Results 11 to 20 of about 4,732 (207)

Association of FTO rs9939609 polymorphism with serum leptin, insulin, adiponectin, and lipid profile in overweight adults

Adipocyte, 2020
FTO gene polymorphisms are associated with obesity and food intake. This study aimed to investigate the association of FTO rs9939609 polymorphism genotypes with serum glucose, lipid profile and serum hormones level. This cross-sectional study was carried
Saeid Doaei, Maryam Gholamalizadeh, Majid Fardaei   +2 more
exaly   +2 more sources

Polymorphisms in the FTO Gene and Their Association With Cancer Risk: A Comprehensive Review and Meta-Analysis. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background This meta‐analysis aimed to clarify the connection between six polymorphisms in the FTO gene and susceptibility to cancer. Methods The relevant literature on the relationship between FTO variants and cancer susceptibility was comprehensively gathered from PubMed, Scopus, Embase, Medline, and Web of Science prior to May 20, 2024 ...
Guo F, Gao Y, Wang H, Zhou P, Zhang Y, Teng Z, Wang Y, Han Z.   +7 more
europepmc   +2 more sources

Association Between Industrialized Dietary Pattern and Cardiometabolic Risk Factors in Children With FTO RS9939609 Gene Polymorphism. [PDF]

Mol Nutr Food Res
This study examined how dietary patterns affect health in children aged 4–7 years, especially in the presence of the fat mass and obesity associated (FTO) gene polymorphism. Researchers found that children with FTO gene polymorphism who ate more industrialized foods had higher risks of health problems and cardiometabolic risk with higher values of the ...
Kiepper BHDLP, Azevedo FM, Candido AC, Silva MA, de Novaes JF, Resende CMM, Durso DF, Alvarez-Leite JI, Velasquez-Melendez G, Franceschini SDCC, de Souza ECG, Ribeiro SAV.   +11 more
europepmc   +2 more sources

Precision nutrition in weight loss and neuroendocrine control of people with obesity: The study protocol of a factorial randomised controlled trial (GenON Programme). [PDF]

Diabetes Obes Metab
Abstract Aims Precision nutrition, guided by genetic testing, has emerged as a promising approach for managing obesity. However, robust clinical trials testing its effectiveness in real‐world dietary interventions remain scarce. The GenOn Programme aims to evaluate whether tailoring nutritional care based on genetic risk for obesity enhances weight ...
Balbino KP, Kravchychyn ACP, Cândido FG, Dias MME, Mendes TAO, Oliveira LL, Castro LCV, Bressan J, de la Garza AL, Milagro FI, Zulet MA, Hermsdorff HHM.   +11 more
europepmc   +2 more sources

The association between FTO rs9939609 polymorphism and serum lipid profile in adult women [PDF]

Diabetology & Metabolic Syndrome, 2021
Background FTO gene is considered to play an important role in many metabolic diseases. Evidence from studies indicated the possible association between the FTO rs9939609 polymorphisms with serum lipid profile.
Vahideh Jalili, Zohreh Mokhtari, Samira Rastgoo, Azadeh Hajipour, Fatemeh Bourbour, Maryam Gholamalizadeh, Alireza Mosavi Jarrahi, Sepehr JavadiKooshesh, Alireza Moslem, Morteza Abdollahi, Saeid Doaei   +10 more
doaj   +3 more sources

Effect of FTO rs9939609 variant on insulin resistance in obese female adolescents [PDF]

BMC Research Notes, 2018
Objectives FTO rs9939609 variant has been shown to be associated with insulin resistance in Caucasian children. However, studies in Asia show inconsistent findings.
Kristy Iskandar, Suryono Yudha Patria, Emy Huriyati, Harry Freitag Luglio, Madarina Julia, Rina Susilowati   +5 more
doaj   +3 more sources

Association of FTO common variant (rs9939609) with body fat in Turkish individuals [PDF]

Lipids in Health and Disease, 2019
Background Variations in the fat mass and obesity-associated (FTO) gene (16q12.2) are associated with obesity in some populations. This study aimed to determine the relationship between FTO gene polymorphism and adiposity&related markers in Turkish ...
Duygu AĞAGÜNDÜZ, Makbule GEZMEN-KARADAĞ   +1 more
doaj   +4 more sources

Obesity in the Balinese is associated with FTO rs9939609 and rs1421085 single nucleotide polymorphisms [PDF]

PeerJ, 2020
Obesity prevalence is increasing worldwide, including in the Bali Province, Indonesia, a popular tourism destination area. The common single nucleotide polymorphisms (SNPs) rs9939609 and rs1421085 of the fat mass and obesity-associated (FTO) gene have ...
Lidwina Priliani, Sukma Oktavianthi, Ria Hasnita, Hazrina T. Nussa, Rut C. Inggriani, Clarissa A. Febinia, Anom Bowolaksono, Rini Puspitaningrum, Rully A. Nugroho, Ketut Suastika, Safarina G. Malik   +10 more
doaj   +4 more sources

Fat Mass and Obesity-Related (FTO) Gene Variant Is a Predictor of CVD in T2DM Patients [PDF]

Journal of Diabetes Research
Conclusion: The FTO gene variant rs9939609 has a strong association with T2DM and CVD. The AA genotype of FTO gene variants rs9939609 showed a strong association with most of the risk factors of CVD and T2DM.
Mazhar Hussain, Akbar Waheed, Asim Elahi, Ghulam Mustafa   +3 more
doaj   +2 more sources

An obesogenic FTO allele causes accelerated development, growth and insulin resistance in human skeletal muscle cells [PDF]

Nature Communications
Human GWAS have shown that obesogenic FTO polymorphisms correlate with lean mass, but the mechanisms have remained unclear. It is counterintuitive because lean mass is inversely correlated with obesity and metabolic diseases. Here, we use CRISPR to knock-
Lu Guang, Shilin Ma, Ziyue Yao, Dan Song, Yu Chen, Shuqing Liu, Peng Wang, Jiali Su, Yuefan Wang, Lanfang Luo, Ng Shyh-Chang   +10 more
doaj   +2 more sources