Results 41 to 50 of about 748,647 (312)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Miniature fuel-cell system complete with on-demand fuel and oxidant supply [PDF]

Journal of Power Sources, 2015
© 2014 Elsevier B.V. The size of a functioning system rather than the individual components determines the success of many miniaturization efforts. While most of the existing micro fuel-cell research has been focusing on the fuel-cell stack, our approach has been to systematically eliminate all the ancillary components with the goal of miniaturizing ...
Janet I. Hur, Chang-Jin Kim
openaire   +3 more sources

Enhancing fuel burning efficiency by regulate spark plug voltage supply [PDF]

, 2013
Nowadays, fuel consumption, fuel efficiency and fuel economy is number one priority for people. The need to reduce fuel consumption is because oil reserves are running low and the cost of gasoline will only increase day by day.
Mohd Ariffin, Maslina
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Algebraic observer design for PEM fuel cell system [PDF]

, 2016
© 20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new ...
Baroud, Zakaria, Benalia, Atallah, Gazzam, Noureddine, Ocampo-Martínez, Carlos   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Моделювання процесу паливоподавання в енергоблоці мініелектростанції ДГУ-315 [PDF]

, 2010
The mathematical model of fuel supply process and transients in the closed system of automatic control of fuel supply of minipower station DGU-315 power unit is ...
Александров, Євген Євгенович, Александрова, Тетяна Євгенівна, Костяник, Ірина Віталіївна   +2 more
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

A Review of Energy Management Strategy for Hydrogen-Electricity Hybrid Power System Based on Control Target

发电技术, 2023
Hydrogen fuel cells, as the energy supply device, have received a lot of attention because of their high energy density and low carbon emission characteristics.
WANG Bofei, XIAO Haozhe, LI Guohao, XIU Wenheng, MO Yunhao, ZHU Mingjie, WU Zhen   +6 more
doaj   +1 more source