Results 31 to 40 of about 874,483 (313)

Electrochemical Impedance Spectroscopy for Investigation of Different Losses in 4-cells Short Stack with Integrated Humidifier and Water Separator [PDF]

Hydrogen, Fuel Cell & Energy Storage, 2016
Electrochemical impedance spectroscopy (EIS) is a suitable and powerful diagnostic testing method for fuel cells (FCs) since it is non-destructive and provides useful information about FC performance and its components. In this study, for the first time,
Ebrahim Alizadeh, Majid Khorshidian, Seyed Majid Rahgoshay, Seyed Hossein Masrori Saadat, Mazaher Rahimi-Esbo   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A case study analysis of system efficiency, viability and energy values of SOFC based fuel cell Micro-CHP for office buildings

, 2015
The built environment is a large contributor to the greenhouse gas emissions. The first step in tackling environmental impact and fuel cost reduction is the minimization of energy losses through introduction of new and more efficient energy conversion ...
Mylona, A., Irvine, John Thomas Sirr, Connor, Paul Alexander, Cassidy, Mark, Tesfai, Alem   +4 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Supervised machine learning with regression for the IRT-T reactor cooling system [PDF]

ITM Web of Conferences
The purpose of this study is to create a machine learning model for the IRT-T reactor cooling system, which can estimate and predict the temperature difference in the secondary circuit.
Kublinskiy Maxim, Smolnikov Nikita, Naymushin Artem   +2 more
doaj   +1 more source

Novel Nafion/Graphitic Carbon Nitride Nanosheets Composite Membrane for Steam Electrolysis at 110 °C

Membranes, 2023
Hydrogen is expected to have an important role in future energy systems; however, further research is required to ensure the commercial viability of hydrogen generation.
Taipu Chen, Bo Lv, Shucheng Sun, Jinkai Hao, Zhigang Shao   +4 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source