Results 91 to 100 of about 4,732 (207)

The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China

BMC Medical Genetics, 2010
Background Previous genome-wide association studies for type 2 diabetes susceptibility genes have confirmed that a common variant, rs9939609, in the fat mass and obesity associated (FTO) gene region is associated with body mass index (BMI) in European ...
Lindpaintner Klaus, Hou Dongqing, Cheng Hong, Wu Lijun, Zhao Xiaoyuan, Liu Xin, Zhang Meixian, Shen Yue, Xi Bo, Liu Lisheng, Mi Jie, Wang Xingyu   +11 more
doaj   +1 more source

Age- and sex-dependent association between FTO rs9939609 and obesity-related traits in Chinese children and adolescents. [PDF]

PLoS ONE, 2014
The associations between common variants in the fat mass- and obesity-associated (FTO) gene and obesity-related traits may be age-dependent and may differ by sex.
Meixian Zhang, Xiaoyuan Zhao, Hong Cheng, Liang Wang, Bo Xi, Yue Shen, Dongqing Hou, Jie Mi   +7 more
doaj   +1 more source

Association study of FTO gene single nucleotide polymorphism rs9939609 with body mass and oral microbiome in women from the Zagreb Region [PDF]

, 2016
Pretilost je rastući problem diljem svijeta. Nastaje kao posljedica kronične neravnoteže unosa i potrošnje energije. Etiologija pretilosti je vrlo složena, a procjenjuje se da su genetičke razlike među pojedincima uzrok 40 – 70% razlike u sklonosti ...
Škara, Lucija
core   +1 more source

Association of Allelic Variation in Genes Mediating Aspects of Energy Homeostasis with Weight Gain during Administration of Antipsychotic Drugs (CATIE Study) [PDF]

, 2011
Antipsychotic drugs are widely used in treating schizophrenia, bipolar disorder, and other psychiatric disorders. Many of these drugs, despite their therapeutic advantages, substantially increase body weight. We assessed the association of alleles of 31
Hemant K Tiwari, Amit ePatki, Jeffrey eLieberman, T. Scott eStroup, David B Allison, David B Allison, David B Allison, Rudolph L Leibel, Wendy K Chung   +8 more
core   +1 more source

Uncovering the Causal Link Between Obesity‐Associated Genes and Multiple Sclerosis: A Systematic Literature Review

Brain and Behavior, Volume 15, Issue 4, April 2025.
This systematic literature review explores the influence of six obesity‐associated genes on multiple sclerosis (MS) risk and progression, revealing significant genetic underpinnings and potential pathways for MS pathogenesis and treatment. ABSTRACT Background: Multiple sclerosis (MS) is a multifaceted neurodegenerative disorder influenced by genetics ...
Ali Jafari, Sara Khoshdooz, Melika Arab Bafrani, Farnush Bakhshimoghaddam, Hamid Abbasi, Saeid Doaei   +5 more
wiley   +1 more source

Type 2 Diabetes in Taiwan: Unmasking Influential Factors Through Advanced Predictive Modeling

Journal of Diabetes Research, Volume 2025, Issue 1, 2025.
Background: Type 2 diabetes (T2D) is influenced by lifestyle, genetics, and environmental conditions. By utilizing machine learning techniques, we can enhance the precision of T2D risk prediction by analyzing the complex interactions among these variables.
Shih-Tsung Chang, Ying-Hsiang Chou, Oswald Ndi Nfor, Ji-Han Zhong, Chien-Ning Huang, Yung-Po Liaw, Mallikarjuna Korivi   +6 more
wiley   +1 more source

FTO Genotype and 2-Year Change in Body Composition and Fat Distribution in Response to Weight-Loss Diets: The POUNDS LOST Trial [PDF]

, 2014
Recent evidence suggests that the fat mass and obesity-associated gene (FTO) genotype may interact with dietary intakes in relation to adiposity. We tested the effect of FTO variant on weight loss in response to 2-year diet interventions.
Hu, Frank B., Qi, Lu, Qi, Qibin, Sacks, Frank M., Zhang, Cuilin, Zhang, Xiaomin   +5 more
core   +1 more source

Association of Genetic, Environmental, and Nutritional Factors With Metabolic Phenotypes of Obesity: A Scoping Review

Journal of Obesity, Volume 2025, Issue 1, 2025.
Background: There are inconsistent findings regarding the different metabolic phenotypes of obesity and associated risk factors. This scoping review aims to provide a comprehensive summary of the literature that has evaluated the relationship between genetic, environmental, and nutritional factors and metabolic heterogeneity in obese and normal‐weight ...
Haniyeh Danesh Doost, Milad Nasiri Jounaghani, Roya Riahi, Motahar Heidari-Beni, Mohsen Hosseini, Fariborz Sharifianjazi, Roya Kelishadi, Shashank Kaushik   +7 more
wiley   +1 more source

Interaction between FTO gene variants and lifestyle factors on metabolic traits in an Asian Indian population [PDF]

, 2016
Background Lifestyle factors such as diet and physical activity have been shown to modify the association between fat mass and obesity–associated (FTO) gene variants and metabolic traits in several populations; however, there are no gene-lifestyle ...
AE Taylor, C Ortega-Azorin, CJ Willer, CS Yajnik, D Corella, Dhanasekaran Bodhini, E Sonestedt, EK Speliotes, G Radhika, G Stratigopoulos, H Fujii, H Li, J Stevens, JP Bradfield, JS Kooner, Julie A. Lovegrove, K Ramya, K. Ramya, Karani S. Vimaleswaran, KG Alberti, KS Vimaleswaran, KS Vimaleswaran, KS Vimaleswaran, KS Vimaleswaran, KS Vimaleswaran, KS Vimaleswaran, KS Vimaleswaran, KS Vimaleswaran, KS Vimaleswaran, M Deepa, N Roswall, N. Lakshmipriya, NJ Timpson, PC Hallal, Q Qi, Q Qi, R Sicree, R Villegas, R. Mohan Anjana, Replication DIG, Meta-analysis C, Asian Genetic Epidemiology Network Type 2 Diabetes C, South Asian Type 2 Diabetes C, Mexican American Type 2 Diabetes C, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples C, RM Anjana, RM Anjana, S Liu, S Narayan, Sanjay Kinra, SD Rees, SK Vasan, SR Cole, T Lappalainen, TM Frayling, TO Kilpelainen, TO Kilpelainen, V Mohan, V Mohan, V Mohan, V Mohan, V Sudha, Vasudevan Sudha, Venkatesan Radha, Viswanathan Mohan, World Health Organisation WPR, WT Friedewald   +61 more
core   +3 more sources

Genetic Landscape of Obesity in Children: Research Advances and Prospects

Journal of Obesity, Volume 2025, Issue 1, 2025.
Obesity is a chronic metabolic disease characterized by excessive accumulation or uneven distribution of fat in the body, which poses a serious threat to health. Obesity significantly increases the risk of developing сonditions such as type 2 diabetes, coronary heart disease, hypertension, obstructive sleep apnea, and some types of cancer.
Rita Khusainova, Ildar Minniakhmetov, Olga Vasyukova, Bulat Yalaev, Ramil Salakhov, Darya Kopytina, Raisat Guseinova, Ekaterina Dobreva, Galina Melnichenko, Ivan Dedov, Natalia Mokrysheva, Claire Stocker   +11 more
wiley   +1 more source