Results 91 to 100 of about 26,933,679 (277)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Full Reference Image Quality Assessment using Siamese Neural Network [PDF]

open access: yes, 2023
This study aims to explore the application of Siamese Neural Networks (SNN) in Full-Reference Image Quality Assessment (FR-IQA). The goal is to develop an efficient and accurate model to predict perceived image quality and correlate it with human scores.
Islam, Akib Jayed
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Perceptual Error Logarithm: An Efficient and Effective Analytical Method for Full-Reference Image Quality Assessment

open access: yesIEEE Access
In this paper, we propose a new perceptual analytical method for full-reference image assessment. Techniques used in multimedia applications often introduce distortions, which can significantly degrade image and video quality.
Sergio A. C. Bezerra   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A Novel Full-Reference Color Image Quality Assessment Based on Energy Computation in the Wavelet Domain

open access: yesJournal of Intelligent Systems, 2013
This article presents a novel full-reference (FR) image quality assessment (QA) algorithm by depicting the sub-band characteristics in the wavelet domain.
Hanumantharaju M.C.   +3 more
doaj   +1 more source

Adaptation of Full-Reference Image Quality Assessment Methods for Automatic Visual Evaluation of the Surface Quality of 3D Prints

open access: yesElektronika ir Elektrotechnika, 2019
Automatic visual quality assessment of the 3D printed surfaces is currently one of the most demanding challenges in additive manufacturing. Regardless of the applications of the computer vision for the 3D printing process monitoring purposes, a reliable ...
Krzysztof Okarma, Jaroslaw Fastowicz
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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