Results 31 to 40 of about 952 (162)

Analysis of aerosol emission and dispersion during the laser cutting of fukushima fuel debris simulants [PDF]

, 2018
International audienceThe general context of the article is related to demonstrate the feasibility of the use of the laser cutting technique for the fuel debris retrieval on the damaged reactors of Fukushima Dai-ichi.
Chagnot, C., Journeau, C., Gelain, Thomas, Damien Roulet, Porcheron, Emmanuel, Peillon, Samuel, Roulet, Damien, Thomas Gelain, Samuel Peillon, Journeau, Christophe, Porcheron, E., Roulet, D., Peillon, S., Gelain, T., Chagnot, Christophe, Christophe Chagnot, Emmanuel Porcheron, Christophe Journeau   +17 more
core   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Implementation and validation of an aerosol collection model by a spray in a CFD code – Application to the scavenging of aerosols emitted during laser cutting operations of fuel debris for the dismantling of the damaged reactors of Fukushima Dai-ichi [PDF]

, 2020
International audienceThe general context of this article is related to the dismantling of the damaged reactors of Fukushima Dai-ichi and more specifically to the use of the laser cutting technique for the fuel debris retrieval on the damaged reactors ...
Chagnot, Christophe, Gelain, Thomas, Porcheron, Emmanuel, Roulet, Damien, Leblois, Yohan, Journeau, Christophe   +5 more
core   +3 more sources

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Phase behavior of oxidized Ce and Gd-doped (U,Zr)O₂ [PDF]

, 2023
Re-criticality analysis of the fuel debris at the Fukushima Dai-ichi Nuclear Power Plant is the key step to ensure the safe retrieval and storage of the fuel debris.
Watanabe, Shiho, Ohishi, Yuji, Muta, Hiroaki, Kurosaki, Ken, Sun, Yifan   +4 more
core   +1 more source

Characterization of neutrons emitted by an expected small amount of fuel debris in a trial retrieval from Fukushima Daiichi Nuclear Power Station

Nuclear Engineering and Design
Taichi Matsumura, Eka Sapta Riyana, Sakamoto Masahiro   +2 more
exaly   +2 more sources

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source

Interim report spent nuclear fuel retrieval system fuel handling development testing [PDF]

, 1997
Fuel handling development testing was performed in support of the Fuel Retrieval System (FRS) Sub-Project at the Hanford Site. The project will retrieve spent nuclear fuel, clean and remove fuel from canisters, repackage fuel into baskets, and load fuel ...
Meeuwsen, P. V., Baker, C. P., Potter, J. D., Smalley, J. T., Jaquish, W. R., Ketner, G. L.   +5 more
core   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source