Results 71 to 80 of about 3,330 (137)

Fat phenotype, associated factors and rs9939609 polymorphism of the FTO gene

Revista Brasileira de Cineantropometria e Desempenho Humano, 2010
The purpose of this work was to review the main results of studies that have analysed the relationship between the rs9939609 single nucleotide polymorphism (SNP) of the FTO gene and the manifestation of overweight/obesity with its associated co-morbidity,
William Alves Lima, Maria Fátima Glaner, Aline Pic Taylor   +2 more
doaj  

An obesogenic FTO allele causes accelerated development, growth and insulin resistance in human skeletal muscle cells

Nature Communications
Human GWAS have shown that obesogenic FTO polymorphisms correlate with lean mass, but the mechanisms have remained unclear. It is counterintuitive because lean mass is inversely correlated with obesity and metabolic diseases. Here, we use CRISPR to knock-
Lu Guang, Shilin Ma, Ziyue Yao, Dan Song, Yu Chen, Shuqing Liu, Peng Wang, Jiali Su, Yuefan Wang, Lanfang Luo, Ng Shyh-Chang   +10 more
doaj   +1 more source

Exploration of associations between the FTO rs9939609 genotype, fasting and postprandial appetite-related hormones and perceived appetite in healthy men and women

, 2019
Background: The fat mass and obesity-associated gene (FTO) rs9939609 A-allele has been associated with obesity risk. Although the exact mechanisms involved remain unknown, the FTO rs9939609 A-allele has been associated with an impaired postprandial ...
David Stensel (1257075), Monika Dowejko (7240490), Fernanda R. Goltz (7238930), Sarabjit Mastana (1249860), Greg Atkinson (718370), Alice Thackray (1251621), James King (1252200), Veronica Varela-Mato (7237928), James L. Dorling (7240829), Julie Thompson (6205940)   +9 more
core   +3 more sources

Полиморфизм гена FTO rs9939609 в популяциях коренного населения Севера Западной Сибири

Вестник Московского Университета. Серия XXIII: Антропология
Введение. Пополнение и уточнение геногеографической картины гена FTO (rs9939609) является актуальной задачей, поскольку носительство аллеля A*FTO ассоциировано с повышенным риском развития ожирения, сахарного диабета 2 типа, ишемической болезни сердца ...
Васильева А.А., Козлов А.И., Вершубская Г.Г., Лавряшина М.Б.   +3 more
doaj   +1 more source

FTO rs9939609 polymorphism in non-alcoholic fatty liver disease: Frequency and characteristics of risk genotypes

, 2017
FTO rs9939609 polymorphism in non-alcoholic fatty liver disease: Frequency and characteristics of risk ...
S Sood (10360826), A Reddy (12709148), MC Ryan (12507847), SK Roberts (12507844), Elena George (13070892), AC Tierney (14453883), AJ Nicoll (10493168)   +6 more
core  

FTO rs9939609 genotype and behavioral determinants of Mediterranean diet adherence in young women: exploratory insights into potential metabolic relevance. [PDF]

Front Nutr
Obara-Gołębiowska M, Przybyłowicz KE, Danielewicz A, Sawicki T.   +3 more
europepmc   +1 more source

Vigorous Physical Activity Mitigates Susceptibility to Obesity Associated with Risk Genotypes of <i>FTO</i> and <i>MC4R</i>, and <i>SREBF1</i> Is Hypermethylated: A Cross-Sectional Pilot Study. [PDF]

Epigenomes
Chambers J, Erazo Bastidas M, Roscoe CMP, Chidley C, Makkar A, Duggirala A.   +5 more
europepmc   +1 more source

Association between FTO rs9939609 genotype and breast cancer risk after bariatric surgery in the Swedish Obese Subjects study. [PDF]

Sci Rep
Langegård E, Kristensson FM, Andersson-Assarsson JC, Peltonen M, Svensson PA, Jacobson P, Ahlin S, Sjöholm K, Carlsson LMS, Taube M.   +9 more
europepmc   +1 more source

Role of <i>FTO</i> rs9939609 and <i>LEPR</i> rs1137101 Genetic Variants in Gestational Weight Gain and Neonatal Weight Among Pregnant Adolescents. [PDF]

Int J Mol Sci
Sámano R, Martínez-Rojano H, Díaz-Medina A, Monroy-Muñoz IE, Chico-Barba G, Mendoza-Flores ME, Borboa-Olivares H, Zaga-Clavellina V, Gamboa R, Gonzalez-Fernandez MD, Felipe-Hernández Á, Sevilla-Montoya R, Martínez-Juárez A.   +12 more
europepmc   +1 more source

Genetic background of obesity: a case-control study. [PDF]

Hormones (Athens)
Kalesis K, Roidοs P, Nikolopoulos V, Katsiki N, Kotsa K, Koufakis T.   +5 more
europepmc   +1 more source