Results 1 to 10 of about 955,216 (365)
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
Cell, 2020 The recent emergence of a novel coronavirus associated with an ongoing outbreak of pneumonia (Covid-2019) resulted in infections of more than 72,000 people and claimed over 1,800 lives.
M Alejandra Tortorici +2 more
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P-Glycoprotein: One Mechanism, Many Tasks and the Consequences for Pharmacotherapy of Cancers
Frontiers in Oncology, 2020 P-glycoprotein or multidrug resistance protein (MDR1) is an adenosine triphosphate (ATP) binding cassette transporter (ABCB1) intensely investigated because it is an obstacle to successful pharmacotherapy of cancers.
Anna Seelig
exaly +2 more sources
A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin
Journal of Cell Biology, 1993 The dystrophin-glycoprotein complex was tested for interaction with several components of the extracellular matrix as well as actin. The 156-kD dystrophin-associated glycoprotein (156-kD dystroglycan) specifically bound laminin in a calcium-dependent ...
Kevin P Campbell, J M Ervasti
exaly +2 more sources
Characterizing Intact IgA2 Antibody and Its Size Variants Using Native Mass Spectrometry and a Tandem MS-based Charge Reduction Approach [PDF]
Zhipu Xuebao, 2022 Characterization of protein structures at multiple levels plays an essential role in study on protein functions. Structural analysis at the intact protein or intact complex level allows access of information on aspects including level of post ...
CHEN Qing-rong;CHAIHU Ling-xiao;CHEN Tao;WANG Guan-bo
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Frontiers in Endocrinology, 2021 It is well accepted that pituitary follitropin is secreted into the circulation as a mixture of variants, which differ not in primary structure but rather at the level of glycosylation.
James A. Dias, Alfredo Ulloa-Aguirre
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Recent Developments in Deciphering the Biological Role of Plant Complex N-Glycans
Frontiers in Plant Science, 2022 Asparagine (N)-linked protein glycosylation is a ubiquitous co- and posttranslational modification which has a huge impact on the biogenesis and function of proteins and consequently on the development, growth, and physiology of organisms.
Richard Strasser
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Viruses, 2022 Human T-cell immunoglobulin mucin 1 (hTIM-1) is known to promote cellular entry of enveloped viruses. Previous studies suggested that the polymorphisms of hTIM-1 affected its function.
Takanari Hattori +5 more
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Frontiers in Microbiology, 2020 The development of a safe and efficient multivalent vaccine has great prospects for application. Both rabies virus (RABV) and canine distemper virus (CDV) are highly infectious antigens, causing lethal diseases in domestic dogs and other carnivores ...
Lina Yan +9 more
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Heliyon, 2022 The multidrug resistance phenomenon presents a major threat to the pharmaceutical industry. This resistance is a common occurrence in several diseases and is mediated by multidrug transporters that actively pump substances out of the cell and away from ...
Iman Imtiyaz Ahmed Juvale +3 more
semanticscholar +1 more source
Extensins: Self-Assembly, Crosslinking, and the Role of Peroxidases
Frontiers in Plant Science, 2021 The extensin (EXT) network is elaborated by the covalent intermolecular crosslinking of EXT glycoprotein monomers, and its proper assembly is important for numerous aspects of basic wall architecture and cellular defense.
John W. Mishler-Elmore +8 more
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