Results 141 to 150 of about 2,281,021 (295)

Thermostable Bioluminescent Intercalating Dyes for Real‐Time, Integrated Nucleic Acid Amplification and Detection

open access: yesAngewandte Chemie, EarlyView.
We present a bioluminescent diagnostic platform that integrates DNA amplification and detection in a single step. The engineering of thermostable luciferase‐intercalating dye conjugates and controlled release of caged luciferin substrates enable real‐time, detection of attomolar concentrations of viral DNA within 30 min.
Yosta de Stigter   +8 more
wiley   +2 more sources

Widely-Linear Digital Self-Interference Cancellation in Full-Duplex USRP Transceiver. [PDF]

open access: yesSensors (Basel), 2022
Despina-Stoian C   +5 more
europepmc   +1 more source

Bidirectional Integrated Sensing and Communication: Full-Duplex or Half-Duplex?

open access: yes
A bidirectional integrated sensing and communication (ISAC) system is proposed, in which a pair of transceivers carry out two-way communication and mutual sensing.
Liu, Yuanwei, Wang, Zhaolin, Mu, Xidong
core   +1 more source

Half-duplex or full-duplex relaying: a capacity analysis under self-interference

open access: yes, 2013
In this paper multi-antenna half-duplex and full-duplex relaying are compared from the perspective of achievable rates. Full-duplexing operation requires additional resources at the relay such as antennas and RF chains for self-interference cancellation.
Elza Erkip   +5 more
core   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim   +12 more
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

Assembly of Protein‐DNA Framework Nanostructures: Structurally Defining Protein‐DNA Interfaces With Aptamer

open access: yesAngewandte Chemie, EarlyView.
Rationally designed DNA multivalent aptamers direct specific protein binding to drive self‐assembly into protein‐DNA frameworks (PDFs). Structurally defined protein‐aptamer interfaces organize proteins into triangles, linear and ladderlike chains, and periodic two‐dimensional arrays, enabling precise control over orientation, connectivity, and overall ...
Zhe Zhang   +11 more
wiley   +2 more sources

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

open access: yesAdvanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham   +8 more
wiley   +1 more source

Three-Mode Opportunistic Full-Duplex Switching

open access: yesIEEE Access
This paper proposes a novel opportunistic full-duplex (FD) scheme switching among three duplex modes (DMs) of half duplex (HD), three node FD (TNFD) and bidirectional FD (BiFD) for the cellular systems.
Hyungseop Son, Kwonhue Choi
doaj   +1 more source

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