Results 101 to 110 of about 4,732 (207)

FTO lookus ja selle seos rasvumisega [PDF]

, 2016
Kogu genoomi assotsiatsiooniuuringud on edukalt tuvastanud tuhandeid geneetilisi assotsiatsioone väga paljude erinevate haigustega. Paraku ei asu valdav osa seostunud geneetilistest variantidest DNA kodeerivas järjestuses ning nende mõju geenide ...
Mägi, Reedik
core   +2 more sources

Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index [PDF]

, 2015
We are grateful to the families who took part in GS:SFHS, the GPs and Scottish School of Primary Care for their help in recruiting them, and the whole GS team, which includes academic researchers, clinic staff, laboratory technicians, clerical workers ...
A Farmer, AJ Ferrari, AJ Stunkard, BH Smith, CU Onyike, DP Goldberg, HH Maes, JK Kiecolt-Glaser, KL Gunderson, M Kivimaki, M Kivimaki, M, First, MF Dallman, MF Dallman, N Afari, N Vogelzangs, PF Sullivan, RF Krueger, RM Hirschfeld, S Eysenck, S Purcell, SM Purcell, WN Venables   +22 more
core   +5 more sources

Association of Omentin rs2274907 and FTO rs9939609 gene polymorphisms with insulin resistance in Iranian individuals with newly diagnosed type 2 diabetes

Lipids in Health and Disease, 2019
Background Insulin resistance (IR) and fat accumulation in visceral adipose tissue are key players in developing type 2 diabetes (T2D). Several adipose tissue derived-gene polymorphisms are related to higher body mass index (BMI), insulin resistance and ...
Amirhosein Khoshi, Mehdi Kaffash Bajestani, Habibesadat Shakeri, Golnaz Goodarzi, Fatemeh Azizi   +4 more
doaj   +1 more source

Polimorfismo del alelo rs 9939609 en el gen FTO como factor de riesgo para el desarrollo de sobrepeso en niños ecuatorianos en edad pre-escolar [PDF]

, 2017
Obesity and overweight are diseases that have being increasing exponentially in the last years worldwide. There are environmental and genetic factors involved with the development and evolution of this condition.
Cabezas Reyes, María Cristina
core  

Genetic factors in risk assessment for the development of type 2 diabetes mellitus in a small case series [PDF]

, 2011
. Objective: This study aimed to investigate the role of genetic biomarkers in assessing risk for the eventual development of type 2 diabetes mellitus (T2DM).
Abou-Hussein, S., Felice, Alex, Grima, Stephen, Savona-Ventura, Charles   +3 more
core   +1 more source

[Association between FTO gene rs9939609 and adiposity markers in Chilean children].

Revista chilena de pediatria, 2021
Obesity is considered a chronic inflammatory disease with an important genetic component. Although several studies have reported an association between the FTO (fat-mass associated gene) and adiposity in children, there is limited evidence in the Chilean population.To deter mine the association between the polymorphism rs9939609 of the FTO gene and ...
Natalia, Ulloa, Marcelo, Villagrán, Benilde, Riffo, Andrea, Gleisner, Fanny, Petermann-Rocha, Lorena, Mardones, Ana María, Leiva, María Adela, Martínez-Sanguinetti, Carlos, Celis-Morales   +8 more
openaire   +1 more source

Genetic risk factors for body mass index and obesity in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) Study [PDF]

, 2014
Several genome-wide association studies (GWAS) have demonstrated that common genetic variants contribute to obesity. However, studies of this complex trait have focused on ancestrally European populations, despite the high prevalence of obesity in some ...
Buyske, S, Bůžková, P, Carlson, CS, Chen, CTL, Cole, SA, Crawford, DC, Fernández-Rhodes, L, Fesinmeyer, MD, Fowke, JH, Franceschini, N, Glenn, K, Gross, MD, Haiman, CA, Henderson, BE, Hindorff, LA, Howard, BV, Kolonel, LN, Kuller, LH, Le Marchand, L, Li, Q, Li, R, Lim, U, Manson, JE, Matise, TC, Monroe, KR, North, KE, Peters, U, Prentice, RL, Quibrera, PM, Ritchie, MD, Wilkens, LR   +30 more
core   +1 more source

Understanding the Fat Gene Obesity Common Variant FTO rs9939609

Pakistan Journal of Medicine and Dentistry
Obesity, attributable to the interaction of genetic makeup, lifestyle and environment Factors are a multifactorial disease. However, not all people with similar genetics or same environmental setup become obese. Currently, extensive research is being conducted regarding increases in the prevalence of obesity, apparent in many societies, studying their ...
Muhammad Haris Lucky, Saeeda Baig, Zil-e-Rubab   +2 more
openaire   +1 more source

Associations between an Obesity Related Genetic Variant (FTO rs9939609) and Prostate Cancer Risk

PLoS ONE, 2010
Observational studies suggest that obese men have a lower risk of incident prostate cancer, but an increased risk of advanced and fatal cancers. These observations could be due to confounding, detection bias, or a biological effect of obesity. Genetic studies are less susceptible to confounding than observational epidemiology and can suggest how ...
Lewis, S.J., Murad, A., Chen, L.N., Smith, G.D., Donovan, J., Palmer, T., Hamdy, F., Neal, D., Lane, J.A., Davis, M., Cox, A., Martin, R.M.   +11 more
openaire   +6 more sources

Metabolic biomarkers in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction

Сахарный диабет
BACKGROUND: Half of all patients with chronic heart failure (CHF) have preserved ejection fraction (CHF-nEF). The drug’s use effective for treatment of CHF with reduced ejection fraction (CHF-nFV) reduces the hospitalization incidence but does not affect
T. S. Sveklina, S. B. Shustov, S. N. Kolyubayeva, A. N. Kuchmin, V. A. Kozlov, E. V. Smirnova, A. V. Zharkov   +6 more
doaj   +1 more source