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The genetic basis of fuchs endothelial corneal dystrophy.
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Fuchs endothelial corneal dystrophy
Vestnik oftal'mologii, 2017Fuchs endothelial dystrophy is a severe disease characterized by slowly progressing bilateral asymmetric corneal edema usually seen in elderly patients. The primary purpose of treatment is to minimize edema-related symptoms, such as ocular discomfort and visual acuity loss.
S V, Trufanov +3 more
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Corneal changes in Fuchs endothelial corneal dystrophy and bullous keratopathy
Russian Journal of Archive of Pathology, 2023Objective. Evaluation of structural and immunohistochemical features of cornea in Fuchs endothelial corneal dystrophy (FECD) and bullous keratopathy (BK). Material and methods. Group 1 — 44 patients (46 eyes) with FECD, group 2 — 42 patients (42 eyes) with BK. All patients underwent keratoplasty.
T.A. Demura +3 more
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Endothelial viral inclusions in Fuchs' corneal dystrophy
Human Pathology, 1987A case of Fuchs' corneal dystrophy is presented. The patient, a 70-year-old white woman, had bilateral decreasing vision, especially while reading and driving at night. Clinical features were characteristic of Fuchs' corneal dystrophy. Ultrastructural studies demonstrated findings in Descemet's membrane typical of those previously reported with ...
S I, Roth, E L, Stock, R, Jutabha
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Regenerative Therapy for Fuchs Endothelial Corneal Dystrophy
Cornea, 2018Purpose: Fuchs endothelial corneal dystrophy (FECD) is an acquired corneal endotheliopathy and is one of the most common indications for corneal transplantation surgery worldwide. Endothelial keratoplasty (EK) is the most popular form of corneal transplantation for FECD. In standard EK surgery, the patient's corneal endothelium
Yu Qiang, Soh, Jodhbir S, Mehta
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Cancer Risk in Patients With Fuchs Endothelial Corneal Dystrophy
Cornea, 2021Purpose: The purpose of this study is to quantify cancer risk in patients with Fuchs endothelial corneal dystrophy (FECD). Methods: Using the 2014 to 2016 Medicare Limited 5% Data Sets—Carrier Line File, US Medicare fee-for-service beneficiaries (aged 65 years or older) with FECD ...
Timothy T. Xu +4 more
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Fuchs Endothelial Corneal Dystrophy and Mitochondria
Cornea, 2018Abstract: Fuchs endothelial corneal dystrophy (FECD) is a bilateral progressive corneal endothelial disease characterized by guttae, which present as partial Descemet membrane thickening, inducing corneal edema at the final stage. Oxidative stress has been reported to play an important role in the pathogenesis of FECD.
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The Molecular Basis of Fuchs’ Endothelial Corneal Dystrophy
Molecular Diagnosis & Therapy, 2019Fuchs' endothelial corneal dystrophy (FECD) is a common disease resulting from corneal endothelial cell dysfunction. It is inherited in an autosomal dominant fashion with incomplete penetrance, and with a female bias. Approximately half of cases occur sporadically, and the remainder are familial. Early and late-onset forms of the disease exist.
Jie Zhang +2 more
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Diurnal Variation in Corneal Edema in Fuchs Endothelial Corneal Dystrophy
American Journal of Ophthalmology, 2019The extent of diurnal variation in corneal edema in Fuchs dystrophy is unknown. We measured corneal thickness and posterior profile over the course of the day using Scheimpflug imaging.Prospective cohort study.Participants with clinically advanced Fuchs dystrophy eyes undergoing endothelial keratoplasty and participants with healthy corneas were ...
Marianne Fritz +6 more
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Genotyping methods for Fuchs corneal endothelial dystrophy
Journal Français d'OphtalmologieFuchs endothelial corneal dystrophy (FECD) is a genetic degenerative disease characterized by the progressive degradation of the corneal endothelium, often leading to vision loss. It is the leading cause of corneal transplantation in the Western world. FECD is more common in Europe and the United States, particularly among women.
D. Onitiu +9 more
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