Trim32 reduces PI3K–Akt–FoxO signaling in muscle atrophy by promoting plakoglobin–PI3K dissociation [PDF]
, 2014 Activation of the PI3K–Akt–FoxO pathway induces cell growth, whereas its inhibition reduces cell survival and, in muscle, causes atrophy. Here, we report a novel mechanism that suppresses PI3K–Akt–FoxO signaling. Although skeletal muscle lacks desmosomes,
Cohen, Shenhav +4 more
core +1 more source
Graft detachment rates in surgeon‐cut and pre‐cut tissue for DSAEK transported in different mediums
Acta Ophthalmologica, Volume 103, Issue 3, Page 281-288, May 2025.Abstract Purpose To analyse graft detachment rates after Descemet stripping automated endothelial keratoplasty (DSAEK) using surgeon‐cut grafts and pre‐cut grafts transported in different mediums. Methods A retrospective study of graft detachment rates including 265 surgeries (240 patients) performed between 2019 and 2023.
Thorbjörg Olafsdottir +4 more
wiley +1 more source
The molecular basis of human retinal and vitreoretinal diseases [PDF]
, 2010 During the last two to three decades, a large body of work has revealed the molecular basis of many human disorders, including retinal and vitreoretinal degenerations and dysfunctions.
Berger, W +2 more
core +1 more source
Clinical &Experimental Ophthalmology, Volume 53, Issue 3, Page 232-245, April 2025.ABSTRACT Corneal dystrophies are a group of predominantly rare inherited disorders. They are by definition bilateral, relatively symmetrical, and without systemic involvement, affecting corneal transparency and/or refraction. Traditional classification of corneal dystrophies is based on slit‐lamp appearance, affected corneal layer and histological ...
Petra Liskova +3 more
wiley +1 more source
The Australian Corneal Graft Registry 2015 Report [PDF]
, 2015 The Australian Corneal Graft Registry (ACGR) opened in May 1985 and has now been operating for 30 years. Over the years, we have collected information on more than 30,000 corneal grafts.
Coster, Douglas John +5 more
core
RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry [PDF]
, 2018 Ciliopathies are a group of genetically heterogeneous disorders, characterized by defects in cilia genesis or maintenance. Mutations in the RPGR gene and its interacting partners, RPGRIP1 and RPGRIP1L, cause ciliopathies, but the function of their ...
Aguirre +68 more
core +3 more sources
Comparison of corneal endothelial mosaic according to the age: the corimmo 3D project [PDF]
, 2016 International audienceAim: The human corneal endothelium is a monolayer of flat hexagonal cells. It is a nearly regular hexagonal tessellation during the first years of life, but with age, becomes less regular in shape and size.
crouzet, Emmanuel +7 more
core +2 more sources
Bullous keratopathy: etiopathogenesis and treatment [PDF]
, 2008 Bullous keratopathy is characterized by corneal stromal edema with epithelial or subepithelial bullae due to cell loss and endothelial decompensation.
Campos, Mauro Silveira de Queiroz +4 more
core +2 more sources
The Australian Corneal Graft Registry 2007 Report [PDF]
, 2007 The Australian Corneal Graft Registry opened in May 1985 and thus has now been in operation for over 22 years. The census date for this report was 01/09/2006. Over the years, we have collected data on more than 18,500 corneal grafts.
Bartlett, Christine Mary +4 more
core
Late-onset Candida keratitis after Descemet stripping automated endothelial keratoplasty : clinical and confocal microscopic report [PDF]
, 2011 Purpose. To report clinical and confocal microscopy features of late-onset Candida albicans keratitis after Descemet stripping automated keratoplasty (DSAEK). Methods.
Arance-Gil, Ángeles +5 more
core +1 more source