Results 61 to 70 of about 4,732 (207)

Polymorphisms in FTO, TMEM18 and PCSK1 are associated with BMI in southern Chinese population [PDF]

, 2014
The article discusses a study which aimed to examine the association between body mass index and several genes, including FTO, TMEM18 and PCSK1, by genotyping the previously reported 11 single-nucleotide polymorphism (SNP) in southern Chinese.
Chen, J, Huang, Q, Xu, A, Yang, M, Zhao, K   +4 more
core   +1 more source

Lifestyle factors modify obesity risk linked to PPARG2 and FTO variants in an elderly population: a cross-sectional analysis in the SUN Project. [PDF]

, 2012
Genetic factors may interact with lifestyle factors to modify obesity risk. FTO and PPARG2 are relevant obesogenes. Our aim was to explore the effect of Pro12Ala (rs1801282) of PPARG2 and rs9939609 of FTO on obesity risk and to examine their interaction ...
Galbete, C. (Cecilia), Guillen-Grima, F. (Francisco), Marti, A. (Amelia), Martinez, J.A. (José Alfredo), Martinez-Gonzalez, M.A. (Miguel Ángel), Toledo, J. (Jon)   +5 more
core   +1 more source

The Association of Fat-Mass-and Obesity-Associated Gene Polymorphism (rs9939609) With Colorectal Cancer: A Case-Control Study

Frontiers in Oncology, 2021
Background and AimThe association between the rs9939609 polymorphism of fat mass and obesity-associated gene (FTO) and risk of colorectal cancer is controversial.
Maryam Gholamalizadeh, Mohammad Esmail Akbari, Saeid Doaei, Sayed Hossein Davoodi, Bojlul Bahar, Ghasem Azizi Tabesh, Hossein Sadeghi, Melika Razavi Hashemi, Elham Kheyrani, Samira Rastgoo, Azadeh Hajipour, Zahra Aslany, Reza Mirfakhraie, Alireza Mosavi Jarrahi   +13 more
doaj   +1 more source

FTO genotypes (rs9939609 T>A) are Associated with Increased Added Sugar Intake in Healthy Young Adults

Lifestyle Genomics, 2023
Introduction: Single-nucleotide polymorphism (SNP) rs9939609 in the FTO gene has been associated with dietary intake and appetite traits, mainly in participants with obesity; however, it remains widely unexplored in normal weight participants.
Andrea Madrigal-Juarez, Erika Martínez-López, Tania Sanchez-Murguia, Lisset Magaña-de la Vega, Roberto Rodriguez-Echevarria, Maricruz Sepulveda-Villegas, Rafael Torres-Valadez, Nathaly Torres-Castillo   +7 more
doaj   +1 more source

Association of FTO and PPARG polymorphisms with obesity in Portuguese women [PDF]

, 2013
Purpose: We evaluated the association between risk of obesity in the Portuguese population and two obesity-related single-nucleotide gene polymorphisms: fat-mass and obesity-associated (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma (
Baptista, Pedro Viana, Brito, Miguel, Carlos, Fábio Ferreira, Doria, Gonçalo, Flores, Orfeu, Silva-Nunes, José, Veiga, Luísa   +6 more
core   +1 more source

The FTO gene rs9939609 obesity-risk allele and loss of control over eating [PDF]

The American Journal of Clinical Nutrition, 2009
Children with rs9939609 FTO variant alleles (homozygous = AA and heterozygous = AT) are predisposed to greater adiposity than are those with 2 wild-type alleles (TT).Because FTO is highly expressed in hypothalamic regions that are important for appetite, FTO genotype may affect energy balance by influencing eating behavior. Loss of control (LOC) eating,
Marian, Tanofsky-Kraff, Joan C, Han, Kavitha, Anandalingam, Lauren B, Shomaker, Kelli M, Columbo, Laura E, Wolkoff, Merel, Kozlosky, Camden, Elliott, Lisa M, Ranzenhofer, Caroline A, Roza, Susan Z, Yanovski, Jack A, Yanovski   +11 more
openaire   +2 more sources

Association of FTO rs9939609 SNP with Obesity and Obesity- Associated Phenotypes in a North Indian Population [PDF]

Oman Medical Journal, 2016
Objectives: Obesity is a common disorder that has a significant impact on morbidity and mortality. Twin and adoption studies support the genetic influence on variation of obesity, and the estimates of the heritability of body mass index (BMI) is ...
Jai Prakash, Balraj Mittal, Apurva Srivastava, Shally Awasthi, Neena Srivastava   +4 more
doaj   +1 more source

Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis [PDF]

BMC Infectious Diseases, 2014
Obesity is known to affect cell-mediated immune responses. Recent studies have revealed that genetic polymorphisms in the fat mass and obesity associated (FTO) gene are related to human obesity. We hypothesize that this gene may also play a role in the risk of immune-related infectious diseases such as tuberculosis.This case-control study included 1625
Feng, Yan, Wang, Fengliang, Pan, Hongqiu, Qiu, Sangsang, Lü, Jieqiong, Wu, Liang, Wang, Jianming, Lu, Cheng   +7 more
openaire   +2 more sources

A High Intake of Saturated Fatty Acids Strengthens the Association between the Fat Mass and Obesity-Associated Gene and BMI123 [PDF]

, 2011
Evidence that physical activity (PA) modulates the association between the fat mass and obesity-associated gene (FTO) and BMI is emerging; however, information about dietary factors modulating this association is scarce.
Ahmad, Andreasen, Cecil, Chao-Qiang Lai, Corella, Corella, Corella, Daruneewan Warodomwichit, Dina, Dolores Corella, Donna K. Arnett, Edmond K. Kabagambe, Frayling, Hardy, Hasselbalch, Hennig, Hotta, Hubáček, Jacobsson, Jonsson, Jose M. Ordovas, Karasawa, Katherine L. Tucker, Lai, Lai, Larder, Laurence D. Parnell, Lee, Lee, Legry, Li, Liu, Michael Tsai, Ohashi, Paul N. Hopkins, Peeters, Qi, Rampersaud, Ruiz, Scuteri, Smith, Sonestedt, Subar, Tan, Thompson, Timpson, Tucker, Vimaleswaran, Walley, Willett, Wing, Yu-Chi Lee   +51 more
core   +1 more source

Implications of Genetic Elements on Type 2 Diabetes Mellitus Pathogenesis and Management

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
Genetic variations in T2DM, including key metabolic and insulin‐related genes, influence disease risk, insulin resistance, and drug response. Understanding these polymorphisms enables precision medicine, optimising therapy and improving glycaemic control across diverse populations.
Nokwanda N. Ngcobo, Ntethelelo H. Sibiya
wiley   +1 more source