Results 71 to 80 of about 274,854 (307)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Topology Selection of LLC Resonant Converter Applied in PETT
Kongzhi Yu Xinxi Jishu, 2017 LLC resonant converter is the key part of power electronic traction transformer (PETT), and the choice of its topology is critical. It analyzed the LLC resonant converter with symmetrical half bridge, asymmetrical half bridge and full bridge structure ...
CHEN Jiang, LIU Huadong, HUANG Zihao
doaj
Perancangan Dan Simulasi Full Bridge Inverter Lima Tingkat Dengan Dual Buck Converter Terhubung Jaringan Satu Fasa [PDF]
, 2014 Inverter merupakan perangkat elektronika daya yang berfungsi mengonversi sumber searah menjadi bolak-Balik. Full bridge inverter adalah satu jenisnya yang mampu menghasilkan tegangan tiga tingkat jika menggunakan teknik modulasi unipolar ...
Ashari, M. (Mochamad) +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A ripple reduction method for a two stages battery charger with multi-winding transformer using notch filter [PDF]
, 2017 This paper presents a two-stage battery charger consisting of a bridgeless Totem-pole power factor correction (TP-PFC) circuit and a full bridge converter with a multi-winding transformer.
Allanf, Peter +5 more
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Alone Self-Excited Induction Generators [PDF]
, 2016 In recent years, some converter structures and analyzing methods for the voltage regulation of stand-alone self-excited induction generators (SEIGs) have been introduced.
Doser, TL, Kesler, S
core +2 more sources
Circuit Structure and Control Method to Reduce Size and Harmonic Distortion of Interleaved Dual Buck Inverter [PDF]
, 2020 A new circuit structure and control method for a high power interleaved dual-buck inverter are proposed. The proposed inverter consists of six switches, four diodes and two inductors, uses a dual-buck structure to eliminate zero-cross distortion, and ...
Cho, Min-Gi +4 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source