Results 21 to 30 of about 955,216 (365)
Frontiers in Immunology, 2019 Respiratory syncytial virus (RSV) is the leading cause of serious respiratory tract disease but there is no licensed RSV vaccine. Immunopathological mechanisms have long been suspected as operating in the development of severe RSV disease and have ...
In Su Cheon +11 more
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Herpes Simplex Virus 1 Entry Glycoproteins Form Complexes before and during Membrane Fusion
mBio, 2022 Herpesviruses—ubiquitous pathogens that cause persistent infections—have some of the most complex cell entry mechanisms. Entry of the prototypical herpes simplex virus 1 (HSV-1) requires coordinated efforts of 4 glycoproteins, gB, gD, gH, and gL.
Zemplen Pataki +2 more
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Saccharomyces uvarum mannoproteins stimulate a humoral immune response in mice
Brazilian Archives of Biology and Technology, 2012 Yeasts discarded in industrial processes can be used as a nutritional supplement and to extract cellular components with biotechnological aims. In this study, the humoral immune response of Swiss mice treated with mannoproteins (MP) from the yeast ...
Fernanda Patrícia Brito Darpossolo +3 more
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Pharmaceuticals, 2022 Monkeypox is a zoonotic contagious disease that has recently re-emerged in different countries worldwide. Due to the lack of an effective treatment that eliminates the virus, there is an urgent need to find effective drugs to stop the spread of the multi-
Hisham N. Altayb
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Frontiers in Microbiology, 2022 Ebola virus (EBOV) causes severe EBOV disease (EVD) in humans and non-human primates. Currently, limited countermeasures are available, and the virus must be studied in biosafety level-4 (BSL-4) laboratories.
Wakako Furuyama +3 more
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Glycoprotein Processing and Glycoprotein Processing Inhibitors [PDF]
Plant Physiology, 1988 Considerable evidence is now accumulating from both in vivo and in vitro studies that the oligosaccharide chains of the plant N-linked glycoproteins undergo modification or processing reactions after the oligosaccharide has been transferred from its lipid-linked oligosaccharide intermediate to the protein.
openaire +2 more sources
Frontiers in Microbiology, 2011 Hantaviruses, of the family Bunyaviridae, are present throughout the world and cause a variety of infections ranging from the asymptomatic to mild and severe hemorrhagic fevers. Hantaviruses are enveloped anti-sense RNA viruses that contain three genomic
D. Fernando eEstrada +3 more
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PLoS Pathogens, 2018 The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 (ACE2) and mediates fusion of the viral and cellular membranes through a pre- to ...
Wenfei Song +3 more
semanticscholar +1 more source
Viruses, 2021 Rodent-borne orthohantaviruses are asymptomatic in their natural reservoir, but they can cause severe diseases in humans. Although an exacerbated immune response relates to hantaviral pathologies, orthohantaviruses have to antagonize the antiviral ...
Giulia Gallo +14 more
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Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Science, 2009 P-glycoprotein (P-gp) detoxifies cells by exporting hundreds of chemically unrelated toxins but has been implicated in multidrug resistance (MDR) in the treatment of cancers.
S. Aller +10 more
semanticscholar +1 more source