Results 11 to 20 of about 2,096 (161)

Obesity in the Balinese is associated with FTO rs9939609 and rs1421085 single nucleotide polymorphisms [PDF]

PeerJ, 2020
Obesity prevalence is increasing worldwide, including in the Bali Province, Indonesia, a popular tourism destination area. The common single nucleotide polymorphisms (SNPs) rs9939609 and rs1421085 of the fat mass and obesity-associated (FTO) gene have ...
Lidwina Priliani, Sukma Oktavianthi, Ria Hasnita, Hazrina T. Nussa, Rut C. Inggriani, Clarissa A. Febinia, Anom Bowolaksono, Rini Puspitaningrum, Rully A. Nugroho, Ketut Suastika, Safarina G. Malik   +10 more
doaj   +5 more sources

The Link Between Spontaneous Abortion and Vitamin E may be Influenced by the Fat Mass and Obesity-Associated Gene, a Case-Control Study. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Spontaneous abortion (SA) may be affected by several variables including genetics and lifestyle factors. A recent study discovered that variations in the FTO gene have been associated to both SA and dietary intake. The objective of the study is to examine the association between vitamin E and abortion in individuals with ...
Saeedirad Z, Mousavi Mele M, Shamsi-Goushki A, Khodarahmi S, Mirshafaei MA, Tahavorgar A, Nami S, Namakian Yazdi SA, Lahiji NP, Mobarakeh KA, Khoshdooz S, Doaei S, Ajami M, Gholamalizadeh M.   +13 more
europepmc   +2 more sources

Effect of FTO rs9939609 variant on insulin resistance in obese female adolescents [PDF]

BMC Research Notes, 2018
Objectives FTO rs9939609 variant has been shown to be associated with insulin resistance in Caucasian children. However, studies in Asia show inconsistent findings.
Kristy Iskandar, Suryono Yudha Patria, Emy Huriyati, Harry Freitag Luglio, Madarina Julia, Rina Susilowati   +5 more
doaj   +3 more sources

Coevolution of Human Diet and Gut Microbiome: Implications for Nutrigenomics and Cross-Population Health. [PDF]

Int J Microbiol
The coevolution of the human diet and gut microbiome has played a pivotal role in shaping metabolic, immune, and epigenetic functions across human history. Dietary transitions from high‐fiber ancestral patterns to modern ultraprocessed diets have markedly influenced microbial diversity and functionality, contributing to the emergence of chronic ...
Sandra F, Scania AE, Dewi NM, Ranggaini D, Halim J, Pakpahan A, Lee KH.   +6 more
europepmc   +2 more sources

Genetics of Common Obesity in Children and Adolescents. [PDF]

Ann N Y Acad Sci
Abstract Childhood obesity is a multifactorial public health problem worldwide. Genetic variation influences the predisposition to develop obesity at early stages of life. Childhood obesity may be classified as syndromic, monogenic, or polygenic depending on the genetic component.
León-Reyes G, Alavez FJL, Tejero ME.
europepmc   +2 more sources

Association of FTO common variant (rs9939609) with body fat in Turkish individuals [PDF]

Lipids in Health and Disease, 2019
Background Variations in the fat mass and obesity-associated (FTO) gene (16q12.2) are associated with obesity in some populations. This study aimed to determine the relationship between FTO gene polymorphism and adiposity&related markers in Turkish ...
Duygu AĞAGÜNDÜZ, Makbule GEZMEN-KARADAĞ   +1 more
doaj   +4 more sources

The association between FTO rs9939609 polymorphism and serum lipid profile in adult women [PDF]

Diabetology & Metabolic Syndrome, 2021
Background FTO gene is considered to play an important role in many metabolic diseases. Evidence from studies indicated the possible association between the FTO rs9939609 polymorphisms with serum lipid profile.
Vahideh Jalili, Zohreh Mokhtari, Samira Rastgoo, Azadeh Hajipour, Fatemeh Bourbour, Maryam Gholamalizadeh, Alireza Mosavi Jarrahi, Sepehr JavadiKooshesh, Alireza Moslem, Morteza Abdollahi, Saeid Doaei   +10 more
doaj   +3 more sources

Polymorphisms in the FTO Gene and Their Association With Cancer Risk: A Comprehensive Review and Meta-Analysis. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background This meta‐analysis aimed to clarify the connection between six polymorphisms in the FTO gene and susceptibility to cancer. Methods The relevant literature on the relationship between FTO variants and cancer susceptibility was comprehensively gathered from PubMed, Scopus, Embase, Medline, and Web of Science prior to May 20, 2024 ...
Guo F, Gao Y, Wang H, Zhou P, Zhang Y, Teng Z, Wang Y, Han Z.   +7 more
europepmc   +2 more sources

An obesogenic FTO allele causes accelerated development, growth and insulin resistance in human skeletal muscle cells [PDF]

Nature Communications
Human GWAS have shown that obesogenic FTO polymorphisms correlate with lean mass, but the mechanisms have remained unclear. It is counterintuitive because lean mass is inversely correlated with obesity and metabolic diseases. Here, we use CRISPR to knock-
Lu Guang, Shilin Ma, Ziyue Yao, Dan Song, Yu Chen, Shuqing Liu, Peng Wang, Jiali Su, Yuefan Wang, Lanfang Luo, Ng Shyh-Chang   +10 more
doaj   +2 more sources

Hubungan antara polimorfisme gen Fat Mass Obesity Associated (FTO) rs9939609 dengan persentase lemak tubuh pada dewasa muda dengan obesitas sentral

JKS (Jurnal Kedokteran Syiah Kuala), 2023
Penelitian ini bertujuan untuk menganalisis hubungan polimorfisme gen FTO rs9939609 dengan persentase lemak tubuh pada dewasa muda dengan obesitas sentral pada mahasiswa kedokteran UNRI.
Nurhasanah Nurhasanah, Ulfah Ulfah
doaj   +1 more source