asuquo Edeke Affiong +5 more
doaj +2 more sources
The effects of FTO gene rs9939609 polymorphism on the association between colorectal cancer and dietary intake [PDF]
Frontiers in Nutrition, 2023 Maryam Gholamalizadeh +2 more
exaly +2 more sources
Identification and Association of Single Nucleotide Polymorphisms of the FTO Gene with Indicators of Overweight and Obesity in a Young Mexican Population [PDF]
Genes, 2023 Jorge Luis Chávez-Servín +2 more
exaly +2 more sources
Association of the FTO Gene With BMI [PDF]
Obesity, 2008 Variants in the FTO gene have been strongly associated with obesity in a very large sample (38,759) of diabetic and control subjects. To replicate these findings, the previously reported SNP in the FTO gene (rs9939609, T/A) was genotyped in 5,607 subjects from five different Utah studies.
Steven C, Hunt +7 more
openaire +2 more sources
The FTO gene and measured food intake in children [PDF]
International Journal of Obesity, 2008 Polymorphisms in the obesity-associated gene, FTO, have been linked with sensitivity to satiety in children, indicating FTO may be influencing one of the regulatory drivers underlying food intake. In this study, we tested the hypothesis that food intake in a standard eating behaviour paradigm in which palatable food is offered under conditions of ...
Wardle, J. +3 more
openaire +3 more sources