Results 61 to 70 of about 7,322,114 (249)
Extinction of tyrosine aminotransferase gene activity in somatic cell hybrids involves modification and loss of several essential transcription factors [PDF]
, 1993 Extinction is defined as the loss of cell type-specific gene expression that occurs in somatic cell hybrids derived by fusion of cells with dissimilar phenotypes.
Boshart, Michael +2 more
core +1 more source
Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study. [PDF]
, 2017 We evaluated the associations between single nucleotide polymorphisms and different clinical parameters related to type 2 diabetes mellitus (T2DM), obesity risk, and metabolic syndrome (MS) in a Kazakh cohort. A total of 1336 subjects, including 408 T2DM
Eap, C.B. +5 more
core +2 more sources
Advanced Materials Technologies, EarlyView.ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source
FTO associations with obesity and telomere length
Journal of Biomedical Science, 2017 This review examines the biology of the Fat mass- and obesity-associated gene (FTO), and the implications of genetic association of FTO SNPs with obesity and genetic aging.
Yuling Zhou +2 more
doaj +1 more source
A High Intake of Saturated Fatty Acids Strengthens the Association between the Fat Mass and Obesity-Associated Gene and BMI123 [PDF]
, 2011 Evidence that physical activity (PA) modulates the association between the fat mass and obesity-associated gene (FTO) and BMI is emerging; however, information about dietary factors modulating this association is scarce.
Ahmad +51 more
core +1 more source
Fat Mass and Obesity Associated (FTO) Gene and Hepatic Glucose and Lipid Metabolism
Nutrients, 2018 Common genetic variants of the fat mass and obesity associated (FTO) gene are strongly associated with obesity and type 2 diabetes. FTO is ubiquitously expressed.
T. Mizuno
semanticscholar +1 more source
Scientific Reports, 2020 Sarcopenia is characterized by low skeletal muscle, a complex trait with high heritability. With the dramatically increasing prevalence of obesity, obesity and sarcopenia occur simultaneously, a condition known as sarcopenic obesity. Fat mass and obesity-
S. Ran +14 more
semanticscholar +1 more source
Advanced Science, EarlyView.TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang +12 more
wiley +1 more source
Association of FTO gene with obesity in Polish schoolchildren [PDF]
Anthropological Review, 2014 The goal of the study was verification of fat mass and obesity-associated (FTO) gene polymorphisms as significant risk factors of obesity in the population of Polish children. Body mass index (BMI) and DNA were evaluated, where DNA was extracted from saliva, collected from 213 children at the age of 6–13 years. DNA was genotyped by PCR ...
Sitek, A. +5 more
openaire +3 more sources
Fat tissue accretion in children and adolescents : interplay between food responsiveness, gender, and the home availability of snacks [PDF]
, 2017 The appetitive trait "food responsiveness" is assumed to be a risk factor for adiposity gain primarily in obesogenic environments. So far, the reported results are inconsistent in school-aged children, possibly because these studies did not take into ...
Braet, Caroline +5 more
core +1 more source