Results 51 to 60 of about 11,919,933 (393)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Mediated Fuel Cells: Soluble Redox Mediators and Their Applications to Electrochemical Reduction of O2 and Oxidation of H2, Alcohols, Biomass, and Complex Fuels.

Chemical Reviews, 2020
Mediated fuel cells are electrochemical devices that produce power in a manner similar to that of conventional proton exchange membrane fuel cells (PEMFCs).
C. Anson, S. Stahl
semanticscholar   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Lithium-mediated electrochemical nitrogen reduction: Mechanistic insights to enhance performance

iScience, 2021
Summary: Green synthesis of ammonia by electrochemical nitrogen reduction reaction (NRR) shows great potential as an alternative to the Haber-Bosch process but is hampered by sluggish production rate and low Faradaic efficiency.
Xiyang Cai, Cehuang Fu, Haldrian Iriawan, Fan Yang, Aiming Wu, Liuxuan Luo, Shuiyun Shen, Guanghua Wei, Yang Shao-Horn, Junliang Zhang   +9 more
doaj  

Studies on anode mass composition and cathode flow field design for small-scale to large-scale direct methanol fuel cell stack systems

AIP Advances, 2022
In this research, the performance studies of a single cell Direct Methanol Fuel Cell with three different mass compositions (20%, 40%, and 60%) of platinum at anode infused in NiTiO3/C and multiple cathode flow fields, such as serpentine, parallel, and ...
Thanarajan Kumaresan, Karthikeyan Palaniswamy, Ashley Fly, Senthilarasu Sundaram   +3 more
doaj   +1 more source

Technical and Commercial Challenges of Proton-Exchange Membrane (PEM) Fuel Cells

Energies, 2020
This review critically evaluates the latest trends in fuel cell development for portable and stationary fuel cell applications and their integration into the automotive industry.
A. Alaswad, Abdelnasir Omran, J. R. Sodré, T. Wilberforce, G. Pignatelli, M. Dassisti, A. Baroutaji, A. Olabi   +7 more
semanticscholar   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

FEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni, Florian Csarman, Peicheng Sun, Mirjam Kabel, Roland Ludwig   +4 more
wiley   +1 more source

Methanol Sensor-Less Control Strategy for Direct Methanol Fuel Cell Startup

Frontiers in Energy Research, 2022
It is critical and challenging to start direct methanol fuel cells (DMFCs) from various environmental states to an ideal operating state by a sensor-less method.
Haibo Gan, Haibo Gan, Haibo Gan, Haibo Gan, Hai Sun, Hai Sun   +5 more
doaj   +1 more source