This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan +17 more
wiley +1 more source
Photothermal solar assisted Madhuca diethyl ether fuel processing for LHR engines with AI-based performance and yield prediction. [PDF]
Dubey R +5 more
europepmc +1 more source
This study presents a transferable modeling framework for carbon capture using aluminosilicates, integrating Universal Isotherm Modeling with experimental data. It reveals how ultramicropores, alumina content, and amine functionalization influence CO2 adsorption energetics.
Pooja Anil Kumar Nair +4 more
wiley +1 more source
Trajectory optimization for auxiliary power unit operation of an extender range electric vehicle. [PDF]
Yang Y, Tian J, Jia B.
europepmc +1 more source
Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
Experimental Investigation and Artificial Intelligence-Based Modeling of Novel Biodiesel Fuels Containing Hybrid Nanoparticle Additives. [PDF]
Uyar MM, Demirpolat AB, Çıtlak A.
europepmc +1 more source
Spatial Engineering of Gas Diffusion Layers Overcomes Mass Transport Limitations in Fuel Cells
ABSTRACT Mass transport limitations at high current densities hinder polymer electrolyte fuel cell (PEFC) performance due to inefficient water management and reactant distribution. Gas diffusion layer (GDL) perforation offers a potential solution as an alternative to complex flow‐field modifications.
Shangwei Zhou +12 more
wiley +1 more source
Green Synthesis and Application of Platinum-Based Catalysts for Fuel Cells. [PDF]
Zhang J +7 more
europepmc +1 more source
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Implementation of Modified Effective Butterfly Optimizer in Solving Multi-Objective Pareto Optimal Power Flow Problem with Renewable Uncertainties. [PDF]
Işıker H +6 more
europepmc +1 more source

