Results 71 to 80 of about 6,982,826 (358)

The Politics of Bridge Building: The Long Wait for the Tees (Newport) Bridge [PDF]

open access: yes, 2011
The Tees (Newport) Bridge officially opened in February 1934 to much fanfare and public celebration, the event receiving extensive local, regional and national media attention.
Warwick, Tosh   +2 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Monitoring Bridge Dynamic Behaviour Using an Instrumented Two Axle Vehicle

open access: yes, 2012
Bridge & Infrastructure Research in Ireland 2010 (BRI 10), Cork, 2-3 September 2010Highway structures such as bridges are subject to continuous degradation primarily due to ageing, loading and environmental factors.
McGetrick, P.   +3 more
core  

Evaluation of Bridge Replacement Alternatives for the County Bridge System, HR-365 August 1994 [PDF]

open access: yes, 1994
Recent reports have indicated that 23.5 percent of the nation's highway bridges are structurally deficient and 17.7 percent are functionally obsolete. A significant number of these bridges are on the Iowa county road system.

core  

105 years with the interstate bridge

open access: yes, 2022
The Interstate Bridge opened on February 14, 1917 amid much fanfare. It cost travelers -- both vehicles and horses! -- five cents to cross the bridge. There were two lanes of traffic, one in each direction, as well as a streetcar.

core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Low-Energy Protection System for DC Grids Based on Full-Bridge MMC Converters

open access: yesIEEE Transactions on Power Delivery, 2018
This paper studies protection and control methods for a large dc grid based solely on full-bridge modular multilevel converters (MMCs). An initial theoretical study concludes that dc circuit breakers (CB) energy dissipation will depend on inductance and ...
D. Jovcic   +3 more
semanticscholar   +1 more source

Improved Modulation Technique in Cascaded H‐Bridge Inverters for Fault‐Tolerant With Full Bridge Single Phase Rectifier Structure

open access: yesIET Power Electronics
This paper presents a novel fault‐tolerant approach for cascaded H‐bridge inverters with a full‐bridge single‐phase rectifier cell structure. Upon a fault, the faulty cell is disconnected from the circuit, and the inverter switches from normal operation (
Kasra Khalili, Jalal Nazarzadeh
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

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