Results 131 to 140 of about 3,843 (175)

Associations between measures of oestrogen exposure and severity of Fuchs endothelial corneal dystrophy. [PDF]

BMJ Open Ophthalmol
Petrela RB, Chhetri CD, Najafi A, Zhang Z, A Rinkoski T, Wieben ED, Fautsch MP, Chakraborty S, E Millen A, Patel SP.   +9 more
europepmc   +1 more source

Genetic and Demographic Determinants of Fuchs Endothelial Corneal Dystrophy Risk and Severity. [PDF]

JAMA Ophthalmol
Liu S, Sadan AN, Bhattacharyya N, Zarouchlioti C, Szabo A, Abreu Costa M, Hafford-Tear NJ, Kladny AS, Dudakova L, Ciosi M, Moghul I, Wilkins MR, Allan B, Skalicka P, Hardcastle AJ, Pontikos N, Bunce C, Monckton DG, Muthusamy K, Liskova P, Tuft SJ, Davidson AE.   +21 more
europepmc   +1 more source

The PERK-p38 MAPK Axis Drives Endoplasmic Reticulum Stress-Induced Apoptosis in Fuchs Endothelial Corneal Dystrophy. [PDF]

Invest Ophthalmol Vis Sci
Onishi T, Yuasa T, Ueda N, Miyadai K, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N, Okumura N.   +8 more
europepmc   +1 more source

Fuchs Endothelial Corneal Dystrophy [PDF]

Ocular Surface, 2010
Fuchs endothelial corneal dystrophy (FECD) is characterized by progressive loss of corneal endothelial cells, thickening of Descement's membrane and deposition of extracellular matrix in the form of guttae. When the number of endothelial cells becomes critically low, the cornea swells and causes loss of vision. The clinical course of FECD usually spans
Ula V Jurkunas
exaly   +4 more sources

Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis

Progress in Retinal and Eye Research, 2021
Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal endothelial dystrophy and the leading indication for corneal transplantation worldwide. FECD is characterized by the progressive decline of corneal endothelial cells (CECs) and the formation of extracellular matrix (ECM) excrescences in Descemet's membrane (DM), called guttae,
Adam Wylęgała, Stephan Ong Tone, Myriam Bohm   +2 more
exaly   +4 more sources

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Fuchs endothelial corneal dystrophy

Vestnik oftal'mologii, 2017
Fuchs endothelial dystrophy is a severe disease characterized by slowly progressing bilateral asymmetric corneal edema usually seen in elderly patients. The primary purpose of treatment is to minimize edema-related symptoms, such as ocular discomfort and visual acuity loss.
S V, Trufanov, E P, Salovarova, S A, Malozhen, R Z, Bagh   +3 more
openaire   +2 more sources

Corneal changes in Fuchs endothelial corneal dystrophy and bullous keratopathy

Russian Journal of Archive of Pathology, 2023
Objective. Evaluation of structural and immunohistochemical features of cornea in Fuchs endothelial corneal dystrophy (FECD) and bullous keratopathy (BK). Material and methods. Group 1 — 44 patients (46 eyes) with FECD, group 2 — 42 patients (42 eyes) with BK. All patients underwent keratoplasty.
T.A. Demura, N.V. Fisenko, G.A. Osipyan, M.A. Afonina   +3 more
openaire   +2 more sources

Fuchs Endothelial Corneal Dystrophy and Mitochondria

Cornea, 2018
Abstract: Fuchs endothelial corneal dystrophy (FECD) is a bilateral progressive corneal endothelial disease characterized by guttae, which present as partial Descemet membrane thickening, inducing corneal edema at the final stage. Oxidative stress has been reported to play an important role in the pathogenesis of FECD.
openaire   +2 more sources

Regenerative Therapy for Fuchs Endothelial Corneal Dystrophy

Cornea, 2018
Purpose: Fuchs endothelial corneal dystrophy (FECD) is an acquired corneal endotheliopathy and is one of the most common indications for corneal transplantation surgery worldwide. Endothelial keratoplasty (EK) is the most popular form of corneal transplantation for FECD. In standard EK surgery, the patient's corneal endothelium
Yu Qiang, Soh, Jodhbir S, Mehta
openaire   +2 more sources