Results 111 to 120 of about 4,732 (207)

Association between fat mass and obesity associated (FTO) gene rs9939609 A/T polymorphism and polycystic ovary syndrome: a systematic review and meta-analysis

BMC Medical Genetics, 2017
Background Up to now, numerous case-control studies have reported the associations between fat mass and obesity associated (FTO) gene rs9939609 A/T polymorphism and polycystic ovary syndrome (PCOS), however, without a consistent result.
Ai Ling Liu, Hui Jun Xie, Hong Yan Xie, Jun Liu, Jie Yin, Jin Song Hu, Cui Ying Peng   +6 more
doaj   +1 more source

Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study [PDF]

, 2009
International ...
Delphine D Fradin, M Daniele Fallin
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Fat phenotype, associated factors and rs9939609 polymorphism of the FTO gene

Revista Brasileira de Cineantropometria e Desempenho Humano, 2010
The purpose of this work was to review the main results of studies that have analysed the relationship between the rs9939609 single nucleotide polymorphism (SNP) of the FTO gene and the manifestation of overweight/obesity with its associated co-morbidity,
William Alves Lima, Maria Fátima Glaner, Aline Pic Taylor   +2 more
doaj   +1 more source

An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images. [PDF]

Understanding how genetics influences obesity, brain activity and eating behaviour will add important insight for developing strategies for weight-loss treatment, as obesity may stem from different causes and as individual feeding behaviour may depend on
Batterink, Beaver, Boutelle, Brooks, Carver, Cole, Delgado, Dietrich, Dina, Fiset, Frayling, Frederiksen, Fredriksson, Gearhardt, Gearhardt, Gerlach, Goldstone, Groot, Heni, Jastreboff, Karra, Kullmann, Leech, Lê, Maldjian, Meule, Olszewski, Schienle, Scuteri, Sevgi, Singh, Speakman, Sällman Almén, Tomasi, Tung, Voigt, Volkow, Yeo, Yu, Zhang, Zhu   +40 more
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Body mass index and health care utilization in diabetic and nondiabetic individuals. [PDF]

, 2015
BackgroundAlthough controversial, most studies examining the relationship of body mass index (BMI) with mortality in diabetes suggest a paradox: the lowest risk category is above normal weight, versus normal weight in nondiabetic persons.
Bertakis, Klea D, Franks, Peter, Jerant, Anthony   +2 more
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Effect of the rs9939609-FTO marker in Mexican adults under nutritional intervention

Revista Mexicana de Endocrinología, Metabolismo y Nutrición
Background: Obesity is a disease importantly influenced by genetic factors. The rs9939609 variant of the gene associated with fat mass and obesity (FTO) has been associated with weight gain, body mass index (BMI), and influence on the individual response
Diana A. Vela-Vásquez, Ivan Delgado-Enciso, Gilberto Ruiz-de-la-Cruz, Pascuala Ambriz-Morales, Ana Ma. Sifuentes-Rincón   +4 more
doaj   +1 more source

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth

BMC Medical Genetics, 2010
Background Genome-wide association studies found common variants in the fat mass and obesity-associated (FTO) gene associated with adiposity in Caucasians and Asians but the association was not confirmed in African populations.
Dong Yanbin, Treiber Frank A, Stallmann-Jorgensen Inger S, Gutin Bernard, Lagou Vasiliki, Zhu Haidong, Liu Gaifen, Snieder Harold   +7 more
doaj   +1 more source

FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs [PDF]

, 2008
Background FTO is a gene located in chromosome region 16q12.2. Recently two studies have found associations of several single nucleotide polymorphisms (SNPs) in FTO with body mass index (BMI) and obesity, particularly rs1421085, rs17817449, and rs9939609.
R Arlen Price, Wei-Dong Li, Hongyu Zhao, AA Hedley, KM Flegal, TM Frayling, C Dina, CH Andreasen, A Scuteri, A Peeters, H Li, J Ohashi, SF Field, J Ott, RS Spielman, GR Abecasis, J Wessel, T Gerken   +17 more
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m6a RNA methylation: the implications for health and disease [PDF]

, 2014
The recent resurgence of interest in m6a has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification.
McGuinness, D., Mcguinness, D.H.
core   +1 more source

Influence of FTO rs9939609 polymorphism on appetite, ghrelin, leptin, IL6, TNFα levels, and food intake of women with morbid obesity

Diabetes, Metabolic Syndrome and Obesity, 2018
Fernanda Cristina Carvalho Mattos Magno,1 Helena Chrispim Guaraná,1 Ana Carolina Proença Fonseca,2 Giselda Maria Kalil Cabello,2 João Régis Ivar Carneiro,3 Aline Pereira Pedrosa,1 Ana Carolina Ximenes,1 Eliane Lopes Rosado1 ...
Magno FCCM, Guaraná HC, Fonseca ACP, Cabello GMK, Carneiro JRI, Pedrosa AP, Ximenes AC, Rosado EL   +7 more
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