Results 71 to 80 of about 4,732 (207)

Nutrigenomics of the Mediterranean Diet: Gene–Diet Interactions and Bioactive Compounds in Cardiovascular Health

Food Frontiers, Volume 7, Issue 2, March 2026.
The Mediterranean diet interacts with genetic and epigenetic backgrounds to modulate nutrigenomic mechanisms, including DNA methylation, histone modification and microRNA regulation. These molecular effects reduce inflammation and oxidative stress, enhance nitric oxide bioavailability and lipid metabolism and translate into improved cardiometabolic ...
Karina Ramírez‐Alarcón, Ana María Labraña, Fernanda Carrasco‐Marín, Pilar Benítez‐Cid, Rafael Zapata‐Lamana, Xavier Capó, Margalida Monserrat‐Mesquida, Antoni Sureda, Héctor Contreras, Francisca Valenzuela‐Mella, Daniel Pacheco Bravo, Daniela Calina, Maria de la Luz Cádiz‐Gurrea, Antonio Segura‐Carretero, William N. Setzer, Javad Sharifi‐Rad, Miquel Martorell   +16 more
wiley   +1 more source

Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study. [PDF]

, 2017
We evaluated the associations between single nucleotide polymorphisms and different clinical parameters related to type 2 diabetes mellitus (T2DM), obesity risk, and metabolic syndrome (MS) in a Kazakh cohort. A total of 1336 subjects, including 408 T2DM
Eap, C.B., Iskakova, A., Ramanculov, E., Saigi-Morgui, N., Sikhayeva, N., Zholdybaeva, E.   +5 more
core   +2 more sources

An Obesity-Related FTO Variant and the Risk of Preeclampsia in a Finnish Study Population

Journal of Pregnancy, 2011
Previous studies have demonstrated a common variant of the obesity and fat mass-related FTO gene, rs9939609, to be associated with obesity, type 2 diabetes, and elevated blood pressure. We investigated whether the FTO SNP rs9939609 is associated with the
Miira Klemetti, Leena M. Hiltunen, Sanna Heino, Seppo Heinonen, Eero Kajantie, Hannele Laivuori   +5 more
doaj   +1 more source

The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
N6‐methyladenosine RNA methylation regulators are intricately linked with the development of polycystic ovary syndrome (PCOS) and may influence immune cell infiltration in affected individuals. This study enhances our understanding of the molecular interactions in PCOS and suggests potential biomarkers for diagnosis and targets for therapeutic ...
Wenting Xu, Lingli Shi, Aifang Lu, Lijuan Cui, Haiqing Qian, Jiahui Wang, Mengyu Tang, Lili Zhu, Lihong Wang   +8 more
wiley   +1 more source

Association Study of rs1421085 and rs9939609 in FTO Gene with Gestational Diabetes in the Arak City [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk
Introduction: Gestational diabetes is defined as hyperglycemia with onset or first diagnosis during pregnancy, with a lower frequency than general diabetes.
Parnian Hekmatpou, Maryam Maryam Ghanbari, Milad Gholami   +2 more
doaj  

Association of rs9939609 FTO Gene Polymorphism as a Risk Factor of Obesity in Adults

GHMJ (Global Health Management Journal)
Background: The cause of obesity is an imbalance between the number of calories taken and the amount burned. Obesity is a complex disease. The FTO rs9939609 gene polymorphism is one of the genetic factors that contribute to obesity in addition to ...
Tiar Masykuroh Pratamawati, Angel Angriani Elma Budai Sadji, Gara Samara Brajadenta, Donny Nauphar   +3 more
doaj   +1 more source

Crosstalk between FTO gene polymorphism (rs9939609) and obesity‐related traits among Bangladeshi population

Health Science Reports, 2023
AbstractBackground and AimsObesity is a growing public health concern in Bangladesh, which is influenced by a complex interplay of genetic and environmental factors. The genetic variant rs9939609 of the FTO (fat mass and obesity‐associated) gene has been found to be associated with an increased risk for obesity, depending on the population studied. The
Lincon Chandra Shill, Mohammad Rahanur Alam   +1 more
openaire   +3 more sources

FTO gene polymorphisms rs9939609 and the risk of obesity among adults in Western and Asian countries: A systematic review and meta-analysis

Clinical Epidemiology and Global Health
Background: The FTO gene polymorphisms rs9939609 have been linked to obesity. It’s essential to note that genetic variations exist between different populations.
Ricvan Dana Nindrea, Phonchai Thongwichian   +1 more
doaj   +1 more source

Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In‐Depth Review

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The main objective of this review is to explore the impact of variation within the microbiome and among genes on nutrient metabolism and argue in favor of successful evidence of individualized dietary intervention for cardiovascular disease, diabetes, and obesity.
Muhammad Tayyab Arshad, M. K. M. Ali, Farhang Hameed Awlqadr, Sammra Maqsood, Ali Ikram, Md. Sakhawot Hossain, Muhammed Adem Abdullahi, M. M. Rashed   +7 more
wiley   +1 more source

Common variants of FTO are associated with childhood obesity in a cross-sectional study of 3,126 urban Indian children. [PDF]

PLoS ONE, 2012
FTO variants are robustly associated with obesity and related traits in many population and shown to have variable impact during life course. Although studies have shown association of FTO variants with adiposity in adult Indian, its association in ...
Om Prakash Dwivedi, Rubina Tabassum, Ganesh Chauhan, Saurabh Ghosh, Raman K Marwaha, Nikhil Tandon, Dwaipayan Bharadwaj   +6 more
doaj   +1 more source