Results 91 to 100 of about 8,757 (220)
ABSTRACT Background To establish normative values for stromal curvature and its relationships to anterior and posterior curvature. Methods Retrospective observational study. Data were obtained from 75 eyes of cataract surgery patients using a high‐resolution anterior segment optical coherence tomograph (AS‐OCT; MS‐39, CSO).
Jascha A. Wendelstein +7 more
wiley +1 more source
Trim32 reduces PI3K–Akt–FoxO signaling in muscle atrophy by promoting plakoglobin–PI3K dissociation [PDF]
Activation of the PI3K–Akt–FoxO pathway induces cell growth, whereas its inhibition reduces cell survival and, in muscle, causes atrophy. Here, we report a novel mechanism that suppresses PI3K–Akt–FoxO signaling. Although skeletal muscle lacks desmosomes,
Cohen, Shenhav +4 more
core +1 more source
ABSTRACT Introduction We aimed to evaluate biophysical compatibility of corneal endothelial cells in genetically‐engineered (GE) pigs to identify the best candidate for in vivo nonhuman primate (NHP) study and to collect baseline data for future clinical trials from a biological function perspective.
Seung Hyeun Lee +8 more
wiley +1 more source
RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry [PDF]
Ciliopathies are a group of genetically heterogeneous disorders, characterized by defects in cilia genesis or maintenance. Mutations in the RPGR gene and its interacting partners, RPGRIP1 and RPGRIP1L, cause ciliopathies, but the function of their ...
Aguirre +68 more
core +3 more sources
Presbyopia Correction in Lens Replacement Surgery: A Review
ABSTRACT Presbyopia affects approximately 1.8 billion individuals globally, posing significant challenges as life expectancy and near‐vision demands, particularly with mobile phone use, grow. Addressing presbyopia during lens replacement surgery has become a key focus for cataract surgeons, aiming to reduce dependence on corrective eyewear. This review
Benjamin Stern, Damien Gatinel
wiley +1 more source
The molecular basis of human retinal and vitreoretinal diseases [PDF]
During the last two to three decades, a large body of work has revealed the molecular basis of many human disorders, including retinal and vitreoretinal degenerations and dysfunctions.
Berger, W +2 more
core +1 more source
Intrinsic structural disorder in cytoskeletal proteins. [PDF]
Cytoskeleton, the internal scaffold of the cell, displays an exceptional combination of stability and dynamics. It is composed of three major filamentous networks, microfilaments (actin filaments), intermediate filaments (neurofilaments), and ...
Beata Szabo +4 more
core +1 more source
Bullous keratopathy: etiopathogenesis and treatment [PDF]
Bullous keratopathy is characterized by corneal stromal edema with epithelial or subepithelial bullae due to cell loss and endothelial decompensation.
Campos, Mauro Silveira de Queiroz +4 more
core +2 more sources
Major indications for keratoplasty in the eastern province, Saudi Arabia
Purpose: To determine the leading indications for keratoplasty in the Eastern Province of the Kingdom of Saudi Arabia (KSA) over a 5 years period (2005-2010) and to compare these indications with previously published studies.
Khalid Arfaj, Reem Abdulqader
doaj +1 more source
Estudio comparativo entre microscopía confocal y microscopía especular en la valoración del endotelio en córneas con distrofia de Fuchs [PDF]
La distròfia endotelial de Fuchs es caracteritza per la formació de guttas endotelials i en estadis avançats pot induir edema corneal i pèrdua d'agudesa visual. A diferència del microscopi especular, el microscopi confocal té un disseny que permet evitar
Charafeddin, Wissam +2 more
core +1 more source

