Results 81 to 90 of about 238,061 (301)
Alaska Fuel Price Projections 2014-2040 [PDF]
, 2014 The Alaska Fuel Price Projections are developed annually for the Alaska Energy Authority (AEA) for the purpose of estimating the potential costs and benefits of renewable energy projects.
Fay, Ginny +1 more
core
Advanced Science, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang +9 more
wiley +1 more source
Advanced Science, EarlyView.Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou +6 more
wiley +1 more source
AerospaceThis study investigated combustion characteristics of composite fuel grains designed based on a modular fuel unit strategy. The modular fuel unit comprised a periodical helical structure with nine acrylonitrile–butadiene–styrene helical blades.
Junjie Pan +6 more
doaj +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
Advanced Science, EarlyView.An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
One-Dimensional simulation of internal ballistic of a Hybrid Rocket Engine [PDF]
علوم، فناوری و کاربردهای فضاییA one-dimensional code was developed to simulate the performance of hybrid rocket engines. In this code, the conservation equations of mass, momentum and energy are solved in one-dimensional and inviscid form.
Hadi Rezaei
doaj +1 more source
Evidence of rational market valuations for home energy efficiency [PDF]
According to this study, residential real estate markets assign to energy-efficient homes an incremental value that reflects the discounted value of annual fuel savings. The capitalization rate used by homeowners was expected to be 4%-10%, reflecting the
Nevin, Rick, Watson, Gregory
core +1 more source
Instantaneous vehicle fuel consumption estimation using smartphones and Recurrent Neural Networks [PDF]
, 2019 The high level of air pollution in urban areas, caused in no small extent by road transport, requires the implementation of continuous and accurate monitoring techniques if emissions are to be minimized. The primary motivation for this paper is to enable
Fitzpatrick, Michael +2 more
core +1 more source
Advanced Science, EarlyView.Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao +12 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source