Results 51 to 60 of about 4,732 (207)

Variant rs9939609 in the gene is associated with body mass index among Chinese children [PDF]

, 2010
Background Fat-mass and obesity-associated (FTO) gene is a gene located in chromosome region 16q12.2. Genetic variants in FTO are associated with the obesity phenotype in European and Hispanic populations.
Hongyun Fang, Yanping Li, Songming Du, Xiaoqi Hu, Qian Zhang, Ailing Liu, Guansheng Ma   +6 more
core   +2 more sources

Gene sequence variants PPARGC1Ars8192678, PPARG2rs1801282, FTORS9939609, LEPRS7799039 and LEPRRS1137101 in non-alcoholic fatty liver disease [PDF]

Saratov Medical Journal, 2023
Objective: assessing the association of sequence variants rs8192678, rs1801282, rs9939609, rs7799039 and rs1137101in PPARGC1A, PPARG2, FTO, LEP and LEPR genes, respectively,with non-alcoholic fatty liver disease (NAFLD) inyounger adults (18-44 years ...
Pankova, Ekaterina D. , Chulkov, Vasiliy S. , Gavrilova, Elena S. , Zotova, Maria A. , Sumerkina, Veronika A. , Zhmaylova, Svetlana V. , Okonenko, Tatiana I.   +6 more
doaj   +1 more source

The FTO genotype as a useful predictor of body weight maintenance: Initial data from a 5-year follow-up study [PDF]

, 2014
ObjectiveWe examined associations between the fat-mass and obesity-associated (FTO) gene (rs9939609) and any weight change over a 5-year period following a 14-week lifestyle intervention among middle-aged Japanese women.Materials/MethodsOne hundred ...
Hotta Kikuko, Matsuo Tomoaki, Nakata Yoshio, Tanaka Kiyoji, 中田 由夫, 田中 喜代次   +5 more
core   +1 more source

Association between FTO variant and change in body weight and its interaction with dietary factors: the DiOGenes study [PDF]

, 2012
Although FTO is an established obesity-susceptibility locus, it remains unknown whether it influences weight change in adult life and whether diet attenuates this association.
Boeing, Heiner, Bouatia-Naji, Nabila, Feskens, Edith J M, Hansen, Rikke D, Holst, Claus, Jakobsen, Marianne U, Loos, Ruth J F, Masala, Giovanna, Meidtner, Karina, Overvad, Kim, Palli, Domenico, Saris, Wim H M, Sørensen, Thorkild I A, Tjønneland, Anne, van der A, Daphne L, Vimaleswaran, Karani Santhanakrishnan, Wareham, Nicholas J, Ängquist, Lars   +17 more
core   +2 more sources

The obesity associated FTO gene polymorphism and the risk of preeclampsia in Iranian women: A case–control study

Hypertension in Pregnancy, 2023
Background Preeclampsia (PE) is one of the leading disorders in pregnant women with maternal and fetal complications. Obesity is considered an important risk factor for the development of PE.
Ghasem Azizi-Tabesh, Hossein Sadeghi, Arezoo Farhadi, Mohammad Foad Heidari, Aghdas Safari, Mehdi Shakouri Khomartash, Javad Behroozi, Saeid Doaei, Maryam Gholamalizadeh   +8 more
doaj   +1 more source

Common Variant rs9939609 in Gene FTO Confers Risk to Polycystic Ovary Syndrome

PLoS ONE, 2013
Fat mass and obesity-associated gene (FTO) has been associated with obesity, especially the common variant rs9939609. Polycystic ovary syndrome (PCOS) is a complex endocrine-metabolic disorder and over 50% of patients are overweight/obese. Thus FTO is a potential candidate gene for PCOS but their relationship is confusing and remains to be clarified in
Tao Li, Keliang Wu, Li You, Xiuye Xing, Peng Wang, Linlin Cui, Hongbin Liu, Yuqian Cui, Yuehong Bian, Yunna Ning, Han Zhao, Rong Tang, Zi-Jiang Chen   +12 more
openaire   +4 more sources

In depth analysis of the association of FTO SNP (rs9939609) with the expression of classical phenotype of PCOS: a Sri Lankan study

BMC Medical Genetics, 2020
Background PCOS is a common disorder of women due to genetic, endocrine and environmental effects that manifests from puberty. The rs9939609 variant of fat mass and obesity associated (FTO) gene is linked to metabolic derangement in PCOS.
Umayal Branavan, Sulochana Wijesundera, Vishvanath Chandrasekaran, Carukshi Arambepola, Chandrika Wijeyaratne   +4 more
doaj   +1 more source

The age of developing diabetes and FTO polymorphisms (rs9939609, rs1421085, and rs9930506)

Endokrynologia Polska, 2017
Type 2 diabetes (T2DM) is a common complex metabolic disorder that has a strong genetic predisposition. Fat mass and obesity-associated protein (FTO) is one of the genes of interest to us. Hypomethylation of a CpG site in the FTO gene was significantly associated with the risk of T2DM.
Władysław, Grzeszczak, Maciej, Molsa, Marek, Tłuczykont, Anna, Markowicz, Ryszard, Swoboda, Marta, Biedak, Anna, Kałuża, Sebastian, Sirek, Krzysztof, Strojek   +8 more
openaire   +4 more sources

FTO gene polymorphisms and obesity risk: a meta-analysis [PDF]

, 2011
Background The pathogenesis of obesity is reportedly related to variations in the fat mass and an obesity-associated gene (FTO); however, as the number of reports increases, particularly with respect to varying ethnicities, there is a need to determine ...
Sihua Peng, Yimin Zhu, Fangying Xu, Xiaobin Ren, Xiaobo Li, Maode Lai   +5 more
core   +2 more sources

Polimorfisme Gen FTO Rs9939609 Terhadap Konsentrasi Trigliserida Pada Subyek Obesitas Sentral

Jurnal Analis Kesehatan, 2023
Obesitas sentral merupakan keadaan bagian perut bagian tengah terdapat lemak yang berlebih. Penumpukan lemak berlebihan mengakibatkan peningkatan jumlah asam lemak bebas yang dihidrolisis LPL endotel. Free Fatty Acid (FFA) dilepaskan karena adanya penimbunan lemak yang berlebihan juga menghambat lipogenesis sehingga menghambat klirens serum ...
Tati Nurmaliana, Vector Stephen Dewangga
openaire   +1 more source