Results 81 to 90 of about 8,757 (220)

Retained Descemet’s membrane following penetrating keratoplasty for Fuchs’ endothelial dystrophy: a case report of a post-operative complication

Clinical Ophthalmology, 2013
Katherine McVeigh,1,3,* Kurt Spiteri Cornish,3 Aravind R Reddy,3 Georgios Vakros2,3,* 1Eye Clinic, Royal United Bath Hospital, Bath, UK; 2Birmingham Midland Eye Centre, Birmingham City Hospital, Birmingham, UK; 3Ophthalmology Department, Aberdeen Royal ...
McVeigh K, Spiteri Cornish K, Reddy AR, Vakros G   +3 more
doaj  

Anterior Keratocyte Depletion in Fuchs Endothelial Dystrophy [PDF]

Archives of Ophthalmology, 2011
To determine if keratocyte populations are different in corneas with Fuchs dystrophy compared with control corneas.Eleven corneas excised during penetrating keratoplasty for Fuchs dystrophy and 5 control corneas of eyes enucleated for choroidal melanoma were examined using light microscopy.
Laura A, Hecker, Jay W, McLaren, Lori A, Bachman, Sanjay V, Patel   +3 more
openaire   +2 more sources

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, Volume 7, Issue 1, February 2026.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases. [PDF]

, 2015
The systemic and organ-specific human fibrotic disorders collectively represent one of the most serious health problems world-wide causing a large proportion of the total world population mortality.
Ballater R, Beon M, Bryan N, Butterfield TA, Connolly MK, Desmoulière A, Fallowfield JA, Galván‐Peña S, Gordon S, Goumans M, Hu B, Ito T, Jimenez SA, Korns D, Krieg T, Lassen S, Lech M, Leibovich SJ, Lev B, Mantovani A, Mantovani A, Molumdar K, Nestle FO, O’Doherty U, Piera‐Velazquez S, Poland GA, Rafii R, Rigamonte E, Tacke F, Venbervliet B, Wang Y, Wick G, Wijesundera KK   +32 more
core   +2 more sources

Endothelial keratoplasty versus penetrating keratoplasty for Fuchs endothelial dystrophy [PDF]

Cochrane Database of Systematic Reviews, 2014
Fuchs endothelial dystrophy (FED) is a condition in which there is premature degeneration of corneal endothelial cells. When the number of endothelial cells is reduced to a significant degree, fluid begins to accumulate within the cornea. As a result, the cornea loses its transparency and the individual suffers a reduction in vision.
Mayank A, Nanavaty, Xue, Wang, Alex J, Shortt   +2 more
openaire   +2 more sources

Quality of life and participation after corneal transplantation and potential predictors: A multicenter prospective cohort study

Acta Ophthalmologica, Volume 104, Issue 1, Page 52-64, February 2026.
Abstract Purpose To evaluate the long‐term effect of corneal transplantation on health‐ and vision‐related quality of life, visual functioning, and societal participation, and to assess potential predictors. Methods We conducted a multicenter prospective cohort study in 11 Dutch hospitals and eye clinics.
E. B. M. Elsman, D. Van der Meij, H. P. A. Van der Aa, N. Santana, M. C. Bartels, M. Zaal, Y. Y. Cheng, R. M. M. A. Nuijts, G. H. M. B. Van Rens, R. M. A. Van Nispen   +9 more
wiley   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

Stromal Curvature, Power and Corneal‐Stromal Curvature Ratios From a Hybrid AS‐OCT in Eyes With Keratoconus

Clinical &Experimental Ophthalmology, Volume 54, Issue 1, Page 9-20, January/February 2026.
ABSTRACT Background To characterise stromal curvature and curvature ratios in keratoconus (KCN) using anterior segment OCT, and to evaluate the implications of using single‐, two‐, and three‐surface refractive models for corneal power estimation in ectatic eyes. Methods Retrospective observational study.
Jascha A. Wendelstein, Annabella Ostermaier, Katrin Freller, Arianna Grendele, Giacomo Savini, Catarina Praefke Coutinho, Robert Herber, Nikolaus Luft, Stefan Kassumeh, Achim Langenbucher, Siegfried Priglinger   +10 more
wiley   +1 more source

Telomerase Immortalization of Human Corneal Endothelial Cells Yields Functional Hexagonal Monolayers [PDF]

, 2012
Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose main function is to maintain corneal clarity by regulating corneal hydration. HCEnCs are derived from neural crest and are arrested in the post-mitotic state.
Bonanno, Joseph, Chen, Yuming, Jurkunas, Ula V., Li, Shimin, Nguyen, Tracy T., Schmedt, Thore   +5 more
core   +3 more sources

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

Advanced Therapeutics, Volume 8, Issue 9, September 2025.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source