Results 191 to 200 of about 75,164 (361)

A Leishmania infantum FML-ELISA for the Detection of Symptomatic and Asymptomatic Canine Visceral Leishmaniasis in an Endemic Area of Iran [PDF]

open access: yes
Background: Visceral leishmaniasis (VL) is caused by Leishmania infantum in Mediterranean basin and is an endemic disease in some parts of Iran. Canines are the main reservoirs of VL in most of the endemic areas.
بهلولی, شهاب   +6 more
core  

Genetic Locus and Structural Characterization of the Biochemical Defect in the O-Antigenic Polysaccharide of the Symbiotically Deficient \u3cem\u3eRhizobium etli\u3c/em\u3e Mutant, CE166 [PDF]

open access: yes, 2003
The O-antigen polysaccharide (OPS) of Rhizobium etli CE3 lipopolysaccharide (LPS) is linked to the core oligosaccharide via an N-acetylquinovosaminosyl (QuiNAc) residue.
Box, Jodie M.   +3 more
core   +1 more source

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij   +7 more
wiley   +1 more source

Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation. [PDF]

open access: yes, 1983
We are investigating the hypothesis that carbohydrate-binding molecules on the cell surface are involved in the recirculation of lymphocytes from the bloodstream into lymphoid organs.
Rosen, SD, Stoolman, LM
core   +1 more source

Highly efficient transgene‐free ErCas12a RNP‐protoplast genome editing and single‐cell regeneration in Nicotiana benthamiana for glyco‐engineering

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana serves as a unique platform for biopharmaceutical production, offering advantages such as efficient and scalable protein synthesis. In addition, custom N‐glycans can be engineered on biopharmaceutical glycoproteins. Yet, plant‐native glycosyltransferases and glycoside hydrolases need to be removed to prevent undesired ...
Lukas C. Blumberg   +8 more
wiley   +1 more source

Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer   +2 more
wiley   +1 more source

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy