Results 121 to 130 of about 121,619 (305)

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Prevention and extinguishment of fires involving hypergolic propellants Final report [PDF]

Halon 1301 system effectiveness in prevention and extinguishment of hypergolic propellant ...
Burgess, D. S., Christos, T. A., Cooper, J. C., Kubala, T. A., Martindill, G. H., Miron, Y., Murphy, J. N., Perzak, F. J., Singer, J. M., Zabetakis, M. G.   +9 more
core   +1 more source

Novel reactor technology for chemical-looping combustion [PDF]

, 2006
No ...
Kuipers, J.A.M., Noorman, S., Sint Annaland, M. van   +2 more
core   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Experimental study of the effects of secondary air on the emissions and stability of a lean premixed combustor [PDF]

Tests were run using a perforated plate flameholder with a relatively short attached recirculation zone and a vee gutter flameholder with a relatively long attached recirculation zone.
Raman, R. S. V., Roffe, G.
core   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Energy efficient engine sector combustor rig test program [PDF]

Under the NASA-sponsored Energy Efficient Engine program, Pratt & Whitney Aircraft has successfully completed a comprehensive combustor rig test using a 90-degree sector of an advanced two-stage combustor with a segmented liner.
Dubiel, D. J., Greene, W., Sundt, C. V., Tanrikut, S., Zeisser, M. H.   +4 more
core   +1 more source

Three-dimensional simulation of a new cooling strategy for proton exchange membrane fuel cell stack using a non-isothermal multiphase model [PDF]

, 2019
In this study, a new cooling strategy for a proton exchange membrane (PEM) fuel cell stack is investigated using a three-dimensional (3D) multiphase non-isothermal model.
Jiao, K, Wang, Y, Yuan, H, Zhang, G
core  

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Charge Stratification and Fuel/Air Ratio Effect on theEfficiency of (ICADE) I. C. Engine Cycle

Al-Khawarizmi Engineering Journal, 2011
The Isolated Combustion and Diluted Expansion (ICADE) internal combustion engine cycle combines the advantages of constant volume combustion of the Otto cycle with the high compression ratio of the Diesel cycle.
Hayder Abed Dhahad
doaj   +2 more sources