Results 191 to 200 of about 17,367 (263)

Targeted nanoparticle-mediated Co-delivery of IFITM3 KO and ponatinib reverses TKI resistance in chronic myeloid leukemia. [PDF]

Front Pharmacol
Feng Z, Ma Y, Hu J, Wang Y, Wang K, Yang Y, Wu Q, Lou J, Shi R, Xu K, Yang W, Li L, Tu L, Cheng L.   +13 more
europepmc   +1 more source

Fucoidan: Structure and Bioactivity [PDF]

Molecules, 2008
Fucoidan refers to a type of polysaccharide which contains substantial percentages of L-fucose and sulfate ester groups, mainly derived from brown seaweed.
Ruixiang Zhao
exaly   +5 more sources

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Fucoidan and its derivatives: From extraction to cutting-edge biomedical applications

Carbohydrate Polymers
Fucoidan, a sulfated polymeric carbohydrate isolated from various marine brown algae, has attracted the interest of biomedical scientists because of its unique structural features and extensive spectrum of biological activity.
Marwa M Kamil, Mastafa H Al-Musawi
exaly   +2 more sources

Advances in fucoidan and fucoidan oligosaccharides: Current status, future prospects, and biological applications.

Carbohydrate Polymers
Sulfated polysaccharides (SPS) derived from seaweeds are precious bioactive compounds of diverse biological activities. Fucoidan is a complex SPS composed of L-fucose and sulfate groups, can be extracted from brown seaweeds, as well as microbial, insect,
H. Hamouda, Tang Li, S. Shabana, A. Hashem, Heng Yin   +4 more
semanticscholar   +3 more sources

Therapies from Fucoidan: New Developments

Marine Drugs, 2019
Since our last review in 2015, the study and use of fucoidan has extended in several research areas. Clinical use of fucoidan for the treatment of renal disease has become available and human safety studies have been undertaken on radiolabeled fucoidan ...
J Helen Fitton, Damien Stringer
exaly   +2 more sources

Development of a Fucoidan-Specific Antibody and Measurement of Fucoidan in Serum and Urine by Sandwich ELISA

Bioscience, Biotechnology and Biochemistry, 2010
Fucoidan exhibits various biological properties. We raised a novel antibody against fucoidan extracted from Cladosiphon okamuranus and developed a sandwich ELISA method to measure fucoidan. The fucoidan antibody was specific and did not cross-react with other polysulfated polysaccharides.
Yoshiharu Tokita, Takeaki Nagamine, Masahiko Iha   +2 more
exaly   +3 more sources

Fucoidan Ameliorated Dextran Sulfate Sodium-Induced Ulcerative Colitis by Modulating Gut Microbiota and Bile Acid Metabolism.

Journal of Agricultural and Food Chemistry, 2022
Gut dysbiosis and bile acid (BA) metabolism disturbance are involved in the pathogenesis of ulcerative colitis. This study aimed to investigate the effect of fucoidan on BA metabolism and gut microbiota in dextran sulfate sodium-induced colitis mice. Our
Xiaoxia Liu, Yun-Hui Zhang, Wanhua Li, Bowei Zhang, Jia Yin, Sijing Liuqi, Jin Wang, Bo Peng, Shuo Wang   +8 more
semanticscholar   +1 more source

Fucoidan mitigates gastric ulcer injury through managing inflammation, oxidative stress, and NLRP3-mediated pyroptosis.

International Immunopharmacology, 2023
This study aimed to elucidate the gastro-protective effect of fucoidan against ethanol-induced gastric ulcer mediated via NLRP3-induced pyroptosis as an underlying mechanism, not yet assessed in prior research.
H. Selim, W. Negm, M. Hawwal, I. A. Hussein, E. Elekhnawy, R. Ulber, A. Zayed   +6 more
semanticscholar   +1 more source